Citation Impact
Citing Papers
The transcription factor Slug repressesE-cadherinexpression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
2002
Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells
2009
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription
2005
Genetic Profiling of Epithelial Cells Expressing E-Cadherin Repressors Reveals a Distinct Role for Snail, Slug, and E47 Factors in Epithelial-Mesenchymal Transition
2006
Snail and Slug Play Distinct Roles during Breast Carcinoma Progression
2006
Cell delamination in the mesencephalic neural fold and its implication for the origin of ectomesenchyme
2013
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron
2007
Snail is an immediate early target gene of parathyroid hormone related peptide signaling in parietal endoderm formation
2000
Snail regulates p21WAF/CIP1 expression in cooperation with E2A and Twist
2004
Mesenchyme Forkhead 1 ( FOXC2 ) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
2007
The transcriptional repressor Snail promotes mammary tumor recurrence
2005
Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression
2010
Hallmarks of Cancer: The Next Generation
2011 Standout
Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
2000
Transforming Growth Factor β-1 Induces Snail Transcription Factor in Epithelial Cell Lines
2003
Mouse Snail Is a Target Gene for HIF
2011
Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation
2011
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Mammalian Merkel cells are descended from the epidermal lineage
2009
Mesp1 Coordinately Regulates Cardiovascular Fate Restriction and Epithelial-Mesenchymal Transition in Differentiating ESCs
2008
Smad3 Signaling Is Required for Epithelial-Mesenchymal Transition of Lens Epithelium after Injury
2004
Inhibition of Neural Crest Migration in Xenopus Using Antisense Slug RNA
1999
Spotlight on Spotted Mice: A Review of White Spotting Mouse Mutants and Associated Human Pigmentation Disorders
2004
T‐box genes in early embryogenesis
2003
Notch signaling and inherited disease syndromes
2003
Unraveling signalling cascades for the Snail family of transcription factors
2004
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
2003
Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo
2002
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
Notch/RBP-J Signaling Regulates Epidermis/Hair Fate Determination of Hair Follicular Stem Cells
2003 StandoutNobel
Target Selectivity of Vertebrate Notch Proteins
2005
A Signaling Pathway Involving TGF-β2 and Snail in Hair Follicle Morphogenesis
2004
Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion
2009
Expression of Snail protein in tumor–stroma interface
2006
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo
2006
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines
2008
Peritoneal Dialysis and Epithelial-to-Mesenchymal Transition of Mesothelial Cells
2003
Back and forth between cell fate specification and movement during vertebrate gastrulation
2008
Multiple roles of Notch signaling in cochlear development
2007 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma
2004
Cell-cycle checkpoints and cancer
2004 StandoutNature
Mouse Models for Four Types of Waardenburg Syndrome
2003
Notch activity acts as a sensor for extracellular calcium during vertebrate left–right determination
2004 Nature
Differential Expression of the Epithelial-Mesenchymal Transition Regulators Snail, SIP1, and Twist in Gastric Cancer
2002
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
2008 Standout
Cutaneous wound reepithelialization is compromised in mice lacking functional Slug (Snai2)
2009
Limb development: a paradigm of gene regulation
2017
Biological Potential of a Functional Human SNAILRetrogene
2002
Snail1 transcriptional repressor binds to its own promoter and controls its expression
2006
Cell movements during gastrulation: Snail dependent and independent pathways
2002
Regulation of E-cadherin expression and β-catenin/Tcf transcriptional activity by the integrin-linked kinase
2003
The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
2000 Standout
A Wnt–Axin2–GSK3β cascade regulates Snail1 activity in breast cancer cells
2006
Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases
2009
Overexpression of Snail family members highlights their ability to promote chick neural crest formation
2002
Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells
2004
Sinistral Snails and Gentlemen Scientists
2005 StandoutNobel
SLUG, a ces-1-Related Zinc Finger Transcription Factor Gene with Antiapoptotic Activity, Is a Downstream Target of the E2A-HLF Oncoprotein
1999
Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse
2005
A crucial function of PDGF in TGF-β-mediated cancer progression of hepatocytes
2006
MTHFRandMSX1contribute to the risk of nonsyndromic cleft lip/palate
2010
Regulation of Marginal Zone B Cell Development by MINT, a Suppressor of Notch/RBP-J Signaling Pathway
2003 StandoutNobel
Complex networks orchestrate epithelial–mesenchymal transitions
2006 Standout
Small C-terminal Domain Phosphatase Enhances Snail Activity through Dephosphorylation
2008
Ets2-dependent trophoblast signalling is required for gastrulation progression after primitive streak initiation
2013
A Single-Cell Transcriptome Atlas of the Human Pancreas
2016
TGF-β and epithelial-to-mesenchymal transitions
2005
Medical Sequencing of Candidate Genes for Nonsyndromic Cleft Lip and Palate
