Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF
2001 StandoutScience
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
The Essential Role of the Intestinal Microbiota in Facilitating Acute Inflammatory Responses
2004
The Required Role of Endogenously Produced Lipoxin A4 and Annexin-1 for the Production of IL-10 and Inflammatory Hyporesponsiveness in Mice
2007
NKT Cell Activation Mediates Neutrophil IFN-γ Production and Renal Ischemia-Reperfusion Injury
2007
Role of hypoxia-inducible factor in cell survival during myocardial ischemia–reperfusion
2008
Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing
2013
Neutralization of Interleukin-18 Ameliorates Ischemia/Reperfusion-induced Myocardial Injury
2009
The DNA-damage response in human biology and disease
2009 StandoutNature
A2B adenosine receptor dampens hypoxia-induced vascular leak
2007
Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11βHSD1-deficient mice post-MI
2010
Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1
2004
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Toll-like receptor 4 deficiency: Smaller infarcts, but nogain in function
2007
Resistance to Acute Septic Peritonitis in Poly(ADP-ribose) Polymerase-1-Deficient Mice
2002
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
2004 StandoutNobel
Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1
2000 StandoutNobel
Cardiac-specific blockade of NF-κB in cardiac pathophysiology: differences between acute and chronic stimuli in vivo
2005
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Preconditioning: a paradigm shift in the biology of myocardial ischemia
2006
Protective responses in the ischemic myocardium
2000
Nucleotide signalling during inflammation
2014 StandoutNature
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Use of a hanging-weight system for isolated renal artery occlusion during ischemic preconditioning in mice
2006
Targeted Deletion of the A3Adenosine Receptor Confers Resistance to Myocardial Ischemic Injury and does not Prevent Early Preconditioning
2001
Activation of invariant natural killer T cells by α-galactosylceramide ameliorates myocardial ischemia/reperfusion injury in mice
2013
Collagen‐Targeted MRI Contrast Agent for Molecular Imaging of Fibrosis
2007
Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia‐reperfusion injury and preconditioning
2003
Adenosine receptors as therapeutic targets
2006 Standout
A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs
2002
Endothelial protective effects of preconditioning
2002
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
2004 StandoutNature
Targeting iNKT cells for the treatment of sickle cell disease
2011
Tumor necrosis factor receptor 2 signaling limits β-adrenergic receptor-mediated cardiac hypertrophy in vivo
2011
Purinergic regulation of the immune system
2016
Impaired Infarct Healing in Atherosclerotic Mice With Ly-6ChiMonocytosis
2010
Ca2+/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
2004 StandoutNobel
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
Targeting the Chemokines in Cardiac Repair
2014
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
NF-κB activation by reactive oxygen species: Fifteen years later
2006
Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development
2008
Physiological aspects of high-altitude pulmonary edema
2005
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure
2002
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Oxidative stress and regional ischemia-reperfusion injury: the peroxynitrite–poly(ADP-ribose) polymerase connection
2003
Poly(ADP-ribose) polymerase activation in the reperfused myocardium
2004
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo
2006
Peroxynitrite Is a Potent Inhibitor of NF-κB Activation Triggered by Inflammatory Stimuli in Cardiac and Endothelial Cell Lines
2005
The A3 adenosine receptor: An enigmatic player in cell biology
2007
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Cell Grafting for Cardiac Repair
2003
Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia
2009
Activation of Poly(ADP-Ribose) Polymerase Contributes to Development of Doxorubicin-Induced Heart Failure
2002
Remote ischemic preconditioning confers late protection against myocardial ischemia–reperfusion injury in mice by upregulating interleukin-10
2012
Mechanisms of the anti‐inflammatory effects of the natural secosteroids physalins in a model of intestinal ischaemia and reperfusion injury
2005
Ultrabright organic dots with aggregation-induced emission characteristics for cell tracking
2014
Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
2001 StandoutNobel
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders
2002
Systematic evaluation of a novel model for cardiac ischemic preconditioning in mice
2006
Anti-Inflammatory Strategies for Ventricular Remodeling Following ST-Segment Elevation Acute Myocardial Infarction
2014
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
2002 StandoutNobel
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
