Citation Impact
Citing Papers
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
Organic Synthesis—Where now?
1990
Electronic aspects of LADH catalytic mechanism
1991
Multiwfn: A multifunctional wavefunction analyzer
2011 Standout
Recent Progress in Direct Introduction of Fluorinated Groups on Alkenes and Alkynes by means of CH Bond Functionalization
2014
Dynamic personalities of proteins
2007 StandoutNature
Highly Enantioselective Hetero‐Diels–Alder Reaction of 1,3‐Bis(silyloxy)‐1,3‐dienes with Aldehydes Catalyzed by Chiral Disulfonimide
2012 StandoutNobel
Dynamic Covalent Chemistry
2002 StandoutNobel
Computer simulations of enzymatic reactions: examination of linear free-energy relationships and quantum-mechanical corrections in the initial proton-transfer step of carbonic anhydrase
1992 StandoutNobel
Insights into Enzyme Function from Studies on Mutants of Dihydrofolate Reductase
1988 Science
Modelling the catalytic reaction in human aldose reductase
1999
Computational prediction of small-molecule catalysts
2008 Nature
Camdas: An automated conformational analysis system using molecular dynamics
1997
Electrostatic Origin of the Catalytic Power of Enzymes and the Role of Preorganized Active Sites
1998 StandoutNobel
The Catalytic Asymmetric Knoevenagel Condensation
2011 StandoutNobel
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
2002 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Chivosazole A—Elucidation of the Absolute and Relative Configuration
2007
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
A Catalytic Asymmetric 6 π Electrocyclization: Enantioselective Synthesis of 2‐Pyrazolines
2009 StandoutNobel
The advent and development of organocatalysis
2008 StandoutNature
Enantioselective addition of diorganozincs to aldehydes catalyzed by β-amino alcohols
1990 StandoutNobel
Asymmetric 1,3-Dipolar Cycloaddition Reactions
1998 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Computer simulations of enzymatic reactions
1992 StandoutNobel
Mechanisms of Molecular Recognition : Investigations of Organic Host–Guest Complexes
1991
Asymmetric Dipolar Cycloaddition of Nitrile Oxides to the α,β-Unsaturated Esters Bearing an Imidazolidine Chiral Controller at the β-Position
1991
Diastereofacial selectivity in azomethine ylide cycloaddition reactions derived from chiral α-cyanoaminosilanes
1985
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Energetics of the Catalytic Reaction of Ribonuclease A: A Computational Study of Alternative Mechanisms
1998 StandoutNobel
ASYMMETRIC 1,3-DIPOLAR CYCLOADDITIONS FOR THE CONSTRUCTION OF ENANTIOMERICALLY PURE HETEROCYCLES. A REVIEW
2001
Enhanced Reactivity in Dioxirane C–H Oxidations via Strain Release: A Computational and Experimental Study
2013
Solute Solvent Dynamics and Energetics in Enzyme Catalysis: The SN2 Reaction of Dehalogenase as a General Benchmark
2004 StandoutNobel
Orbital Steering in the Catalytic Power of Enzymes: Small Structural Changes with Large Catalytic Consequences
1997 Science
Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation. 4. Electronic Effects in Amine-Accelerated Osmylations
1997 StandoutNobel
Evidence for a stepwise mechanism in formal hetero-Diels-Alder reactions of N-arylimines
1996
Stereoselective synthesis of 1,2-diols by the cycloadditive strategy: total synthesis of (±)-exo-brevicomin and (±)-and (–)-pestalotin
1991
Catalytic Asymmetric Hetero-Diels–Alder Reactions of Carbonyl Compounds and Imines
2000
An NMR Perspective on Enzyme Dynamics
2006
Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)–H Bonds: Scope and Mechanistic Studies
2015
Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method
2005 StandoutNobel
Asymmetric Induction in [3 + 2] Dipolar Cycloaddition Reactions of Nitrile Oxides with Chiral (α-Oxyallyl)silanes
1988
Cationic Iron(III) Porphyrin-Catalyzed [4 + 2] Cycloaddition of Unactivated Aldehydes with Simple Dienes
2012
Catalytic Asymmetric [4+2]-Cycloaddition of Dienes with Aldehydes
2017 StandoutNobel
Apparent NAC Effect in Chorismate Mutase Reflects Electrostatic Transition State Stabilization
2003 StandoutNobel
Unveiling the Delicate Balance of Steric and Dispersion Interactions in Organocatalysis Using High-Level Computational Methods
2020 StandoutNobel
Conformational Transmission of Chirality: The Origin of 1,4-Asymmetric Induction in Michael Reactions of Chiral Imines
1997
A molecular mechanics force field for NAD+ NADH, and the pyrophosphate groups of nucleotides
1997
Computer simulations of enzymatic reactions
1992 StandoutNobel
Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
1993
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
Cooperative Reactivity in an Extended-Viologen-Based Cyclophane
2016 StandoutNobel
Stereoselective Organic Reactions: Catalysts for Carbonyl Addition Processes
1988 Science
1,3-dipolar cycloaddition reactions of azomethine ylides on enantiomerically pure (E)-γ-alkoxy-α,β-unsaturated esters.
