Alaeddin Hakam

790 total citations
26 papers, 646 citations indexed

About

Alaeddin Hakam is a scholar working on Molecular Biology, Oncology and Infectious Diseases. According to data from OpenAlex, Alaeddin Hakam has authored 26 papers receiving a total of 646 indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 16 papers in Oncology and 3 papers in Infectious Diseases. Recurrent topics in Alaeddin Hakam's work include PARP inhibition in cancer therapy (15 papers), DNA Repair Mechanisms (7 papers) and DNA and Nucleic Acid Chemistry (6 papers). Alaeddin Hakam is often cited by papers focused on PARP inhibition in cancer therapy (15 papers), DNA Repair Mechanisms (7 papers) and DNA and Nucleic Acid Chemistry (6 papers). Alaeddin Hakam collaborates with scholars based in United States, Hungary and Germany. Alaeddin Hakam's co-authors include Kálman G. Büki, Ernest Kun, Pál I. Bauer, E. Kirsten, Jerome Mendeleyev, É. Kun, Paul Bauer, Ercole L. Cavalieri, Eleanor G. Rogan and Jerome McLick and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Alaeddin Hakam

26 papers receiving 621 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alaeddin Hakam United States	13	409	386	108	59	57	26	646
David P. Ringer United States	20	264 0.6×	803 2.1×	51 0.5×	38 0.6×	23 0.4×	58	1.1k
Masaichi Warizaya Japan	13	198 0.5×	339 0.9×	63 0.6×	55 0.9×	76 1.3×	22	592
Zigao Yuan China	17	208 0.5×	497 1.3×	48 0.4×	10 0.2×	46 0.8×	36	697
Ashok J. Chavan United States	12	140 0.3×	463 1.2×	236 2.2×	49 0.8×	7 0.1×	20	755
Paul Tunnah France	4	323 0.8×	626 1.6×	58 0.5×	13 0.2×	5 0.1×	5	1.1k
Shanthi R. Paranawithana United States	13	141 0.3×	583 1.5×	35 0.3×	6 0.1×	17 0.3×	15	735
Jane Kepros United States	5	281 0.7×	251 0.7×	23 0.2×	6 0.1×	16 0.3×	7	660
Shuqiang Chen China	17	56 0.1×	418 1.1×	137 1.3×	14 0.2×	39 0.7×	77	1.0k
Swati Prasad United States	13	74 0.2×	558 1.4×	28 0.3×	8 0.1×	14 0.2×	16	833
Jason Labutti United States	10	92 0.2×	358 0.9×	73 0.7×	7 0.1×	14 0.2×	10	460

Countries citing papers authored by Alaeddin Hakam

Since Specialization

Citations

This map shows the geographic impact of Alaeddin Hakam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alaeddin Hakam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alaeddin Hakam more than expected).

Fields of papers citing papers by Alaeddin Hakam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alaeddin Hakam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alaeddin Hakam. The network helps show where Alaeddin Hakam may publish in the future.

Co-authorship network of co-authors of Alaeddin Hakam

This figure shows the co-authorship network connecting the top 25 collaborators of Alaeddin Hakam. A scholar is included among the top collaborators of Alaeddin Hakam based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alaeddin Hakam. Alaeddin Hakam is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kun, Ernest, E. Kirsten, Alaeddin Hakam, Pál I. Bauer, & Jerome Mendeleyev. (2008). Dependence of trans‐ADP‐ribosylation and nuclear glycolysis on the Arg 34–ATP complex of Zn²⁺ finger I of poly‐ADP‐ribose polymerase‐1. FEBS Letters. 582(18). 2709–2713. 1 indexed citations

Kun, Ernest, E. Kirsten, Alaeddin Hakam, Pál I. Bauer, & Jerome Mendeleyev. (2007). Identification of poly(ADP-ribose) polymerase-1 as the OXPHOS-generated ATP sensor of nuclei of animal cells. Biochemical and Biophysical Research Communications. 366(2). 568–573. 8 indexed citations

Bauer, Pál I., et al.. (2002). Anti-cancer action of 4-iodo-3-nitrobenzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose) polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose) polymerase protease. Biochemical Pharmacology. 63(3). 455–462. 15 indexed citations

Bauer, Pál I., István Kenessey, Kálman G. Büki, et al.. (2001). Molecular interactions between poly(ADP‐ribose) polymerase (PARP I) and topoisomerase I (Topo I): identification of topology of binding. FEBS Letters. 506(3). 239–242. 39 indexed citations

Mendeleyev, Jerome, E. Kirsten, Alaeddin Hakam, Kálman G. Büki, & Ernest Kun. (1995). Potential chemotherapeutic activity of 4-iodo-3-nitrobenzamide. Biochemical Pharmacology. 50(5). 705–714. 57 indexed citations

