Aaron Schain

2.6k total citations · 1 hit paper
22 papers, 1.9k citations indexed

About

Aaron Schain is a scholar working on Psychiatry and Mental health, Pathology and Forensic Medicine and Neurology. According to data from OpenAlex, Aaron Schain has authored 22 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Psychiatry and Mental health, 10 papers in Pathology and Forensic Medicine and 8 papers in Neurology. Recurrent topics in Aaron Schain's work include Migraine and Headache Studies (14 papers), Trigeminal Neuralgia and Treatments (9 papers) and Neuroscience of respiration and sleep (4 papers). Aaron Schain is often cited by papers focused on Migraine and Headache Studies (14 papers), Trigeminal Neuralgia and Treatments (9 papers) and Neuroscience of respiration and sleep (4 papers). Aaron Schain collaborates with scholars based in United States, Israel and Ireland. Aaron Schain's co-authors include Jaime Grutzendler, Carlo Condello, Rami Burstein, Agustin Melo‐Carrillo, Andrew M. Strassman, Peng Yuan, Jennifer Stratton, Rodrigo Noseda, Rony‐Reuven Nir and Roa Harb and has published in prestigious journals such as Nature Medicine, Nature Communications and Journal of Neuroscience.

In The Last Decade

Aaron Schain

20 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

2015 468 citations Carlo Condello, Peng Yuan et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Aaron Schain United States	16	767	762	736	450	336	22	1.9k
Vanessa Kainz United States	17	1.9k 2.5×	424 0.6×	741 1.0×	896 2.0×	271 0.8×	20	2.5k
Martina Vendrame United States	24	751 1.0×	724 1.0×	418 0.6×	70 0.2×	510 1.5×	54	2.6k
Marcela Romero‐Reyes United States	21	614 0.8×	154 0.2×	510 0.7×	366 0.8×	213 0.6×	39	1.3k
Jiyun Peng China	13	181 0.2×	685 0.9×	709 1.0×	68 0.2×	661 2.0×	18	1.6k
Melissa Manis United States	12	123 0.2×	1.1k 1.5×	945 1.3×	64 0.1×	401 1.2×	16	2.1k
Ukpong B. Eyo United States	25	182 0.2×	1.9k 2.5×	563 0.8×	83 0.2×	826 2.5×	44	2.8k
Mario Stampanoni Bassi Italy	25	97 0.1×	626 0.8×	213 0.3×	507 1.1×	338 1.0×	71	1.9k
Ditte Lovatt United States	12	244 0.3×	718 0.9×	392 0.5×	85 0.2×	1.2k 3.6×	13	2.6k
Valeria Studer Italy	24	119 0.2×	667 0.9×	165 0.2×	827 1.8×	390 1.2×	40	1.9k
Eugene V. Golanov United States	28	173 0.2×	500 0.7×	403 0.5×	295 0.7×	774 2.3×	77	2.5k

Countries citing papers authored by Aaron Schain

Since Specialization

Citations

This map shows the geographic impact of Aaron Schain's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Aaron Schain with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Aaron Schain more than expected).

Fields of papers citing papers by Aaron Schain

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Aaron Schain. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Aaron Schain. The network helps show where Aaron Schain may publish in the future.

Co-authorship network of co-authors of Aaron Schain

This figure shows the co-authorship network connecting the top 25 collaborators of Aaron Schain. A scholar is included among the top collaborators of Aaron Schain based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Aaron Schain. Aaron Schain is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kamen, Yasmine, et al.. (2025). Label-free and fluorescence imaging of oligodendrocytes and myelin. PubMed. 3(1). 33–33.

Schain, Aaron, Diego Fajardo, Andrew M. Strassman, et al.. (2025). OnabotulinumtoxinA alters pro- and anti-inflammatory dural macrophage response to CSD in female mice. Cephalalgia. 45(9). 2235423786–2235423786.