1991
Kinetic constraints on possible reaction pathways for osmium-catalysed asymmetric dihydroxylation
1996
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Catalytic Mechanism of Dihydrofolate Reductase Enzyme. A Combined Quantum-Mechanical/Molecular-Mechanical Characterization of Transition State Structure for the Hydride Transfer Step
1999
Aldolase Antibodies of Remarkable Scope
1998 StandoutNobel
Toward reliable density functional methods without adjustable parameters: The PBE0 model
1999 Standout
Generation of nitrile oxides through O-metalation of hydroximoyl chlorides. Chelation-controlled syn-selective cycloaddition of nitrile oxides to α-substituted allyl alcohols
1991
Homogeneous Catalysis in Supercritical Fluids
1999 StandoutNobel
Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
1996 StandoutScience
The Exterior Frontier Orbital Extension Model
1999
How Much Do Enzymes Really Gain by Restraining Their Reacting Fragments?
2002 StandoutNobel
Simulations of the Large Kinetic Isotope Effect and the Temperature Dependence of the Hydrogen Atom Transfer in Lipoxygenase
2004 StandoutNobel
Diastereoselective nitrile oxide cycloadditions to chiral allyl ethers derived from 1,1-dithio-3-buten-2-ols
1988
Diastereofacial Selectivity in the Cycloaddition of Nitrones to (E)-γ-Oxygenated α,β-Unsaturated Esters
1996
How Important Are Quantum Mechanical Nuclear Motions in Enzyme Catalysis?
1996 StandoutNobel
Fluorous Synthesis: A Fluorous-Phase Strategy for Improving Separation Efficiency in Organic Synthesis
1997 Science
Reaction-Path Energetics and Kinetics of the Hydride Transfer Reaction Catalyzed by Dihydrofolate Reductase
2003
Stereocontrolled Synthesis of Highly Substituted Proline Esters via [3 + 2] Cycloaddition between N-Metalated Azomethine Ylides and Nitroalkenes. Origins of the Metal Effect on the Stereochemical Outcome
1998
Asymmetric hetero-Diels–Alder reaction catalyzed by dirhodium(II) carboxamidates
2004
Asymmetric thermal reactions with oppolzer's camphor sultam
1993
Stereoselective intramolecular nitrone cycloadditions to chiral allyl ethers
1987
Highly enantioselective dihydroxylation of olefins by osmium tetroxide with chiral diamines
1993
Intramolecular Allylsilane Addition to Chiral Alkylidene‐1,3‐dicarbonyl Compounds for the Synthesis of Enantiomerically Pure trans‐1,2‐Disubstituted Cyclopentanes and Cyclohexanes
1995
Electrostatic effects in 1,3-dipolar cycloaddition reactions to chiral allyl ethers: a rationale for the experimentally observed diastereoselectivities
1993
Origin of π-facial stereoselectivity of hydride reduction of cyclohexanones. A new interpretation based on quantitative analysis of exterior frontier orbital extension
1997
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Modular Asymmetric Synthesis of 1,2-Diols by Single-Pot Allene Diboration/Hydroboration/Cross-Coupling
2006
Lewis Acid Coordinated Nitrile Oxide and Nitrile Imine 1,3-Dipoles. syn-Selective Cycloadditions to 2-(1-Hydroxyalkyl)acrylates
1993
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Hoch enantioselektive Hydrierung einfacher Ketone mit PennPhos-Rh-Katalysatoren
