Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
RIP140-Targeted Repression of Gene Expression in Adipocytes
2005
Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes
2007
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
The regulation of cellular metabolism by tumor suppressor p53
2013
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Fatty liver in familial hypobetalipoproteinemia
2004
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Genetic determinants of hepatic steatosis in man
2011
Intramolecular Control of Protein Stability, Subnuclear Compartmentalization, and Coactivator Function of Peroxisome Proliferator-activated Receptor γ Coactivator 1α
2007
Metabolism and cancer: the circadian clock connection
2009
mTOR Signaling in Growth Control and Disease
2012 Standout
Inflammation and metabolic disorders
2006 StandoutNature
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
2011
MYC on the Path to Cancer
2012 Standout
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
2005 Nature
Brown and beige fat: development, function and therapeutic potential
2013 Standout
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
AKT/PKB Signaling: Navigating Downstream
2007 Standout
The Meter of Metabolism
2008
Autophagy regulates lipid metabolism
2009 StandoutNature
Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice
2008
Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
2012
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Insights into obesity and diabetes at the intersection of mouse and human genetics
2014
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Metformin increases the PGC-1α protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo
2006
Dissociating fatty liver and diabetes
2012
The multifaceted roles of fatty acid synthesis in cancer
2016
Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity
2016
Transcriptional coactivators PGC-1α and PGC-lβ control overlapping programs required for perinatal maturation of the heart
2008
Hormonal Regulation of Hepatic Glucose Production in Health and Disease
2011
PGC-1α is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle
2007
Nature and cause of mitochondrial dysfunction in Huntington’s disease: focusing on huntingtin and the striatum
2010
Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses
2020
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1α transcription coactivator
2007 Nature
Functional Brown Adipose Tissue in Healthy Adults
2009 Standout
Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy
2008
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Mitochondrial dysfunction in human pathologies
2006
Skeletal Muscle Fiber-type Switching, Exercise Intolerance, and Myopathy in PGC-1α Muscle-specific Knock-out Animals
2007
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
2013
Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance
2017
The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis
2016
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Autophagy in Human Health and Disease
2013 Standout
Cytosolic Phosphoenolpyruvate Carboxykinase Does Not Solely Control the Rate of Hepatic Gluconeogenesis in the Intact Mouse Liver
2007
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
2010
Metabolic Reprogramming in Dietary Restriction
2006
An Integrated View of Immunometabolism
2018
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Metabolic control through the PGC-1 family of transcription coactivators
2005 Standout
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
2012
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
2010
The PGC-1 cascade as a therapeutic target for heart failure
2010
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
2006
Targeting autophagy in cancer
2017 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes
2006
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339
2005
The Hallmarks of Aging
2013 Standout
Energy Metabolism in the Liver
2014 Standout
Transcriptional control of mitochondrial biogenesis: the central role of PGC-1
2008
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function
2008
Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly
2010
mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
2007 Nature
Insulin signaling to hepatic lipid metabolism in health and disease
2011
TORC2 Regulates Hepatic Insulin Signaling via a Mammalian Phosphatidic Acid Phosphatase, LIPIN1
2009
Calcineurin Regulates Skeletal Muscle Metabolism via Coordinated Changes in Gene Expression
2006
Thyroid Hormone and Adipocyte Differentiation
2008
Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance
2013
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Regulatory circuits controlling white versus brown adipocyte differentiation
2006
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity
2016
Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance
2011
The Role of Adipocyte XBP1 in Metabolic Regulation during Lactation
2013
CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice
2017
PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
2007
Huntington's disease: from pathology and genetics to potential therapies
2008
Mitochondrial-Nuclear Communications
2007
Activity-Dependent Signaling Pathways Controlling Muscle Diversity and Plasticity
2007
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD
2016
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
PGC-1α Coactivates PDK4 Gene Expression via the Orphan Nuclear Receptor ERRα: a Mechanism for Transcriptional Control of Muscle Glucose Metabolism
2005
Once-Weekly Semaglutide in Adults with Overweight or Obesity
2021 Standout
Spermidine in health and disease
2018 StandoutScience
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6
2011
Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum
2012
“Deficiency” of Mitochondria in Muscle Does Not Cause Insulin Resistance
2013
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Mitochondrial dysfunction and insulin resistance: an update
2014
Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?
2015
Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Expression
2009
The Impact of Macrophage Insulin Resistance on Advanced Atherosclerotic Plaque Progression
2010
Works of Zhouji Chen being referenced
PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner
2013
Glucose Transporter 8 (GLUT8) Mediates Fructose-induced de Novo Lipogenesis and Macrosteatosis
2014
Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice
2009
A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation
2006
Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity
2010
Diminished Hepatic Gluconeogenesis via Defects in Tricarboxylic Acid Cycle Flux in Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α)-deficient Mice
2006
Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway
2006
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
2012
A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele
2015
PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis
2005
Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice
2014
Lipin 2 Is a Liver-enriched Phosphatidate Phosphohydrolase Enzyme That Is Dynamically Regulated by Fasting and Obesity in Mice
2009
A Targeted Apolipoprotein B-38.9-producing Mutation Causes Fatty Livers in Mice Due to the Reduced Ability of Apolipoprotein B-38.9 to Transport Triglycerides
2000
Association Between Specific Adipose Tissue CD4+ T-Cell Populations and Insulin Resistance in Obese Individuals
2013
Hypobetalipoproteinemic Mice with a Targeted Apolipoprotein (Apo) B-27.6-specifying Mutation
2002
Reduced intestinal fat absorptive capacity but enhanced susceptibility to diet-induced fatty liver in mice heterozygous for ApoB38.9 truncation
2005
Hepatic Fatty Acid Synthesis Is Suppressed in Mice With Fatty Livers Due to Targeted Apolipoprotein B38.9 Mutation
2002
Fatty liver and insulin resistance: not always linked.
2008
1,25(OH) 2 Vitamin D Inhibits Foam Cell Formation and Suppresses Macrophage Cholesterol Uptake in Patients With Type 2 Diabetes Mellitus
2009
Alterations in Hepatic Metabolism in fld Mice Reveal a Role for Lipin 1 in Regulating VLDL-Triacylglyceride Secretion
2008
Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
2014
Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis
2016
IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis
2012