Citation Impact
Citing Papers
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
2001 Standout
Glucose Generates Sub-plasma Membrane ATP Microdomains in Single Islet β-Cells
1999
Glucagon-like Peptide-1 Receptor Signaling Modulates β Cell Apoptosis
2002
Mechanised nanoparticles for drug delivery
2009 StandoutNobel
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
2008
AMPK, the metabolic syndrome and cancer
2005
Insulin Secretion, DNA Damage, and Apoptosis in Human and Rat Islets of Langerhans Following Exposure to Nitric Oxide, Peroxynitrite, and Cytokines
1998
Minireview: Glucagon-Like Peptides Regulate Cell Proliferation and Apoptosis in the Pancreas, Gut, and Central Nervous System
2004
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Mitochondrial function in normal and diabetic β-cells
2001 Nature
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
AMPK alterations in cardiac physiology and pathology: enemy or ally?
2006
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
2009
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes
2007 Standout
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase
2005
Type 2 diabetes as an inflammatory disease
2011 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
2008 StandoutNature
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
The role of gut hormones in glucose homeostasis
2007
Glycemic Durability of Rosiglitazone, Metformin, or Glyburide Monotherapy
2006 Standout
Biology of Incretins: GLP-1 and GIP
2007 Standout
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction
2003
Glucagon-like peptide 1(GLP-1) in biology and pathology
2005
Microfluidic organs-on-chips
2014 Standout
Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes
2015 Standout
AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms
2004
International Union of Pharmacology. XXXV. The Glucagon Receptor Family
2003
Type 1 diabetes
2013 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Quantitative Subcellular Imaging of Glucose Metabolism within Intact Pancreatic Islets
1996
The Physiology of Glucagon-like Peptide 1
2007 Standout
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
2009 Standout
Sensitivity of human pancreatic islets to peroxynitrite‐induced cell dysfunction and death
1996
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Sulforaphane protects against cytokine- and streptozotocin-induced β-cell damage by suppressing the NF-κB pathway
2008
β-Cell death during progression to diabetes
2001 Nature
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
2015 Standout
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
2002 StandoutNobel
Pancreatic islet inflammation in type 2 diabetes: From α and β cell compensation to dysfunction
2009
Metabolic fuel selection: general integration at the whole-body level
1995
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
2008 Standout
The major glucagon-like peptide-1 metabolite, GLP-1-(9–36)-amide, does not affect glucose or insulin levels in mice
2004
Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors
2011 StandoutNobel
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
2008 Standout
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
2003 Standout
Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion
2008
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling
2007
Persistent Improvement of Type 2 Diabetes in the Goto-Kakizaki Rat Model by Expansion of the β-Cell Mass During the Prediabetic Period With Glucagon-Like Peptide-1 or Exendin-4
2002
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells
2005
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Diverse Cytopathologies in Mitochondrial Disease Are Caused by AMP-activated Protein Kinase Signaling
2007
β-Cell Pdx1 Expression Is Essential for the Glucoregulatory, Proliferative, and Cytoprotective Actions of Glucagon-Like Peptide-1
2005
Type 2 diabetes: principles of pathogenesis and therapy
2005 Standout
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction
2003
AMP-Activated Protein Kinase as a Drug Target
2006
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors
2004
Nitric oxide and the immune response
2001 Standout
Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
2003 Standout
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties
2003
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Glucose-induced pulsatile insulin release from single islets at stable and oscillatory cytoplasmic Ca2+
1998
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells
2002
Development of Autoimmune Diabetes in NOD Mice Is Associated With the Formation of Peroxynitrite in Pancreatic Islet β-Cells
1997
Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles
2002 StandoutScience
Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
2002
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Cardiac Function in Mice Lacking the Glucagon-Like Peptide-1 Receptor
2003
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis
2003
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.
1995
Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca2+ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K+ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets
2004
Mechanisms of Diabetic Complications
2013 Standout
The DisGeNET knowledge platform for disease genomics: 2019 update
2019 Standout
Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1)
2006
Inducible nitric oxide synthase in human diseases
1998
Engineering and Material Considerations in Islet Cell Transplantation
1999
Cytokines Induce Deoxyribonucleic Acid Strand Breaks and Apoptosis in Human Pancreatic Islet Cells*
1997
Development and Characterization of a Glucagon-Like Peptide 1-Albumin Conjugate
2003
Glucagon-Like Peptides: Regulators of Cell Proliferation, Differentiation, and Apoptosis
2003
Long-Term AICAR Administration and Exercise Prevents Diabetes in ZDF Rats
2005
Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems
2012 Standout
Thiazolidinedione Use, Fluid Retention, and Congestive Heart Failure
2003
Heme Oxygenase-1 Induction in Islet Cells Results in Protection From Apoptosis and Improved In Vivo Function After Transplantation
2001
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
2003 Standout
Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential
2005
Works of Z. Ling being referenced
Prolonged exposure of pancreatic beta cells to raised glucose concentrations results in increased cellular content of islet amyloid polypeptide precursors
1999
Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells
1994
Glucagon-like peptide 1 receptor signaling influences topography of islet cells in mice
2001
Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipient characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft
1998
Physiologic relevance of heterogeneity in the pancreatic beta-cell population
1994
AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase
2003
Glucagon receptors on human islet cells contribute to glucose competence of insulin release
2000
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.
1994
Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.
2000
Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells
1996