Citation Impact
Citing Papers
ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
2008 Standout
ROS stress in cancer cells and therapeutic implications
2004 Standout
Use of arsenic trioxide (As2O3) in the treatment of patients with acute promyelocytic leukemia
2003 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
1998
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
2008
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
Modulation of p53, c-fos, RARE, cyclin A, and cyclin D1 expression in human leukemia (HL-60) cells exposed to arsenic trioxide
2009
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
2012 Standout
Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide
1998
The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine
2011 Standout
Signal transduction pathways and transcription factors triggered by arsenic trioxide in leukemia cells
2010
Chronic inflammation and oxidative stress in human carcinogenesis
2007
Arsenite Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore
1999
A New Protein Conjugation System in Human
1998 StandoutNobel
Promoting apoptosis as a strategy for cancer drug discovery
2005
Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes
2005 Standout
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
1998 Standout
Pharmacokinetics, Metabolism, and Carcinogenicity of Arsenic
2001
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)
1999
Genetic toxicology of a paradoxical human carcinogen, arsenic: a review
2001
Regulation of the G2/M transition by p53
2001 Standout
Effect of arsenic trioxide on viability, proliferation, and apoptosis in human megakaryocytic leukemia cell lines
1999
Role of autophagy in cancer
2007 Standout
Topoisomerase I-DNA Complexes Contribute to Arsenic Trioxide-induced Apoptosis
2004
Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3
2004
The Bcl2 family: regulators of the cellular life-or-death switch
2002 Standout
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia
2000
SUMO
2005 Standout
Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines
2003
p53 inhibits entry into mitosis when DNA synthesis is blocked
1999
Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer
2002 Standout
Characterization of molecular events in a series of bladder urothelial carcinoma cell lines with progressive resistance to arsenic trioxide
2004
Molecular genetics of acute promyelocytic leukemia
1999
Pathways of retinoic acid- or arsenic trioxide-induced PML/RARα catabolism, role of oncogene degradation in disease remission
2001
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro
1999
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Death and anti-death: tumour resistance to apoptosis
2002 Standout
Oxidative Stress in Cancer
2020 Standout
The thioredoxin antioxidant system
2013 Standout
Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all‐trans retinoic acid
2000
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2003 Standout
Heavy Metal Toxicity and the Environment
2012 Standout
Effect of Arsenic Trioxide on Cell Cycle Arrest in Head and Neck Cancer Cell Line PCI-1
1999
Autophagy in cell death: an innocent convict?
2005 Standout
Acute promyelocytic leukaemia: novel insights into the mechanisms of cure
2010
The Bcl-2 apoptotic switch in cancer development and therapy
2007 Standout
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
The Nuclear Dot Protein Sp100, Characterization of Domains Necessary for Dimerization, Subcellular Localization, and Modification by Small Ubiquitin-like Modifiers
1999
The BCL-2 protein family: opposing activities that mediate cell death
2007 Standout
Dietary phytosterols: A review of metabolism, benefits and side effects
1995
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
In-vitro cytotoxic and genotoxic effects of arsenic trioxide on human leukemia (HL-60) cells using the MTT and alkaline single cell gel electrophoresis (Comet) assays
2007
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
Arsenic Trioxide: Acute Promyelocytic Leukemia and Beyond
2002
Inhibition of Mitochondrial Respiration
2003
Evidence of an immunologic mechanism behind the therapeutical effects of arsenic trioxide (As2O3) on myeloma cells
2001
The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects
2002
Oxidative stress and apoptosis: a new treatment paradigm in cancer
2006
The Effects of Arsenic Trioxide on DNA Synthesis and Genotoxicity in Human Colon Cancer Cells
2010
BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity.
2000
Molecular Targets of Arsenic Trioxide in Malignant Cells
2002
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2012 Standout
United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia
2001 Standout
Combined Arsenic and Retinoic Acid Treatment Enhances Differentiation and Apoptosis in Arsenic-Resistant NB4 Cells
1998
GENOTOXIC MECHANISMS OF ARSENIC TRIOXIDE IN HUMAN JURKAT T-LYMPHOMA CELLS.
2008
Arsenic Trioxide and Melarsoprol Induce Programmed Cell Death in Myeloid Leukemia Cell Lines and Function in a PML and PML-RAR Independent Manner
1998
Histone deacetylases (HDACs): characterization of the classical HDAC family
2003 Standout
Trivalent Antimonials Induce Degradation of the PML-RAR Oncoprotein and Reorganization of the Promyelocytic Leukemia Nuclear Bodies in Acute Promyelocytic Leukemia NB4 Cells
1998
Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway.
1999
The Effects Of Arsenic Trioxide (As2O3) On Human Megakaryocytic Leukemia Cell Lines With a Comparison of its Effects on Other Cell Lineages
2000
Cell Apoptosis Induced by Carcinogenic Metals
2001
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Three-dimensional organization of promyelocytic leukemia nuclear bodies
2010 StandoutNobel
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis
2001
Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients.
1999
Ascorbic acid enhances arsenic trioxide–induced cytotoxicity in multiple myeloma cells
2001
Malignant Cells Can Be Sensitized to Undergo Growth Inhibition and Apoptosis by Arsenic Trioxide Through Modulation of the Glutathione Redox System
1999
Common Properties of Nuclear Body Protein SP100 and TIF1α Chromatin Factor: Role of SUMO Modification
2001
Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.
2003
Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents
2003
Arsenic Trioxide Selectively Induces Acute Promyelocytic Leukemia Cell Apoptosis Via a Hydrogen Peroxide-Dependent Pathway
1999
Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins
1999 StandoutNobel
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
2007
Arsenic-Induced Genotoxic and Cytotoxic Effects in Human Keratinocytes, Melanocytes and Dendritic Cells
2004
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
The Ecology of Arsenic
2003 StandoutScience
Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia
2001 Nobel
Leukocytosis and the Retinoic Acid Syndrome in Patients With Acute Promyelocytic Leukemia Treated With Arsenic Trioxide
2000
Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
2001
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells.
2003
Inhibition of Macroautophagy Triggers Apoptosis
2005 Standout
Acute promyelocytic leukemia: from highly fatal to highly curable
2008
Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines.
2000
Protein Modification by SUMO
2004 Standout
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy
1999 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Cell apoptosis induced by carcinogenic metals
2001
Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia
1999
Mechanisms of action of arsenic trioxide.
2002
Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients
1997 Standout
Works of ZY Wang being referenced
The antiatherogenic effects of components isolated from pollen Typhae
1990
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
1996
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
1996