Citation Impact
Citing Papers
Consistent blind protein structure generation from NMR chemical shift data
2008 StandoutNobel
Cell entry mechanisms of SARS-CoV-2
2020 Standout
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB Signaling
2009
Flavivirus Replication Complex Assembly Revealed by DNAJC14 Functional Mapping
2012 StandoutNobel
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
2008
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
2020 StandoutScience
Origin and evolution of pathogenic coronaviruses
2018 Standout
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets
2015
Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems
2017 StandoutNobel
The yin and yang of viruses and interferons
2012
Coronavirus biology and replication: implications for SARS-CoV-2
2020 Standout
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Mechanisms of SARS-CoV-2 entry into cells
2021 Standout
Coronaviruses post-SARS: update on replication and pathogenesis
2009
SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism
2010
Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
2017
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Host Factors in Coronavirus Replication
2017
SARS and MERS: recent insights into emerging coronaviruses
2016 Standout
Coronavirus infection, ER stress, apoptosis and innate immunity
2014
Antiviral activities of ISG20 in positive-strand RNA virus infections
2010
Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology
2017 Standout
Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
2020 Standout
Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication
2010
Coronaviruses — drug discovery and therapeutic options
2016
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum
2008
SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon
2012
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
2014
Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8)
2006
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Cytosolic Sensing of Viruses
2013
Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways
2015
Recent insights into the complexity of Tank‐binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1
2013
Interferon-induced ISG15 pathway: an ongoing virus–host battle
2013
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
2016
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles
2008
High incidence of ubiquitin‐like domains in human ubiquitin‐specific proteases
2007
Clinical and immunological features of severe and moderate coronavirus disease 2019
2020 Standout
MERS-CoV spike protein: Targets for vaccines and therapeutics
2016
Characterization of ubiquitin and ubiquitin‐like‐protein isopeptidase activities
2008
Qualitative and quantitative ultrastructural analysis of the membrane rearrangements induced by coronavirus
2010
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
2020 Standout
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus
2008
Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records
2020 Standout
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
The trinity of COVID-19: immunity, inflammation and intervention
2020 Standout
Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19
2020 Standout
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
2020 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Coronavirus Pathogenesis
2011
Regulation of type I interferon responses
2013 Standout
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
2020 Standout
Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19
2020
Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo
2008
Infection with MERS-CoV Causes Lethal Pneumonia in the Common Marmoset
2014
The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
2013
Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants
2017
Ovarian Tumor Domain-Containing Viral Proteases Evade Ubiquitin- and ISG15-Dependent Innate Immune Responses
2007
Nidovirales: Evolving the largest RNA virus genome
2006
Autophagy in immunity and inflammation
2011 StandoutNature
Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3
2017
Structural basis of receptor recognition by SARS-CoV-2
2020 StandoutNature
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
ATP-Dependent Effector-like Functions of RIG-I-like Receptors
2015 StandoutNobel
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response
2016
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Pfam: The protein families database in 2021
2020 Standout
The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection
2016
Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display different interferon antagonist activities
2011
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)
2020 Standout
Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling
2019
Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain
2012
Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology
2015
Viral evasion and subversion of pattern-recognition receptor signalling
2008
Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes)
2008
Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells
2008
Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells
2015
Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance
2016 StandoutNobel
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV
2020
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle
2010
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Genomic Characterization of Severe Acute Respiratory Syndrome-Related Coronavirus in European Bats and Classification of Coronaviruses Based on Partial RNA-Dependent RNA Polymerase Gene Sequences
2010
Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease
2020
Mechanisms of Severe Acute Respiratory Syndrome Pathogenesis and Innate Immunomodulation
2008
Hepatitis E Virus Inhibits Type I Interferon Induction by ORF1 Products
2014
From SARS to MERS : crystallographic studies on coronaviral proteases enable antiviral drug design
2014
A molecular pore spans the double membrane of the coronavirus replication organelle
2020 Science
Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles
2013
Inflammatory Mechanisms in Obesity
2011 Standout
MERS-CoV spike protein: a key target for antivirals
2016
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
2009
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20
2018 StandoutNobel
A Novel Coronavirus from Patients with Pneumonia in China, 2019
2020 Standout
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication
2017
Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design
2020
Novel β-Barrel Fold in the Nuclear Magnetic Resonance Structure of the Replicase Nonstructural Protein 1 from the Severe Acute Respiratory Syndrome Coronavirus
2007 Nobel
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3
2016
Drug Development and Medicinal Chemistry Efforts toward SARS‐Coronavirus and Covid‐19 Therapeutics
2020
The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling
2014
Coronavirus Infections—More Than Just the Common Cold
2020 Standout
La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
2020 Standout
Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation
2006
Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages
2020
Works of Zhongbin Chen being referenced
Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus
2007
p53 Degradation by a Coronavirus Papain-like Protease Suppresses Type I Interferon Signaling
2014
SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex
2014
Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity
2014
Membrane topology of murine coronavirus replicase nonstructural protein 3
2007
Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling
2012
Deubiquitinating Activity of the SARS-CoV Papain-Like Protease
2006
The Leader Proteinase of Foot-and-Mouth Disease Virus Negatively Regulates the Type I Interferon Pathway by Acting as a Viral Deubiquitinase
2011
Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease
2013
Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases
2010
Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression
2008
The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase
2013
The Papain-Like Protease of Severe Acute Respiratory Syndrome Coronavirus Has Deubiquitinating Activity
2005
Proteolytic Processing and Deubiquitinating Activity of Papain-Like Proteases of Human Coronavirus NL63
2007