1998
Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents
2008 StandoutNobel
Hydride Transfer in Liver Alcohol Dehydrogenase: Quantum Dynamics, Kinetic Isotope Effects, and Role of Enzyme Motion
2001
Intramolecular nitrile oxide cycloaddition on chiral olefins: a stereocontrolled approach to β-ketol precursors
1987
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
IDPi Catalysis
2019 StandoutNobel
Recent advances in enantioselective copper-catalyzed 1,4-addition
2009 StandoutNobel
Construction of Enantiopure Pyrrolidine Ring System via Asymmetric [3+2]-Cycloaddition of Azomethine Ylides
2006 Standout
Quantitative Analysis of the Chiral Amplification in the Amino Alcohol-Promoted Asymmetric Alkylation of Aldehydes with Dialkylzincs
1998 StandoutNobel
Diastereofacial selectivity in intermolecular nitrone cycloadditions to chiral allyl ethers. Application to Chiral Synthesis of Coniine
1992
Cycloaddition of nitrile oxides to homochiral vinyl ethers
1994
Intramolekulare Allylsilan‐Addition an chirale Alkyliden‐1,3‐dicarbonylverbindungen zur Synthese enantiomerenreiner trans‐1,2‐disubstituierter Cyclopentane und Cyclohexane
1995
Catalytic Functionalization of Arenes and Alkanes via C−H Bond Activation
2001
Computer Simulation Studies of the Catalytic Mechanism of Human Aldose Reductase
2000 StandoutNobel
The diastereoselectivity of intermolecular nitrone cycloaddition to chiral allyl derivatives
1991
Diels–Alder reactions: An assessment of quantum chemical procedures
1997
Asymmetric 1,3-dipolar cycloadditions to 5-menthyloxy-2[5H]-furanones.
1988 StandoutNobel
Simulation of enzyme reactions using valence bond force fields and other hybrid quantum/classical approaches
1993 StandoutNobel
Synthesis of enantiomerically pure pyrrolidines by stereospecific cycloaddition of azomethine ylides with enones
1993
Chiral Metal Complexes as Discriminating Molecular Catalysts
1990 StandoutScienceNobel
Theory and Modeling of Stereoselective Organic Reactions
1986 Science
Total synthesis of (+)-monomorine I via nitrone cycloaddition route
1991
Prolin‐benzylester als chirale Hilfsgruppen in asymmetrischen 1,3‐dipolaren Cycloadditionen mit Nitriloxiden
1990
The Carbon−Lithium Electron Pair Bond in (CH3Li)n(n= 1, 2, 4)
1996
A combined ab initio quantum mechanical and molecular mechanical method for carrying out simulations on complex molecular systems: Applications to the CH3Cl + Cl− exchange reaction and gas phase protonation of polyethers
1986
Katalytische asymmetrische Hetero-Diels-Alder-Reaktionen von Carbonylverbindungen und Iminen
2000
Enantioselektive Addition von Organometallreagentien an Carbonylverbindungen: Übertragung, Vervielfältigung und Verstärkung der Chiralität
1991 StandoutNobel
Hybrid Models for Combined Quantum Mechanical and Molecular Mechanical Approaches
1996
Z-Selective Copper-Catalyzed Asymmetric Allylic Alkylation with Grignard Reagents
2012 StandoutNobel
Efficient and versatile synthesis of mucin-like glycoprotein mimics
2002
Wherefore Art Thou Copper? Structures and Reaction Mechanisms of Organocuprate Clusters in Organic Chemistry
2000
Organische Synthese — wohin?
