Citation Impact
Citing Papers
Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase–Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer
2009
Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses
2007
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
2008
The Indoleamine-2,3-Dioxygenase (IDO) Inhibitor 1-Methyl-D-tryptophan Upregulates IDO1 in Human Cancer Cells
2011
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation
2012
Asymmetric Catalysis on the Nanoscale: The Organocatalytic Approach to Helicenes
2014 StandoutNobel
A view on drug resistance in cancer
2019 StandoutNature
Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model
2006
Catalytic Asymmetric Benzidine Rearrangement
2013 StandoutNobel
Ovarian cancer biomarkers for molecular biosensors and translational medicine
2010
Lorlatinib in non-small-cell lung cancer with ALK or ROS1 rearrangement: an international, multicentre, open-label, single-arm first-in-man phase 1 trial
2017
A guide to immunometabolism for immunologists
2016 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
2014 Standout
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics
2010 StandoutNobel
Host Indoleamine 2,3-Dioxygenase: Contribution to Systemic Acquired Tumor Tolerance
2012
Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
2006
Indoleamine 2,3‐dioxygenase in T‐cell tolerance and tumoral immune escape
2008
Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial
2015
Modulation of host metabolism as a target of new antivirals
2007
Direct Oxidative Heck Cyclizations: Intramolecular Fujiwara–Moritani Arylations for the Synthesis of Functionalized Benzofurans and Dihydrobenzofurans
2004
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Suppression of virus replication via down-modulation of mitochondrial short chain enoyl-CoA hydratase in human glioblastoma cells
2007
Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment
2014
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Anaplastic lymphoma kinase as a therapeutic target
2012
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Indoleamine 2,3-dioxygenase and tumor-induced tolerance
2007
Improved Cyclopropanation Activity of Histidine‐Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran
2014 StandoutNobel
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
Production of lipospheres as carriers for bioactive compounds
2002
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Replication of hepatitis C virus
2007 StandoutNobel
Catalytic Asymmetric Organozinc Additions to Carbonyl Compounds
2001
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Phosphoinositides in the Hepatitis C Virus Life Cycle
2012
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
O-Glycosylation
2001
Exploring new reactive species for cyclopropanation
1998
Photoinduced alkyl group exchange of ethylzinc alkoxides: X-ray crystal structure of an iodomethylzinc methoxide
2002
Hallmarks of Hepatitis C Virus in Equine Hepacivirus
2014
Symmetry Breaking in Asymmetric Catalysis: Racemic Catalysis to Autocatalysis
2003
Catalytic Asymmetric Cyclopropanation of Allylic Alcohols with Titanium-TADDOLate: Scope of the Cyclopropanation Reaction
2001
BINOL: A Versatile Chiral Reagent
2005 Standout
Place navigation impaired in rats with hippocampal lesions
1982 StandoutNatureNobel
Enantioselective Synthesis of 1,2,3-Trisubstituted Cyclopropanes Using gem-Dizinc Reagents
2009
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Targeting ALK: Precision Medicine Takes on Drug Resistance
2017
Remarkable Tumor Response to Crizotinib in a 14-Year-Old Girl With ALK-Positive Non–Small-Cell Lung Cancer
2012
Targeted metabolic labeling of yeast N-glycans with unnatural sugars
2010 StandoutNobel
Functionalized Major-Groove and Minor-Groove Chiral Polybinaphthyls: Application in the Asymmetric Reaction of Aldehydes with Diethylzinc
1997
Monodisperse Double Emulsions Generated from a Microcapillary Device
2005 StandoutScience
Enantioselective Oxidative Biaryl Coupling Reactions Catalyzed by 1,5-Diazadecalin Metal Complexes: Efficient Formation of Chiral Functionalized BINOL Derivatives
2003
The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
2015
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Stereoselective Cyclopropanation Reactions
2003 Standout
A Highly General Catalyst for the Enantioselective Reaction of Aldehydes with Diethylzinc
1998
Helicenes: Synthesis and Applications
2011 Standout
Emerging host cell targets for hepatitis C therapy
2007
Asymmetric Allylboration of Aldehydes and Ketones Using 3,3‘-Disubstitutedbinaphthol-Modified Boronates
2004
Azine Activation via Silylium Catalysis
2021 StandoutNobel
New Targets and Screening Approaches in Antimicrobial Drug Discovery
2005
Poly(1,1‘-bi-2-naphthol)s: Synthesis, Characterization, and Application in Lewis Acid Catalysis
1996
Inhibitors of the anaplastic lymphoma kinase
2012
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
2018 StandoutScienceNobel
Chiral Synthesis of Cyclopropanes. Stereoselective [2 + 1] Cycloaddition Reactions of 1-Seleno-2-silylethenes with Di-(−)-menthyl Ethene-1,1-dicarboxylates
1999
Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.
