Standout Papers
Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Rationally engineered Cas9 nucleases with improved specificity
2015 StandoutScience
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity
2013
Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes
2010
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
To acquire or resist: the complex biological effects of CRISPR–Cas systems
2014
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
2013 Standout
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Not all predicted CRISPR–Cas systems are equal: isolated cas genes and classes of CRISPR like elements
2017
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
CRISPRDetect: A flexible algorithm to define CRISPR arrays
2016
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
Bacteria–phage coevolution as a driver of ecological and evolutionary processes in microbial communities
2014
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems
2013
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
metaSPAdes: a new versatile metagenomic assembler
2017 Standout
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Evolution and Ecology of CRISPR
2016
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
CRISPR-Cas Systems
2012
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Strain-Level Variation and Diverse Host Bacterial Responses in Episymbiotic Saccharibacteria
2022
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea
2013
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Rewriting a genome
2013 StandoutNatureNobel
Cultivation of a vampire: ‘ Candidatus Absconditicoccus praedator’
2021
Works of Yu‐Wei Wu being referenced
MaxBin: an automated binning method to recover individual genomes from metagenomes using an expectation-maximization algorithm
2014
SinicView: A visualization environment for comparisons of multiple nucleotide sequence alignment tools
2006
Diverse CRISPRs Evolving in Human Microbiomes
2012
A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l -tuples
2011
MaxBin 2.0: an automated binning algorithm to recover genomes from multiple metagenomic datasets
2015 Standout