A. Paul Krapcho

3.8k total citations · 1 hit paper
132 papers, 3.1k citations indexed

About

A. Paul Krapcho is a scholar working on Organic Chemistry, Molecular Biology and Toxicology. According to data from OpenAlex, A. Paul Krapcho has authored 132 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 101 papers in Organic Chemistry, 47 papers in Molecular Biology and 20 papers in Toxicology. Recurrent topics in A. Paul Krapcho's work include Cancer therapeutics and mechanisms (23 papers), Bioactive Compounds and Antitumor Agents (20 papers) and Synthesis and Biological Evaluation (18 papers). A. Paul Krapcho is often cited by papers focused on Cancer therapeutics and mechanisms (23 papers), Bioactive Compounds and Antitumor Agents (20 papers) and Synthesis and Biological Evaluation (18 papers). A. Paul Krapcho collaborates with scholars based in United States, Italy and France. A. Paul Krapcho's co-authors include Allen Lovey, Edwin G. E. Jahngen, Miles P. Hacker, Claudia Sissi, Manlio Palumbo, Zelleka Getahun, Ernesto Menta, Silvano Spinelli, Ambrogio Oliva and Lori Hazlehurst and has published in prestigious journals such as Journal of the American Chemical Society, PLoS ONE and Chemical Communications.

In The Last Decade

A. Paul Krapcho

125 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Synthetic Applications of Dealkoxycarbonylations of Malonate Esters, β-Keto Esters, α-Cyano Esters and Related Compounds in Dipolar Aprotic Media - Part I

1982 346 citations A. Paul Krapcho profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
A. Paul Krapcho United States	29	2.1k	1.1k	296	264	231	132	3.1k
Bala Krishnan United States	24	2.3k 1.1×	1.2k 1.1×	144 0.5×	270 1.0×	462 2.0×	39	3.4k
J. A. Joule United Kingdom	26	2.0k 0.9×	552 0.5×	159 0.5×	179 0.7×	216 0.9×	246	2.9k
Pàl Sohár Hungary	26	2.8k 1.3×	1.1k 1.1×	86 0.3×	317 1.2×	160 0.7×	334	3.3k
Robert K. Boeckman United States	36	2.6k 1.3×	786 0.7×	82 0.3×	243 0.9×	392 1.7×	114	3.3k
P. L. Fuchs United States	40	4.7k 2.2×	1.7k 1.6×	138 0.5×	185 0.7×	366 1.6×	234	6.1k
M. S. MANHAS United States	33	3.3k 1.6×	876 0.8×	56 0.2×	208 0.8×	240 1.0×	175	3.8k
Joëlle Dubois France	31	2.3k 1.1×	1.2k 1.1×	145 0.5×	651 2.5×	360 1.6×	132	3.3k
G. QUEGUINER France	39	5.1k 2.4×	1.4k 1.3×	141 0.5×	107 0.4×	266 1.2×	276	5.7k
Anthony J. Mancuso United States	4	2.2k 1.0×	822 0.8×	55 0.2×	125 0.5×	325 1.4×	4	2.8k
Charles M. Marson United Kingdom	24	1.9k 0.9×	928 0.9×	54 0.2×	186 0.7×	198 0.9×	117	2.7k

Countries citing papers authored by A. Paul Krapcho

Since Specialization

Citations

This map shows the geographic impact of A. Paul Krapcho's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Paul Krapcho with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Paul Krapcho more than expected).

Fields of papers citing papers by A. Paul Krapcho

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Paul Krapcho. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Paul Krapcho. The network helps show where A. Paul Krapcho may publish in the future.

Co-authorship network of co-authors of A. Paul Krapcho

This figure shows the co-authorship network connecting the top 25 collaborators of A. Paul Krapcho. A scholar is included among the top collaborators of A. Paul Krapcho based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. Paul Krapcho. A. Paul Krapcho is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bianco, Sara, Caterina Musetti, A. Paul Krapcho, Manlio Palumbo, & Claudia Sissi. (2013). Ni2+ and Cu2+ complexes of a phenanthroline-based ligand bind to G-quadruplexes at non-overlapping sites. Chemical Communications. 49(73). 8057–8057. 14 indexed citations

Bianco, Sara, Caterina Musetti, Silvia Sparapani, et al.. (2010). Bis-phenanthroline derivatives as suitable scaffolds for effective G-quadruplex recognition. Dalton Transactions. 39(25). 5833–5833. 35 indexed citations

Lucatello, Lorena, et al.. (2008). Perylene side chains modulate G-quadruplex conformation in biologically relevant DNA sequences. Bioorganic & Medicinal Chemistry. 16(20). 9331–9339. 22 indexed citations

