Citation Impact
Citing Papers
Hallmarks of Cancer: The Next Generation
2011 Standout
Identification of a major co-receptor for primary isolates of HIV-1
1996 StandoutNature
Chemokine Networks and Breast Cancer Metastasis
2007
Turning on the respiratory burst
1990
Inflammation and cancer
2002 StandoutNature
Receptor Recognition and Specificity of Interleukin-8 Is Determined by Residues That Cluster Near a Surface-accessible Hydrophobic Pocket
1996
Monocyte Chemotactic Protein-3 (MCP3) Interacts with Multiple Leukocyte Receptors
1995
Chemokines and leukocyte traffic
1998 StandoutNature
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
Inositol phosphates and cell signalling
1989 StandoutNature
Cloning and Functional Expression of a Human Eosinophil CC Chemokine Receptor
1995
The Orphan Mouse Receptor Interleukin (IL)-8Rβ Binds N51
1995
Beyond Cholesterol
1989 Standout
Involvement of chemokine receptors in breast cancer metastasis
2001 StandoutNature
Regulation of calcium influx by second messengers in rat mast cells
1988 StandoutNatureNobel
Signals and Receptors Involved in Recruitment of Inflammatory Cells
1995
Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
1990 StandoutNobel
Exchanging Interleukin-8 and Melanoma Growth-stimulating Activity Receptor Binding Specificities
1996
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
CXC Chemokines Bind to Unique Sets of Selectivity Determinants That Can Function Independently and Are Broadly Distributed on Multiple Domains of Human Interleukin-8 Receptor B
1996
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
1998 StandoutNature
Chemokine receptors: Structure, function and role in microbial pathogenesis
1996
N51 Competes 125I-Interleukin (IL)-8 Binding to IL-8Rβ but Not IL-8Rα
1995
Chemotaxis in Eukaryotic Cells: A Focus on Leukocytes and Dictyostelium
1988
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
Neutrophil thrombospondin receptors are linked to GTP-binding proteins
1996 StandoutNobel
The role of cytokines in the epithelial cancer microenvironment
2002
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
Chemokines in cancer
2002
Determination of the monomer-dimer equilibrium of interleukin-8 reveals it is a monomer at physiological concentrations
1994
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Inflammation and the development of pancreatic cancer
2002
KSHV-GPCR and CXCR2 transforming capacity and angiogenic responses are mediated through a JAK2-STAT3-dependent pathway
2005
An inositol tetrakisphosphate-containing phospholipid in activated neutrophils
1988 Nature
Characterization of the membrane‐associated GTPase activity: Effects of chemotactic factors and toxins
1989
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
1994 Standout
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
1997 StandoutNatureNobel
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
1996 StandoutNature
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
1996 StandoutNature
Receptor Up-regulation, Internalization, and Interconverting Receptor States
1996
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Mutagenesis Studies of Interleukin-8
1996
Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION
1974
Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens.
1977 StandoutNobel
Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors.
1992 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process.
1979
Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex
1975 StandoutNatureNobel
CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1
1996 StandoutScience
Regulation of nuclear factor kappaB activation by G-protein-coupled receptors.
2001
Receptor-operated Ca channels
1987 StandoutNatureNobel
Receptor-cytoskeleton interactions and membrane traffic may regulate chemoattractant-induced superoxide production in human granulocytes.
1986
Disorders of Phagocyte Function
1987
Chemoattractant-stimulated GTPase activity is decreased on membranes from polymorphonuclear leukocytes incubated in chemoattractant
1989
Regulation of immune response to tumor antigen: interference with syngeneic tumor immunity by anti-IA alloantisera.
1979 StandoutNobel
Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration
1986 Nature
Octyl glucoside extracts GTP-binding regulatory proteins from rat brain "synaptoneurosomes" as large, polydisperse structures devoid of beta gamma complexes and sensitive to disaggregation by guanine nucleotides.
1990 StandoutNobel
IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways
2001
The Interleukin-8 Pathway in Cancer
2008 Standout
IL-8-Mediated Cell Migration in Endothelial Cells Depends on Cathepsin B Activity and Transactivation of the Epidermal Growth Factor Receptor
2003
The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils
1981
CXC chemokines in angiogenesis
2000
Arachidonic acid metabolism in polymorphonuclear leukocytes
1979 StandoutNobel
Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues.
1995
Human Chemokines: An Update
1997 Standout
Cell-Mediated Cytotoxicity, Allograft Rejection, and Tumor Immunity
1974 Standout
Two transduction sequences are necessary for neutrophil activation by receptor agonists.