2005
The Transcriptional Control of Trunk Neural Crest Induction, Survival, and Delamination
2005
Left–right asymmetry in embryonic development: a comprehensive review
2004
Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly Brain
2003 StandoutNobel
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Sticky Business
2003
Cleft lip and palate: understanding genetic and environmental influences
2011 Standout
Hepatocyte growth factor induces cell scattering through MAPK/Egr‐1‐mediated upregulation of Snail
2006
Epithelial–mesenchymal transitions in tumour progression
2002 Standout
Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence
2009
Cleft lip and palate
2009 Standout
Snail-Related Transcriptional Repressors Are Required in Xenopus for both the Induction of the Neural Crest and Its Subsequent Migration
2000
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Expression of the Transcription Factors Snail, Slug, and Twist and Their Clinical Significance in Human Breast Cancer
2005
The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug
2003
Epiblast-specific Snai1 deletion results in embryonic lethality due to multiple vascular defects
2009
Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3
2008
Immunity, Inflammation, and Cancer
2010 Standout
The genetics of isolated orofacial clefts: from genotypes to subphenotypes
2009
The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality
2013 Nature
Molecular control of secondary palate development
2006
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
Building strong bones: molecular regulation of the osteoblast lineage
2011
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Ajuba LIM Proteins Are Snail/Slug Corepressors Required for Neural Crest Development in Xenopus
2008
EMT: 2016
2016 Standout
Functional redundancy of the Notch gene family during mouse embryogenesis: Analysis of Notch gene expression in Notch3-deficient mice
2005
A Chemosensory Gene Family Encoding Candidate Gustatory and Olfactory Receptors in Drosophila
2001 StandoutNobel
The early steps of neural crest development
2001
Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells
2005
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems
2000
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Bare rudiments of notch signaling: how receptor levels are regulated
2007
Tbx22 null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes
2009
Spatial Representation of the Glomerular Map in the Drosophila Protocerebrum
2002 StandoutNobel
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial–mesenchymal transition of lens epithelium in mice
2004
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
2003
Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis
2004 Standout
Polycomb complexes repress developmental regulators in murine embryonic stem cells
2006 StandoutNature
Leaving the neighborhood: molecular mechanisms involved during epithelial‐mesenchymal transition
2001
Transient Overexpression of TGF-β1 Induces Epithelial Mesenchymal Transition in the Rodent Peritoneum
2004
Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test
2006
Development of the upper lip: Morphogenetic and molecular mechanisms
2005
A Novel Gene Product that Couples TCR Signaling to Fas(CD95) Expression in Activation-Induced Cell Death
1996
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
2001
E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations
2005
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation
2011
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
2002
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Mouse cDNA microarray analysis uncovers Slug targets in mouse embryonic fibroblasts
2005
Cell movements during vertebrate development: integrated tissue behaviour versus individual cell migration
2001
Snail controls differentiation of hepatocytes by repressing HNF4α expression
2006
Comprehensive Integration of Single-Cell Data
2019 Standout
The snail superfamily of zinc-finger transcription factors
2002
Developmental transcription factor slug is required for effective re‐epithelialization by adult keratinocytes
2004
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Crystal structure of a paired domain-DNA complex at 2.5 å resolution reveals structural basis for pax developmental mutations
1995
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Snail/Slug family of repressors: slowly going into the fast lane of development and cancer
2000
Oscillations of the Snail Genes in the Presomitic Mesoderm Coordinate Segmental Patterning and Morphogenesis in Vertebrate Somitogenesis
2006
Gene-Regulatory Interactions in Neural Crest Evolution and Development
2004
Genetic Determinants of Facial Clefting: Analysis of 357 Candidate Genes Using Two National Cleft Studies from Scandinavia
2009
Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression andZEB1 Expression
2002
p38 and a p38-Interacting Protein Are Critical for Downregulation of E-Cadherin during Mouse Gastrulation
2006
Epigenetic Regulation of EMT: The Snail Story
2014
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
2004 StandoutNobel
Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling
2008
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Snail genes at the crossroads of symmetric and asymmetric processes in the developing mesoderm
2006
Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm.