2008 Standout
Adenosine, an endogenous distress signal, modulates tissue damage and repair
2007
The Cross-Species A3Adenosine-Receptor Antagonist MRS 1292 Inhibits Adenosine-Triggered Human Nonpigmented Ciliary Epithelial Cell Fluid Release and Reduces Mouse Intraocular Pressure
2005
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Use of a hanging-weight system for liver ischemic preconditioning in mice
2008
Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart
2008
Structure of Factor-inhibiting Hypoxia-inducible Factor (HIF) Reveals Mechanism of Oxidative Modification of HIF-1α
2003 StandoutNobel
Novel phenanthridinone inhibitors of poly(adenosine 5′-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents*
2002
Role of nitric oxide and oxidative stress in ischaemic myocardial injury and preconditioning
2003
Adenosine A1 receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia
2004
Selection of Mutant CHO Cells with Constitutive Activation of the HIF System and Inactivation of the von Hippel-Lindau Tumor Suppressor
2001 StandoutNobel
Tissue-Specific Effects of the Nuclear Factor κB Subunit p50 on Myocardial Ischemia-Reperfusion Injury
2007
Hypoxia-inducible Factor-1 Deficiency Results in Dysregulated Erythropoiesis Signaling and Iron Homeostasis in Mouse Development
2006 StandoutNobel
The ubiquitous role of nitric oxide in cardioprotection
2005
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling
2006
Role of Poly(ADP‐ribose) polymerase 1 (PARP‐1) in Cardiovascular Diseases: The Therapeutic Potential of PARP Inhibitors
2007
Modulation of Glucocorticoid Receptor Function via Phosphorylation
2004
The Reno-Vascular A2B Adenosine Receptor Protects the Kidney from Ischemia
2008
Targeting eNOS for stroke protection
2004
Shaping of monocyte and macrophage function by adenosine receptors
2006
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
Activator protein‐1 signalling pathway and apoptosis are modulated by poly(ADP‐ribose) polymerase‐1 in experimental colitis
2004
Purinergic Signaling during Inflammation
2012
Activation of A3 Adenosine Receptor Provides Lung Protection Against Ischemia-Reperfusion Injury Associated with Reduction in Apoptosis
2004
Of Mice and Dogs
2004
Attenuating myocardial ischemia by targeting A2B adenosine receptors
2013
Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways in colitis
2003
Fluorescent Indicators for Akt/Protein Kinase B and Dynamics of Akt Activity Visualized in Living Cells
2003
NF-κB driven cardioprotective gene programs; Hsp70.3 and cardioprotection after late ischemic preconditioning
2010
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
2016
Poly(adenosine 5′-diphosphate) ribose polymerase activation as a cause of metabolic dysfunction in critical illness
2002
Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto‐optical nanoparticle
2005
CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia/Reperfusion Injury
2007
Extracellular Adenosine: A Safety Signal That Dampens Hypoxia-Induced Inflammation During Ischemia
2010
Novel Role of NADPH Oxidase in Angiogenesis and Stem/Progenitor Cell Function
2009
Therapeutic Anti-Inflammatory Effects of Myeloid Cell Adenosine Receptor A2a Stimulation in Lipopolysaccharide-Induced Lung Injury
2007
Adenosine: An Old Drug Newly Discovered
2009
Overexpression of A3 adenosine receptors decreases heart rate, preserves energetics, and protects ischemic hearts
2002
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
ACTIONS OF ADENOSINE AT ITS RECEPTORS IN THE CNS: Insights from Knockouts and Drugs
2004
Cardioprotection by Ecto-5′-Nucleotidase (CD73) and A 2B Adenosine Receptors
2007
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury
2010
Targeted deletion of adenosine A3receptors augments adenosine-induced coronary flow in isolated mouse heart
2002
Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
2008 Standout
The Role of Poly(ADP-Ribose) Polymerase Activation in the Development of Myocardial and Endothelial Dysfunction in Diabetes
2002
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation
2006
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Regulation of the Inflammatory Response in Cardiac Repair
2012
Activation of CD4 + T Lymphocytes Improves Wound Healing and Survival After Experimental Myocardial Infarction in Mice
2012
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging
2002
Foxp3+CD4+T Cells Improve Healing After Myocardial Infarction by Modulating Monocyte/Macrophage Differentiation
2014
Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse
2015
Cutting Edge: IL-1α Is a Crucial Danger Signal Triggering Acute Myocardial Inflammation during Myocardial Infarction
2014
The Late Phase of Preconditioning
2000
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease
2010
Central role of Sp1-regulated CD39 in hypoxia/ischemia protection
2008
Evidence that NOS2 acts as a trigger and mediator of late preconditioning induced by acute systemic hypoxia
2002
Knockout of A3 adenosine receptors reduces mouse intraocular pressure.