Krapcho, A. Paul. (2007). Recent synthetic applications of the dealkoxycarbonylation reaction. Part 2. Dealkoxycarbonylations of β-keto esters, α-cyanoesters and related analogues. ARKIVOC. 2007(2). 54–120. 20 indexed citations

Sissi, Claudia, Lorena Lucatello, A. Paul Krapcho, et al.. (2006). Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition. Bioorganic & Medicinal Chemistry. 15(1). 555–562. 66 indexed citations

Sissi, Claudia, Elisabetta Leo, Stefano Moro, et al.. (2003). Antitumor AZA-anthrapyrazoles: biophysical and biochemical studies on 8- and 9-aza regioisomers. Biochemical Pharmacology. 67(4). 631–642. 16 indexed citations

Chou, Kai-Ming, A. Paul Krapcho, David Horn, & Miles P. Hacker. (2002). Characterization of anthracenediones and their photoaffinity analogs. Biochemical Pharmacology. 63(6). 1143–1147. 9 indexed citations

Sissi, Claudia, Stefano Moro, Sara N. Richter, et al.. (2001). DNA-Interactive Anticancer Aza-Anthrapyrazoles: Biophysical and Biochemical Studies Relevant to the Mechanism of Action. Molecular Pharmacology. 59(1). 96–103. 15 indexed citations

Krapcho, A. Paul, et al.. (2000). Synthesis and antitumor activities of 5-methyl-1- and 2-[[2-dimethylaminoethyl]amino]-aza-thiopyranoindazoles. Bioorganic & Medicinal Chemistry Letters. 10(3). 305–308. 9 indexed citations

10.

Krapcho, A. Paul, et al.. (1998). General synthetic route to benz[g]isoquinolines (2‐azaanthracenes). Journal of Heterocyclic Chemistry. 35(3). 669–674. 10 indexed citations

11.

Hazlehurst, Lori, A. Paul Krapcho, & Miles P. Hacker. (1995). Comparison of AZA-anthracenedione-induced DNA damage and cytotoxicity in experimental tumor cells. Biochemical Pharmacology. 50(7). 1087–1094. 41 indexed citations

12.

Hazlehurst, Lori, A. Paul Krapcho, & Miles P. Hacker. (1995). Correlation of DNA reactivity and cytotoxicity of a new class of anticancer agents: Aza-anthracenediones. Cancer Letters. 91(1). 115–124. 34 indexed citations

13.

Palumbo, Manlio, Claudia Sissi, Giovanni Capranico, et al.. (1995). Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives.. Molecular Pharmacology. 48(1). 30–38. 53 indexed citations

14.

Krapcho, A. Paul, et al.. (1994). 6,9-Bis[(aminoalkyl)amino]benzo[g]isoquinoline-5,10-diones. A Novel Class of Chromophore-Modified Antitumor Anthracene-9,10-diones: Synthesis and Antitumor Evaluations. Journal of Medicinal Chemistry. 37(6). 828–837. 92 indexed citations

15.

Krapcho, A. Paul, et al.. (1990). Heterosubstituted anthracene-9,10-dione analogs. The synthesis and antitumor evaluation of 5,8-bis[(aminoalkyl)amino]naphtho[2,3-b]thiophene-4,9-diones. Journal of Medicinal Chemistry. 33(9). 2651–2655. 40 indexed citations

16.

Krapcho, A. Paul, et al.. (1977). Potassium permanganate oxidations of terminal olefins and acetylenes to carboxylic acids of one less carbon. The Journal of Organic Chemistry. 42(23). 3749–3753. 50 indexed citations

17.

Krapcho, A. Paul & Edwin G. E. Jahngen. (1974). General synthetic route to cycloalkylidenecycloalkanes. Reactions of .alpha.-anions of cycloalkanecarboxylic acid salts with cycloalkanones. The Journal of Organic Chemistry. 39(12). 1650–1653. 37 indexed citations

18.

Krapcho, A. Paul. (1973). Decarboxylations geminal diesters, β-keto esters and α-cyanoesters effected by sodium chloride in dimethyl sulfoxide. Tetrahedron Letters. 957–960. 1 indexed citations

19.

Krapcho, A. Paul & Allen Lovey. (1973). Decarbalkoxylations of geminal diesters, β-keto esters and α-cyano esters effected by sodium chloride in dimethyl sulpoxide. Tetrahedron Letters. 14(12). 957–960. 160 indexed citations

20.

Krapcho, A. Paul, et al.. (1969). Acetolyse de tosylates spiranniques de conformation figee par un groupe tertio-butyle. Tetrahedron Letters. 10(33). 2799–2802.

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