1994
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway
2002
TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops
2014
Epithelial-mesenchymal transitions: insights from development
2012
Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion
2009
The Snail genes as inducers of cell movement and survival: implications in development and cancer
2005
Neonatal Lethality of LGR5 Null Mice Is Associated with Ankyloglossia and Gastrointestinal Distension
2004
Vascular Endothelial Growth Factor Expression in Peritoneal Mesothelial Cells Undergoing Transdifferentiation
2008
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes
2010
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial–mesenchymal transition
2008
Aberrant Expression of the Transcription Factors Snail and Slug Alters the Response to Genotoxic Stress
2004
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Snail blocks the cell cycle and confers resistance to cell death
2004
Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
2006 StandoutNobel
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
2003
Pivotal roles for eomesodermin during axis formation,epithelium-to-mesenchyme transition and endoderm specification in the mouse
2008
Snail2 directly represses cadherin6B during epithelial-to-mesenchymal transitions of the neural crest
2007
Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor
2008
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Phosphorylation Regulates the Subcellular Location and Activity of the Snail Transcriptional Repressor
2003
Snail family genes are required for left–right asymmetry determination, but not neural crest formation, in mice
2006
Neural Science
2000 StandoutNobel
The Notch ligand Jagged1 is required for inner ear sensory development
2001
Regulation of Slug transcription in embryonic ectoderm by β‐catenin‐Lef/Tcf and BMP‐Smad signaling
2005
Generation of hair cells by stepwise differentiation of embryonic stem cells
2003
Erk5 Controls Slug Expression and Keratinocyte Activation during Wound Healing
2008
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.
1995
The protein tyrosine phosphatase Pez regulates TGFβ, epithelial–mesenchymal transition, and organ development
2007
Snail family members and cell survival in physiological and pathological cleft palates
2003
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Distinct functions for Bmp signaling in lip and palate fusion in mice
2005
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.
2002
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
2008
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
2010
Conservation of neurogenic genes and mechanisms
1999
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex
2003
Human Slug Is a Repressor That Localizes to Sites of Active Transcription
2000
Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis
2008
The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo
2007
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Snail and E47 repressors ofE-cadherininduce distinct invasive and angiogenic properties in vivo
2004
Molecular Mechanisms of Epithelial Morphogenesis
2002
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Establishing neural crest identity: a gene regulatory recipe
2015
Transcription RepressorSlugPromotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma
2005
Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa
2006
Endocardial Notch Signaling in Cardiac Development and Disease
2015
Works of Yu Lan being referenced
Whole transcriptome expression profiling of mouse limb tendon development by using RNA‐seq
2015
Hand2 is required in the epithelium for palatogenesis in mice
2009
Jag2‐Notch1 signaling regulates oral epithelial differentiation and palate development
2006
Isolation and developmental expression analysis of Tbx22, the mouse homolog of the human X‐linked cleft palate gene
2002
Identification and developmental expression analysis of a novel homeobox gene closely linked to the mouse Twirler mutation
2006
Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation
2010
Notch signaling regulates left–right asymmetry determination by inducingNodalexpression
2003
Notch signalling pathway mediates hair cell development in mammalian cochlea
1999
Expression of Wnt9b and activation of canonical Wnt signaling during midfacial morphogenesis in mice
2006
Dissection of the Drosophila paired protein: Functional requirements for conserved motifs
1994
The cleft lip and palate defects inDancermutant mice result from gain of function of theTbx10gene
2004
Synergistic activation of transcription is mediated by the N-terminal domain of Drosophila fushi tarazu homeoprotein and can occur without DNA binding by the protein.
1993
The slug gene is not essential for mesoderm or neural crest development in mice
1998
Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis
2014
Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation
2001
Odd-skipped related-1 controls neural crest chondrogenesis during tongue development
2013
The Mn1 transcription factor acts upstream ofTbx22and preferentially regulates posterior palate growth in mice
2008
Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis
2004
Smad4 is required for maintaining normal murine postnatal bone homeostasis
2007
The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition
2001