1988
Quantitative changes in inositol 1,4,5-trisphosphate in chemoattractant-stimulated neutrophils.
1986
Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils
1989
Active Oxygen Species in the Induction of Plant Systemic Acquired Resistance by Salicylic Acid
1993 StandoutScience
Is Cytosolic Ionized Calcium Regulating Neutrophil Activation?
1983 StandoutScienceNobel
Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase
1985 StandoutNature
β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6
1999 StandoutScience
Relationship of actin polymerization and depolymerization to light scattering in human neutrophils: dependence on receptor occupancy and intracellular Ca++.
1985
Structure/activity analysis of human monocyte chemoattractant protein-1 (MCP-1) by mutagenesis. Identification of a mutated protein that inhibits MCP-1-mediated monocyte chemotaxis.
1994
Receptor class desensitization of leukocyte chemoattractant receptors.
1991
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases
1976 StandoutNobel
Regulation of nuclear factor κB activation by G-protein-coupled receptors
2001
The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha.
2000
Endocytic vesicles from renal papilla which retrieve the vasopressin-sensitive water channel do not contain a functional H+ ATPase.
1990
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Regulation of the affinity state of the N-formylated peptide receptor of neutrophils: role of guanine nucleotide-binding proteins and the cytoskeleton.
1987
HIV replication in CD4+T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous β-chemokines and the viral inductive effects of other endogenous cytokines
1996 StandoutNobel
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
The Biology and Detection of Immune Complexes
1980
Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways.
1991
Interleukin-8 Signaling Promotes Translational Regulation of Cyclin D in Androgen-Independent Prostate Cancer Cells
2007
Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by islet-activating protein, pertussis toxin. A possible role of the toxin substrate in Ca2+-mobilizing receptor-mediated signal transduction.
1985
Nonapical and Cytoplasmic Expression of Interleukin-8, CXCR1, and CXCR2 Correlates with Cell Proliferation and Microvessel Density in Prostate Cancer
2005
Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin
1984 StandoutNobel
A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS
1975 StandoutNobel
Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells.
1978 StandoutNobel
Antioxidant defenses and lipid peroxidation in human blood plasma.
1988 Standout
Chronic Lymphocytic Leukemia B Cells Express Functional CXCR4 Chemokine Receptors That Mediate Spontaneous Migration Beneath Bone Marrow Stromal Cells
1999
Works of Z G Oades being referenced
Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. Secretion of granule constituents and increased oxidation of glucose.
1975
Point Mutation Causing Constitutive Signaling of CXCR2 Leads to Transforming Activity Similar to Kaposi’s Sarcoma Herpesvirus-G Protein-Coupled Receptor
1999
Actin Polymerization, Calcium-Transients, and Phospholipid Metabolism in Human Neutrophils After Stimulation with Interleukin-8 and N-formyl Peptide
1994
The Role of Tyr13 and Lys15 of Interleukin-8 in the High Affinity Interaction with the Interleukin-8 Receptor Type A
1995
Importance of the Carboxy-Terminus of the CXCR2 for Signal Transduction
1998
Multiple sites on IL-8 responsible for binding to alpha and beta IL-8 receptors.
1993
Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor.
1985
Evidence for N‐formyl chemotactic peptide‐stimulated GTPase activity in human neutrophil homogenates
1984
Signal transduction and ligand-receptor dynamics in the neutrophil. Ca2+ modulation and restoration.
1985
The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil.
1984
Three States for the Formyl Peptide Receptor on Intact Cells
1989
Enhancement of Immunologically Induced Granule Exocytosis from Neutrophils by Cytochalasin B
1973
Autocrine Growth Effect of IL-8 and GRO?? on a Human Pancreatic Cancer Cell Line, Capan-1
2000
N-formylpeptide-receptor dynamics, cytoskeletal activation, and intracellular calcium response in human neutrophil cytoplasts.
1987
Fluoresceinated chemotactic peptide and high-affinity antifluorescein antibody as a probe of the temporal characteristics of neutrophil stimulation.
1981
Neutrophil degranulation detected by right angle light scattering: spectroscopic methods suitable for simultaneous analyses of degranulation or shape change, elastase release, and cell aggregation.
1984
Activation of platelets by platelet-activating factor (PAF) derived from IgE-sensitized basophils. II. The role of serine proteases, cyclic nucleotides, and contractile elements in PAF-induced secretion.
1976