Melo‐Carrillo, Agustin, Aaron Schain, Andrew M. Strassman, & Rami Burstein. (2020). Activation of Peripheral and Central Trigeminovascular Neurons by Seizure: Implications for Ictal and Postictal Headache. Journal of Neuroscience. 40(27). 5314–5326. 8 indexed citations

Melo‐Carrillo, Agustin, Andrew M. Strassman, Aaron Schain, et al.. (2020). Combined onabotulinumtoxinA/atogepant treatment blocks activation/sensitization of high-threshold and wide-dynamic range neurons. Cephalalgia. 41(1). 17–32. 28 indexed citations

Melo‐Carrillo, Agustin, Andrew M. Strassman, Aaron Schain, et al.. (2020). Extracranial Injections of OnabotulinumtoxinA in Combination with Intravenous Injection of Atogepant Attenuates Activation and Sensitization of HT and WDR Neurons by CSD (4287). Neurology. 94(15_supplement). 1 indexed citations

Schain, Aaron, Agustin Melo‐Carrillo, Jennifer Stratton, Andrew M. Strassman, & Rami Burstein. (2019). CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura. Journal of Neuroscience. 39(30). 6001–6011. 54 indexed citations

Noseda, Rodrigo, Aaron Schain, Agustin Melo‐Carrillo, et al.. (2019). Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier. Cephalalgia. 40(3). 229–240. 71 indexed citations

Melo‐Carrillo, Agustin, Aaron Schain, Jennifer Stratton, Andrew M. Strassman, & Rami Burstein. (2019). Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood–brain barrier. Pain. 161(5). 1037–1043. 29 indexed citations

Schain, Aaron, Agustin Melo‐Carrillo, Sait Ashina, Andrew M. Strassman, & Rami Burstein. (2019). Celecoxib reduces cortical spreading depression–induced macrophage activation and dilatation of dural but not pial arteries in rodents: implications for mechanism of action in terminating migraine attacks. Pain. 161(5). 1019–1026. 12 indexed citations

10.

Schain, Aaron, Agustin Melo‐Carrillo, David Borsook, et al.. (2018). Activation of pial and dural macrophages and dendritic cells by cortical spreading depression. Annals of Neurology. 83(3). 508–521. 74 indexed citations

11.

Schain, Aaron, Agustin Melo‐Carrillo, Andrew M. Strassman, & Rami Burstein. (2017). Cortical Spreading Depression Closes Paravascular Space and Impairs Glymphatic Flow: Implications for Migraine Headache. Journal of Neuroscience. 37(11). 2904–2915. 177 indexed citations

12.

Melo‐Carrillo, Agustin, Andrew M. Strassman, Rony‐Reuven Nir, et al.. (2017). Fremanezumab—A Humanized Monoclonal Anti-CGRP Antibody—Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors. Journal of Neuroscience. 37(44). 10587–10596. 151 indexed citations

13.

Melo‐Carrillo, Agustin, Rodrigo Noseda, Rony‐Reuven Nir, et al.. (2017). Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody. Journal of Neuroscience. 37(30). 7149–7163. 125 indexed citations

14.

Burstein, Rami, et al.. (2017). Extracranial origin of headache. Current Opinion in Neurology. 30(3). 263–271. 40 indexed citations

15.

Blake, Pamela G., Catherine Buettner, Efstathios Papavassiliou, et al.. (2016). Upregulation of inflammatory gene transcripts in periosteum of chronic migraineurs: Implications for extracranial origin of headache. Annals of Neurology. 79(6). 1000–1013. 68 indexed citations

16.

Condello, Carlo, Peng Yuan, Aaron Schain, & Jaime Grutzendler. (2015). Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Nature Communications. 6(1). 6176–6176. 468 indexed citations breakdown →

17.

Buettner, Catherine, Rony‐Reuven Nir, Suzanne M. Bertisch, et al.. (2015). Simvastatin and vitamin D for migraine prevention: A randomized, controlled trial. Annals of Neurology. 78(6). 970–981. 81 indexed citations

18.

Schain, Aaron, Robert Hill, & Jaime Grutzendler. (2014). Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy. Nature Medicine. 20(4). 443–449. 129 indexed citations

19.

Condello, Carlo, Aaron Schain, & Jaime Grutzendler. (2011). Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition. Scientific Reports. 1(1). 19–19. 81 indexed citations

20.

Liu, Zhiqiang, Carlo Condello, Aaron Schain, Roa Harb, & Jaime Grutzendler. (2010). CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-β Phagocytosis. Journal of Neuroscience. 30(50). 17091–17101. 227 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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