Büki, Kálman G., Pál I. Bauer, Alaeddin Hakam, & Ernest Kun. (1995). Identification of Domains of Poly(ADP-ribose) Polymerase for Protein Binding and Self-association. Journal of Biological Chemistry. 270(7). 3370–3377. 58 indexed citations

Cole, Gerald A., Gerhard Bauer, E. Kirsten, et al.. (1991). Inhibition of HIV-1 IIIb replication in AA-2 and NT-2 cells in culture by two ligands of poly (ADP-ribose) polymerase: 6-amino-1,2-benzopyrone and 5-iodo-6-amino-1,2-benzopyrone. Biochemical and Biophysical Research Communications. 180(2). 504–514. 22 indexed citations

Büki, Kálman G., Pál I. Bauer, Jerome Mendeleyev, Alaeddin Hakam, & Ernest Kun. (1991). Destabilization of Zn²⁺ coordination in ADP‐ribose transferase (polymerizing) by 6‐nitroso‐1,2‐benzopyrone coincidental with inactivation of the polymerase but not the DNA binding function. FEBS Letters. 290(1-2). 181–185. 21 indexed citations

Bauer, Paul, Kálman G. Büki, Alaeddin Hakam, & É. Kun. (1990). Macromolecular association of ADP-ribosyltransferase and its correlation with enzymic activity. Biochemical Journal. 270(1). 17–26. 72 indexed citations

10.

Hakam, Alaeddin, Jerome McLick, Kálman G. Büki, & Ernest Kun. (1987). Catalytic activities of synthetic octadeoxyribonucleotides as coenzymes of poly(ADP‐ribose) polymerase and the identification of a new enzyme inhibitory site. FEBS Letters. 212(1). 73–78. 16 indexed citations

11.

Tseng, Alexander M., Edward B. Jakobovits, E. Kirsten, et al.. (1987). Prevention of tumorigenesis of oncogene-transformed rat fibroblasts with DNA site inhibitors of poly(ADP ribose) polymerase.. Proceedings of the National Academy of Sciences. 84(4). 1107–1111. 47 indexed citations

12.

McLick, Jerome, Alaeddin Hakam, Pál I. Bauer, et al.. (1987). Benzamide-DNA interactions: Deductions from binding, enzyme kinetics and from X-ray structural analysis of a 9-ethyladenine-benzamide adduct. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 909(1). 71–83. 9 indexed citations

13.

McLick, Jerome, Pál I. Bauer, Alaeddin Hakam, & Ernest Kun. (1987). Covalent binding of 4-carbamoylbenzenediazonium chloride to deoxyguanine bases of DNA resulting in apparent irreversible inhibition of poly(adenosine diphosphoribose) polymerase at the nicotinamide binding site. Biochemistry. 26(8). 2226–2231. 4 indexed citations

14.

Bauer, Pál I., Alaeddin Hakam, & Ernest Kun. (1986). Mechanisms of poly(ADP‐ribose) polymerase catalysis; mono‐ADP‐ribosylation of poly(ADP‐ribose) polymerase at nanomolar concentrations of NAD. FEBS Letters. 195(1-2). 331–338. 33 indexed citations

15.

Hakam, Alaeddin, Jerome McLick, & Ernest Kun. (1986). Simultaneous determination of mono- and poly(ADP-ribose) in vivo by tritium labelling and direct high-performance liquid chromatographic separation. Journal of Chromatography A. 359. 275–284. 5 indexed citations

16.

Kirsten, E., George Jackowski, Jerome McLick, et al.. (1985). Cellular regulation of poly(ADP) ribosylation of proteins. Experimental Cell Research. 161(1). 41–52. 12 indexed citations

17.

Hakam, Alaeddin & Ernest Kun. (1985). High-performance liquid chromatography of in vitro synthesized poly(adp-ribose) on ion-exchange columns, separation of oligomers of varying chain length and estimation of apparent branching. Journal of Chromatography A. 330(2). 287–298. 7 indexed citations

18.

Rogan, Eleanor G., Alaeddin Hakam, & Ercole L. Cavalieri. (1983). Structure elucidation of a 6-methylbenzo[a]pyrene-DNA adduct formed by horseradish peroxidase in vitro and mouse skin in vivo. Chemico-Biological Interactions. 47(1). 111–122. 12 indexed citations

19.

Hakam, Alaeddin, et al.. (1980). Enzymatic copolymerization of nitroxide labelled uridine derivatives with nucleoside diphosphates. International Journal of Biological Macromolecules. 2(1). 49–51. 11 indexed citations

20.

Bobst, Albert M., et al.. (1979). Electron spin resonance melting of chemically spin-labeled nucleic acids. Archives of Biochemistry and Biophysics. 194(1). 171–178. 6 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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