Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
2010
Whole-genome resequencing reveals loci under selection during chicken domestication
2010 StandoutNature
Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
2011 Standout
Reactive oxygen species produced by NADPH oxidase regulate plant cell growth
2003 StandoutNature
Biochemical characterization of a Ca2+/NAD(P)H-dependent H2O2 generator in human thyroid tissue
1999
Vascular NADPH oxidases: molecular mechanisms of activation
2004
Identification of a Novel Partner of Duox
2004
Spironolactone exhibits direct renoprotective effects and inhibits renal renin–angiotensin–aldosterone system in diabetic rats
2008
Characterization of ThOX Proteins as Components of the Thyroid H2O2-Generating System
2002
Expression of functionally phagocyte‐type NAD(P)H oxidase in pericytes: effect of angiotensin II and high glucose
2005
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Transforming growth factor-β1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells
2005
Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes
2012
Redox regulation of Nox proteins
2010
Cellular mechanisms and treatment of diabetes vascular complications converge on reactive oxygen species
2005
Thyroid Oxidase (THOX2) Gene Expression in the Rat Thyroid Cell Line FRTL-5
2000
NOX4 as an oxygen sensor to regulate TASK-1 activity
2005
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Identification of Novel Genes Involved in Congenital Hypothyroidism Using Serial Analysis of Gene Expression
2003
Dual oxidase2 is expressed all along the digestive tract
2004
Ncf1 (p47phox) Is Essential for Direct Regulatory T Cell Mediated Suppression of CD4+ Effector T Cells
2011
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Angiotensin-(1–7) Prevents Activation of NADPH Oxidase and Renal Vascular Dysfunction in Diabetic Hypertensive Rats
2007
Uric Acid and Cardiovascular Risk
2008 Standout
Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism
2011
Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia
2005
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells
2006
Scleroderma
2009 Standout
Purification of a Novel Flavoprotein Involved in the Thyroid NADPH Oxidase
1999
Cellular and molecular mechanisms of renal fibrosis
2011 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Cloning of Two Human Thyroid cDNAs Encoding New Members of the NADPH Oxidase Family
2000
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
2012 Standout
Pigment epithelium-derived factor (PEDF) blocks angiotensin II signaling in endothelial cells via suppression of NADPH oxidase: a novel anti-oxidative mechanism of PEDF
2005
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
2011
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
New Insights into the Regulation of Epithelial–Mesenchymal Transition and Tissue Fibrosis
2012
Nitric oxide functions as a signal in plant disease resistance
1998 StandoutNature
The Nox Family of NAD(P)H Oxidases: Host Defense and Beyond
2004
NOD1 and NOD2 signalling links ER stress with inflammation
2016 StandoutNature
H2O2 activates Nox4 through PLA2‐dependent arachidonic acid production in adult cardiac fibroblasts
2005
Adiponectin regulates albuminuria and podocyte function in mice
2008
Metabolic Regulation by p53 Family Members
2013
Nox proteins in signal transduction
2009
Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
2013
The superoxide‐producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells
2005
Molecular composition and regulation of the Nox family NAD(P)H oxidases
2005
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
2019
Reactive oxygen species amplify glucose signalling in renal cells cultured under high glucose and in diabetic kidney
2005
Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
2007
EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis
2011
The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle
2004
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
2015 StandoutNobel
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Mechanisms and Functions of Inflammasomes
2014 Standout
Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications
2005
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
2011
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Targeting of the Dual Oxidase 2 N-terminal Region to the Plasma Membrane
2004
Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases
2005
Cytochrome P450: major player in reperfusion injury
2003
Obesity is associated with macrophage accumulation in adipose tissue
2003 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
2007
Ablation of the gene encoding p66Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation
2007
Cross talk between mitochondria and NADPH oxidases
2011
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
NADPH Oxidases in Cardiovascular Health and Disease
2006
NOX Enzymes and Pulmonary Disease
2009
Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress
2012
NADPH Oxidases in the Kidney
2006
ZO Proteins and Redox-Dependent Processes
2011
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
2010
Modulatory effects of HMG‐CoA reductase inhibitors in diabetic microangiopathy
2004
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Nitric oxide down‐regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells
2005
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
2000 StandoutNobel
Luminescent Chemodosimeters for Bioimaging
2012 Standout
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
2007
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes
2008
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches
2009
Non-Smad TGF-β signals
2005 Standout
Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes
2010
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
2010
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
2014 Standout
Redox Paradox
2005
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway
2007
The NADPH Oxidase Nox4 and Aging in the Heart
2010
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Mechanisms of Diabetic Complications
2013 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Reduction of Diabetes-Induced Oxidative Stress, Fibrotic Cytokine Expression, and Renal Dysfunction in Protein Kinase Cβ–Null Mice
2006
A Plant Homolog of the Neutrophil NADPH Oxidase gp91phox Subunit Gene Encodes a Plasma Membrane Protein with Ca2+ Binding Motifs
1998
Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus
2011
Identification of a Truncated Dual Oxidase 2 (DUOX2) Messenger Ribonucleic Acid (mRNA) in Two Rat Thyroid Cell Lines. Insulin and Forskolin Regulation of DUOX2 mRNA Levels in FRTL-5 Cells and Porcine Thyrocytes
2003
Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats
2010
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy
2006
Effect of Iodide on Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity and Duox2 Protein Expression in Isolated Porcine Thyroid Follicles
2003
Requirement for Rac1-Dependent NADPH Oxidase in the Cardiovascular and Dipsogenic Actions of Angiotensin II in the Brain
2004
Works of Yves Gorin being referenced
Subcellular localization of Nox4 and regulation in diabetes
2009
Nox4 NAD(P)H Oxidase Mediates Src-dependent Tyrosine Phosphorylation of PDK-1 in Response to Angiotensin II
2008
NAD(P)H Oxidases Regulate HIF-2α Protein Expression
2007
The NADPH Oxidase Subunit p22 Inhibits the Function of the Tumor Suppressor Protein Tuberin
2010
Angiotensin II stimulation of VEGF mRNA translation requires production of reactive oxygen species
2005
Solubilization and Characterization of a Thyroid Ca2+‐Dependent and NADPH‐Dependent K3Fe(CN)6 Reductase
1996
Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases
2011
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells
2003
PI 3 kinase-dependent Akt kinase and PKCε independently regulate interferon-γ-induced STAT1α serine phosphorylation to induce monocyte chemotactic protein-1 expression
2005
Involvement of Calcineurin in Transforming Growth Factor-β-mediated Regulation of Extracellular Matrix Accumulation
2004
NAD(P)H Oxidase Mediates TGF-β1–Induced Activation of Kidney Myofibroblasts
2009
Aiding and abetting roles of NOX oxidases in cellular transformation
2012
AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
2010
Inhibition of thyroid NADPH-oxidase by 2-iodohexadecanal in a cell-free system
1994
Nox4 NAD(P)H Oxidase Mediates Hypertrophy and Fibronectin Expression in the Diabetic Kidney
2005
The Ca2+- and reduced nicotinamide adenine dinucleotide phosphate-dependent hydrogen peroxide generating system is induced by thyrotropin in porcine thyroid cells.
1996
Regulation of the thyroid NADPH-dependent H2O2 generator by Ca2+: studies with phenylarsine oxide in thyroid plasma membrane
1997
Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells
2004
Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes
2011
ZΟ-1 Expression and Phosphorylation in Diabetic Nephropathy
2006
Mechanism of Oxidative DNA Damage in Diabetes
2008
Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox‐dependent pathway and independent of phosphoinositide 3‐kinase
2001