Citation Impact
Citing Papers
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac
2015 Science
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana
2021 StandoutNobel
Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension
2015
Activation of the mechanosensitive ion channel MscL by mechanical stimulation of supported Droplet-Hydrogel bilayers
2017
Piezo1 ion channel pore properties are dictated by C-terminal region
2015 StandoutNobel
Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension
2016
Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D
2016
Piezo1 Channels Are Inherently Mechanosensitive
2016 StandoutNobel
Functional Role for Piezo1 in Stretch-evoked Ca2+ Influx and ATP Release in Urothelial Cell Cultures
2014
Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel
2017
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Molecular force transduction by ion channels – diversity and unifying principles
2012
Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
2013 StandoutNature
Stressed podocytes—mechanical forces, sensors, signaling and response
2017
The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels
2016
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Structure of the mechanosensitive OSCA channels
2018
Force-induced conformational changes in PIEZO1
2019 NatureNobel
Spectator no more, the role of the membrane in regulating ion channel function
2016
Physiology of Cell Volume Regulation in Vertebrates
2009
Pore region of TRPV3 ion channel is specifically required for heat activation
2008 StandoutNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Revisiting TRPC1 and TRPC6 mechanosensitivity
2007
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Sensory mechanotransduction at membrane-matrix interfaces
2014
Structures of TRPV2 in distinct conformations provide insight into role of the pore turret
2018
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Mechanically Activated Ion Channels
2015 StandoutNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Structural Designs and Mechanogating Mechanisms of the Mechanosensitive Piezo Channels
2021
Dynamical features of thePlasmodium falciparumribosome during translation
2015 StandoutNobel
Biophysical Principles of Ion-Channel-Mediated Mechanosensory Transduction
2019
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
“Force-from-lipids” gating of mechanosensitive channels modulated by PUFAs
2017
The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements
2014
Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel
2015
Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes
2014
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Mammalian Mechanoelectrical Transduction: Structure and Function of Force-Gated Ion Channels
2019
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels
2014
Mechanosensitive TRP channels in cardiovascular pathophysiology
2009
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Tuning ion channel mechanosensitivity by asymmetry of the transbilayer pressure profile
2018
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Touch, Tension, and Transduction – The Function and Regulation of Piezo Ion Channels
2016
Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
2014 NatureNobel
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interface
2012
Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
2010 StandoutNobel
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
Identification and Analysis of Putative Homologues of Mechanosensitive Channels in Pathogenic Protozoa
2013
A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating
2008 StandoutNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization
2017 StandoutNobel
The role of lipids in mechanosensation
2015
De novo protein structure determination from near-atomic-resolution cryo-EM maps
2015 StandoutNobel
Mechanosensitive TRPC1 Channels Promote Calpain Proteolysis of Talin to Regulate Spinal Axon Outgrowth
2013
Neurosensory mechanotransduction
2008 StandoutNobel
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms
2020
Quantifying the Dynamics of Protein Self-Organization Using Deep Learning Analysis of Atomic Force Microscopy Data
2020 StandoutNobel
Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes
2017
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier
2019 Nobel
Bacterial Mechanosensors
2017
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Trajectories of the ribosome as a Brownian nanomachine
2014 StandoutNobel
Feeling Force: Physical and Physiological Principles Enabling Sensory Mechanotransduction
2015
Feeling the hidden mechanical forces in lipid bilayer is an original sense
2014
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Mammalian TRP ion channels are insensitive to membrane stretch
2019
Asymmetric mechanosensitivity in a eukaryotic ion channel
2017
The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1
2010
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel
2012
OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels
2018 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2
2015
Multiple Unbiased Prospective Screens Identify TRP Channels and Their Conserved Gating Elements
2008 StandoutNobel
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes
2015
Comparative sequence analysis suggests a conserved gating mechanism for TRP channels
2015
Works of Zhenwei Su being referenced
The use of yeast to understand TRP-channel mechanosensitivity
2009
Hypotonic shocks activate rat TRPV4 in yeast in the absence of polyunsaturated fatty acids
2009
Indole and other aromatic compounds activate the yeast TRPY1 channel
2008
Increased Basal Activity Is a Key Determinant in the Severity of Human Skeletal Dysplasia Caused by TRPV4 Mutations
2011
Forward Genetic Analysis Reveals Multiple Gating Mechanisms of TRPV4
2010
Wild-type and Brachyolmia-causing Mutant TRPV4 Channels Respond Directly to Stretch Force
2010
The core domain as the force sensor of the yeast mechanosensitive TRP channel
2011
Yeast gain-of-function mutations reveal structure–function relationships conserved among different subfamilies of transient receptor potential channels
2007
Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K + channels
2014 Nobel
Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate
2007