2002
HIF-1–dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
2008
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Potent Metalloporphyrin Peroxynitrite Decomposition Catalyst Protects Against the Development of Doxorubicin-Induced Cardiac Dysfunction
2003
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury
2003 StandoutNobel
Nitric Oxide and Cardiac Function
2003
Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow–derived cells or deletion of the A2A receptor on non-bone marrow–derived cells
2006
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Dehydroepiandrosterone Mimics Acute Actions of Insulin to Stimulate Production of Both Nitric Oxide and Endothelin 1 via Distinct Phosphatidylinositol 3-Kinase- and Mitogen-Activated Protein Kinase-Dependent Pathways in Vascular Endothelium
2005
Cellular and Molecular Dissection of Reperfusion Injury
2000 StandoutNobel
Role of tissue kallikrein in the cardioprotective effects of ischemic and pharmacological preconditioning in myocardial ischemia
2005
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Renal Ischemia-Reperfusion Injury and Adenosine 2A Receptor-Mediated Tissue Protection: The Role of CD4+ T Cells and IFN-γ
2006
Gene Dosage-Dependent Effects of Cardiac-Specific Overexpression of the A 3 Adenosine Receptor
2002
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
2002
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase
2000
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Nonnuclear Actions of Estrogen
2002
A3adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure
2003
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Works of Zequan Yang being referenced
Absence of endogenous interleukin 10 enhances early stress response during post-ischaemic injury in mice intestine
2001
Borderzone Contractile Dysfunction Is Transiently Attenuated and Left Ventricular Structural Remodeling Is Markedly Reduced Following Reperfused Myocardial Infarction in Inducible Nitric Oxide Synthase Knockout Mice
2007
Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia–reperfusion injury
2009
Effect of modulating cardiac A1adenosine receptor expression on protection with ischemic preconditioning
2005
Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle
2005
Activated platelets contribute importantly to myocardial reperfusion injury
2005
MR tagging early after myocardial infarction in mice demonstrates contractile dysfunction in adjacent and remote regions
2002
NADPH Oxidase in Bone Marrow–Derived Cells Mediates Pulmonary Ischemia-Reperfusion Injury
2008
Serial MRI evaluation of cardiac structure and function in mice after reperfused myocardial infarction
2002
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
2002
EFFECT OF GENETIC DISRUPTION OF POLY (ADP-RIBOSE) SYNTHETASE ON DELAYED PRODUCTION OF INFLAMMATORY MEDIATORS AND DELAYED NECROSIS DURING MYOCARDIAL ISCHEMIA-REPERFUSION INJURY
2000
The infarct-sparing effect of IB-MECA against myocardial ischemia/reperfusion injury in mice is mediated by sequential activation of adenosine A3 and A2A receptors
2015
Crucial Role of Endogenous Interleukin-10 Production in Myocardial Ischemia/Reperfusion Injury
2000
Demonstration of an early and a late phase of ischemic preconditioning in mice
1998
Simultaneous Evaluation of Infarct Size and Cardiac Function in Intact Mice by Contrast-Enhanced Cardiac Magnetic Resonance Imaging Reveals Contractile Dysfunction in Noninfarcted Regions Early After Myocardial Infarction
2004
Targeted deletion of A3adenosine receptors improves tolerance to ischemia-reperfusion injury in mouse myocardium
2001
Absence of inducible nitric oxide synthase modulates early reperfusion‐induced NF‐κB and AP‐1 activation and enhances myocardial damage
2002
Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction
2002
A1or A3Adenosine Receptors Induce Late Preconditioning Against Infarction in Conscious Rabbits by Different Mechanisms
2001
Myocardial Infarct–Sparing Effect of Adenosine A2AReceptor Activation Is due to Its Action on CD4+T Lymphocytes
2006
Infarct-Sparing Effect of A 2A -Adenosine Receptor Activation Is Due Primarily to Its Action on Lymphocytes
2005
Noninvasive Tracking of Cardiac Embryonic Stem Cells In Vivo Using Magnetic Resonance Imaging Techniques
2007
Myocardial Ischemic Preconditioning in Rodents Is Dependent on Poly (ADP-Ribose) Synthetase
2001
The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene
1999