2006
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Recent advances in enantioselective copper-catalyzed 1,4-addition
2009 StandoutNobel
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
Ambifunctional cooperative catalysts
2001
New Family of Cyclopropanating Reagents: Synthesis, Reactivity, and Stability Studies of Iodomethylzinc Phenoxides This work was supported by the E.W.R. Steacie Fund, the National Science and Engineering Research Council (NSERC) of Canada, Merck Frosst Canada, Boehringer Ingelheim (Canada), F.C.A.R. (Québec), and the Université de Montréal. J.M. and S.F. are grateful to NSERC and F.C.A.R. respectively for postgraduate fellowships.
2000
Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators
2011
The Neuropsychology of Anxiety
2003 Standout
Increased synthesis of indoleamine-2,3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer
2007
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection
2008
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Synthesis, Structural Analysis, and Catalytic Properties of Tetrakis(binaphthyl or octahydrobinaphthyl phosphate) Dirhodium(II,II) Complexes
2013
Jietacins with potent nematocidal activity; efficient isolation of novel analogs and divergent total synthesis of jietacin A, B, C, and D
2015 StandoutNobel
Modified BINOL Ligands in Asymmetric Catalysis
2003
Asymmetrische Aktivierung
2000
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
2013 StandoutNobel
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Asymmetric Activation
2000
New Family of Cyclopropanating Reagents: Synthesis, Reactivity, and Stability Studies of Iodomethylzinc Phenoxides
2000
1,1‘-Binaphthyl Dimers, Oligomers, and Polymers: Molecular Recognition, Asymmetric Catalysis, and New Materials
1998 Standout
Works of Yuko Aoki being referenced
Functional Characterization of the Candida albicans MNT1Mannosyltransferase Expressed Heterologously in Pichia pastoris
2000
A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes
2013
CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant
2011
Panic attacks and panic disorder in a Japanese non-patient population: epidemiology and psychosocial correlates
1994
Azoxybacilin, a novel antifungal agent produced by Bacillus cereus NR2991. Production, isolation and structure elucidation.
1994
Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase
2003
Host sphingolipid biosynthesis as a target for hepatitis C virus therapy
2005
N,N,N′,N′-Tetraalkyl-2,2′-dihydroxy-1,1′-binaphthyl-3,3′-dicarboxamides: Novel Chiral Auxiliaries for Asymmetric Simmons–Smith Cyclopropanation of Allylic Alcohols and for Asymmetric Diethylzinc Addition to Aldehydes
1997
Indoleamine 2,3-Dioxygenase Serves as a Marker of Poor Prognosis in Gene Expression Profiles of Serous Ovarian Cancer Cells
2005
Ex vivo anti-platelet effects of isocarbacyclin methyl ester incorporated in lipid microspheres in rabbits.
1995
Asymmetric Simmons-Smith Cyclopropanation of E-Allylic Alcohols Using 1,1′-Bi-2-naphthol-3,3′-dicarboxamide as a Chiral Auxiliary
1995
Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties
2013