1990
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Structure, Dynamics, and Catalytic Function of Dihydrofolate Reductase
2004
Enantioselective Addition of Organometallic Reagents to Carbonyl Compounds: Chirality Transfer, Multiplication, and Amplification
1991 StandoutNobel
Relevance of Weak Hydrogen Bonds in the Conformation of Organic Compounds and Bioconjugates: Evidence from Recent Experimental Data and High-Levelab InitioMO Calculations
2010
An alternative enantioselective total synthesis of (+)-monomorine I
1990
Highly enantioselective hetero-Diels–Alder reaction between trans-1-methoxy-2-methyl-3-trimethylsiloxybuta-1,3-diene and aldehydes catalyzed by (R)-BINOL–Ti(IV) complex
2005
Diastereoselectivity in the SE2? reaction of chiral pentadienylsilanes: a test for the relative importance of steric and electronic effects
1996
Nitrone cycloadditions to 2,3-dihydro-1-phenyl-1H-phosphole 1-oxide. Double asymmetric induction and kinetic resolution by a chiral nitrone
1991
The reaction of lithium with hydrogen. a model ab initio study
1986 StandoutNobel
Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima
2003
Works of Yun Wu being referenced
Pd-Catalyzed C(sp3)–H Carbonylation of Alkylamines: A Powerful Route to γ-Lactams and γ-Amino Acids
2015
Stereoselective nitrile oxide cycloadditions to chiral allyl ethers and alcohols. The inside alkoxy effect
1984
Palladium‐Catalyzed CF Bond Formation via Directed CH Activation
2014
exo-Lone-pair effect on hetero-Diels-Alder cycloaddition stereochemistry
1992
Ab initio mechanisms for the addition of methyllithium, lithium hydride, and their dimers to formaldehyde
1985
Transition structures for hydride transfers
1987
Hetero-Diels-Alder reaction transition structures: reactivity, stereoselectivity, catalysis, solvent effects, and the exo-lone-pair effect
1993
Conformational preferences of the O-C-C-C unit in acyclic and cyclic systems. The exo-deoxoanomeric effect and related phenomena
1993
Stereoselectivities of nucleophilic additions to cyclohexanones substituted by polar groups. Experimental investigation of reductions of trans-decalones and theoretical studies of cyclohexanone reductions. The influence of remote electrostatic effects
1991
Conformations of cycloheptadecane. A comparison of methods for conformational searching
1990
Electrostatic control of the stereochemistry of nucleophilic additions to substituted 7-norbornanones
1992
Ab initio transition structures for hydroborations of alkenes, allenes, and alkynes by borane, diborane, methylborane, methylfluoroborane, and dimethylborane
1990
Experimental tests of models to predict nucleophilic addition stereochemistries
1988
Steric models for stereoselectivity of nitrile oxide cycloadditions to chiral alkenes
1986
Electronic and conformational effects on .pi.-facial stereoselectivity in nucleophilic additions to carbonyl compounds
1987
Origin of enhanced axial attack by sterically undemanding nucleophiles on cyclohexenones
1987
Theoretical transition structures for hydride transfer to methyleneiminium ion from methylamine and dihydropyridine. On the nonlinearity of hydride transfers
1987
Theoretical study of conformational features of NAD+ and NADH analogs: protonated nicotinamide and 1,4-dihydronicotinamide
1993
Organoboron compounds in organic synthesis. 3. Mechanism of asymmetric reduction of dialkyl ketones with (R,R)-2,5-dimethylborolane
1986
Theoretical evaluation of conformational preferences of NAD+ and NADH: an approach to understanding the stereospecificity of NAD+/NADH-dependent dehydrogenases
1991
Mechanism of the Ziegler dilithiomethane synthesis. An ab initio study of methyllithium pyrolysis
1992
A new model for the stereoselectivities of dihydroxylations of alkenes by chiral diamine complexes of osmium tetroxide
1992