Standout Papers
Citation Impact
Citing Papers
The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25
2006 StandoutNobel
MicroRNA Gene Expression Deregulation in Human Breast Cancer
2005 Standout
Sequence Variations of MicroRNAs in Human Cancer: Alterations in Predicted Secondary Structure Do Not Affect Processing
2006
The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells
2007
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease
2002 StandoutScienceNobel
A microRNA expression signature of human solid tumors defines cancer gene targets
2006 Standout
miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
A Polycistronic MicroRNA Cluster, miR-17-92 , Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation
2005
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Isothermal amplified detection of DNA and RNA
2014
Hallmarks of Cancer: The Next Generation
2011 Standout
Meta-analysis of randomised adjuvant therapy trials for pancreatic cancer
2005
Regulation of microRNA function in animals
2018 Standout
The Rel/NF-κB family: friend and foe
2000
IKKε and TBK1 are essential components of the IRF3 signaling pathway
2003 Standout
A Drosophila IκB kinase complex required for Relish cleavage and antibacterial immunity
2000
Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages
2010
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
The IKK complex: an integrator of all signals that activate NF-κB?
2000
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?
2005
Adjuvant Chemotherapy With Gemcitabine and Long-term Outcomes Among Patients With Resected Pancreatic Cancer
2013
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
A Randomized Trial of Chemoradiotherapy and Chemotherapy after Resection of Pancreatic Cancer
2004 Standout
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
2007
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription
2000
Classification of Surgical Complications
2004 Standout
Pancreatic cancer
2016 Standout
Microarray-based, high-throughput gene expression profiling of microRNAs
2004
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
Role of Drosophila IKKγ in a Toll-independent antibacterial immune response
2000 StandoutNobel
MicroRNAs as oncogenes
2005
Bcl10 and MALT1, Independent Targets of Chromosomal Translocation in MALT Lymphoma, Cooperate in a Novel NF-κB Signaling Pathway
2001
A Multicenter Randomized Controlled Trial to Evaluate the Effect of Adjuvant Cisplatin and 5-Fluorouracil Therapy after Curative Resection in Cases of Pancreatic Cancer
2006
Missing Pieces in the NF-κB Puzzle
2002 Standout
The Phosphorylation Status of Nuclear NF-ΚB Determines Its Association with CBP/p300 or HDAC-1
2002
A Prospective Randomized Controlled Study Comparing Outcomes of Standard Resection and Extended Resection, Including Dissection of the Nerve Plexus and Various Lymph Nodes, in Patients With Pancreatic Head Cancer
2013
Real-time expression profiling of microRNA precursors in human cancer cell lines
2005
Reduced expression of Dicer associated with poor prognosis in lung cancer patients
2005
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
2005
Uniaxial Cyclic Stretch Induces Focal Adhesion Kinase (FAK) Tyrosine Phosphorylation Followed by Mitogen-Activated Protein Kinase (MAPK) Activation
2001
Protein kinase C-θ: signaling from the center of the T-cell synapse
2002
The immune response of Drosophila
2003 StandoutNatureNobel
Oncomirs — microRNAs with a role in cancer
2006 Standout
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
2006
IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2
2002
Toll receptors in innate immunity
2001 StandoutNobel
Complete Reconstitution of Human IκB Kinase (IKK) Complex in Yeast
2001
MicroRNAs in cell proliferation, cell death, and tumorigenesis
2006
NF-κB regulation in the immune system
2002 Standout
Adjuvant Chemotherapy With Gemcitabine vs Observation in Patients Undergoing Curative-Intent Resection of Pancreatic Cancer
2007 Standout
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
2008 Standout
Quality of Complication Reporting in the Surgical Literature
2002
Ageing and telomeres: a study into organ- and gender-specific telomere shortening
2003
MicroRNA signatures in human cancers
2006 Standout
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
2006
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
BIC and miR‐155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas
2005
Small regulatory RNAs in mammals
2005
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Bimp1, a MAGUK Family Member Linking Protein Kinase C Activation to Bcl10-mediated NF-κB Induction
2001
NF-κB: a key role in inflammatory diseases
2001 Standout
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
2006 Standout
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
The essential role of MEKK3 in TNF-induced NF-κB activation
2001
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
Camels and zebrafish, viruses and cancer: a microRNA update
2005
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
MicroRNAs in vertebrate development
2005
A new family of IKK-related kinases may function as IκB kinase kinases
2001
Extensive modulation of a set of microRNAs in primary glioblastoma
2005
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Toll-Like Receptors
2003 Standout
The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection
2004
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
MicroRNA Biogenesis and Cancer
2005
Inhibition of RIG-I-Dependent Signaling to the Interferon Pathway during Hepatitis C Virus Expression and Restoration of Signaling by IKKε
2005
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
microRNAs exhibit high frequency genomic alterations in human cancer
2006
Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes
2002
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
Uni‐axial cyclic stretch induces the activation of transcription factor nuclear factor κB in human fibroblast cells
2002
A genome-wide analysis of immune responses in Drosophila
2001 StandoutNobel
The role of microRNA genes in papillary thyroid carcinoma
2005 Standout
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Adjuvant Treatment for Resectable Pancreatic Cancer
2005
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
Let-7 expression defines two differentiation stages of cancer
2007
The Temporal Patterning MicroRNA let-7 Regulates Several Transcription Factors at the Larval to Adult Transition in C. elegans
2005
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors
2003 StandoutScienceNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior
2006
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
2004
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Triggering the Interferon Antiviral Response Through an IKK-Related Pathway
2003 Science
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
2005
let-7 MicroRNA Functions as a Potential Growth Suppressor in Human Colon Cancer Cells
2006
MicroRNA-Cancer Connection: The Beginning of a New Tale
2006
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation
2007 Science
Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding
2013
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Works of Yuji Nimura being referenced
Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival
2004 Standout
The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function
2001
Change in Telomerase Activity of Rat Organs during Growth and Aging
1998
Identification and Characterization of Human DNA Polymerase β2, a DNA Polymerase β-Related Enzyme
2000
Up-regulation of Integrin β3Expression by Cyclic Stretch in Human Umbilical Endothelial Cells
1997
SA channel mediates superoxide production in HUVECs
2001
Synergistic effect of interleukin-15 and interleukin-12 on antitumor activity in a murine malignant pleurisy model
2000
Effect of chitosan film containing basic fibroblast growth factor on wound healing in genetically diabetic mice
2002
Is postoperative adjuvant chemotherapy useful for gallbladder carcinoma?
2002
NAK is an IκB kinase-activating kinase
2000 Nature
Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas
2011
Complications of Hepatectomy for Hilar Cholangiocarcinoma
2001
Expression of Toll-Like Receptor 2 on γδ T Cells Bearing Invariant Vγ6/Vδ1 Induced by Escherichia coli Infection in Mice
2000