Citation Impact
Citing Papers
Genetically Encoding Fluorosulfate- l -tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo
2018
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Autophagy Is Activated by TGF-β and Potentiates TGF-β–Mediated Growth Inhibition in Human Hepatocellular Carcinoma Cells
2009
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Treg Therapy for the Induction of Immune Tolerance in Transplantation—Not Lost in Translation?
2023
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
2018 StandoutNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins
2019
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
The multifaceted regulation and functions of PKM2 in tumor progression
2014
Genomic and Epigenomic Aberrations in Esophageal Squamous Cell Carcinoma and Implications for Patients
2017
Opportunities for therapeutic antibodies directed at G-protein-coupled receptors
2017
A view on drug resistance in cancer
2019 StandoutNature
Mechanism and medical implications of mammalian autophagy
2018 Standout
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
The Principles of Engineering Immune Cells to Treat Cancer
2017
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs
2021 StandoutNobel
Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation
2015
Oxygen availability and metabolic adaptations
2016
Hepatocellular carcinoma
2021 Standout
CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity
2019 StandoutNobel
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
2016
Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
2018
Delivery technologies for cancer immunotherapy
2019 Standout
Engineered T cells: the promise and challenges of cancer immunotherapy
2016
Chimeric antigen receptors: driving immunology towards synthetic biology
2016
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Human antibody-based chemically induced dimerizers for cell therapeutic applications
2017
Expanding and reprogramming the genetic code
2017 Nature
Programmable synthetic receptors: the next-generation of cell and gene therapies
2024
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
T cells expressing chimeric antigen receptor promote immune tolerance
2017
Oxidative Stress in Cancer
2020 Standout
Engineered Cell-Based Therapeutics: Synthetic Biology Meets Immunology
2019
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Making CAR T Cells a Solid Option for Solid Tumors
2018
Emerging formats for next-generation antibody drug conjugates
2015
Engineering strategies to overcome the current roadblocks in CAR T cell therapy
2019
Defining trained immunity and its role in health and disease
2020 Standout
Maftools: efficient and comprehensive analysis of somatic variants in cancer
2018 Standout
Opportunities for Treg cell therapy for the treatment of human disease
2023 StandoutNobel
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Cell-penetrating peptides: classes, origin, and current landscape
2012
3d Transition Metals for C–H Activation
2018 Standout
Enzyme stabilization via computationally guided protein stapling
2017
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity
2022 StandoutNobel
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
2023 StandoutNobel
Playing with the Molecules of Life
2018
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Intracellular Delivery of a Proapoptotic Peptide via Conjugation to a RAFT Synthesized Endosomolytic Polymer
2009
Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization
2022
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Therapeutic Targeting of the Tumor Microenvironment
2021
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
2023 StandoutNobel
Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases
2019
Chimeric antigen receptor–modified T cells: CD19 and the road beyond
2018
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Chimeric Antigen Receptor Therapy
2018 Standout
Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine–Lysine Relay
2018 StandoutNobel
Using Singlet Oxygen to Synthesize Natural Products and Drugs
2016
Chemo- and Regioselective Lysine Modification on Native Proteins
2018
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors
2020
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Antibody–Enzyme Fusion Proteins for Cancer Therapy
2011
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis
2016
Precise T cell recognition programs designed by transcriptionally linking multiple receptors
2020 Science
Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids
2018
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins
2019
Postsynthetic Incorporation of a Singlet Oxygen Photosensitizer in a Metal–Organic Framework for Fast and Selective Oxidative Detoxification of Sulfur Mustard
2016 StandoutNobel
Proximity-enabled bioreactivity to generate covalent peptide inhibitors of p53–Mdm4
2016
Advances in Chemical Protein Modification
2015
Works of Yu Cao being referenced
Construction and Characterization of Novel, Recombinant Immunotoxins Targeting the Her2/neu Oncogene Product: In vitro and In vivo Studies
2009
Single-Chain Antibody-Based Immunotoxins Targeting Her2/neu: Design Optimization and Impact of Affinity on Antitumor Efficacy and Off-Target Toxicity
2011
A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes
2014
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer
2016
EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis
2012
Engineered T Cell Therapy for Cancer in the Clinic
2019
Aberrant overexpression of EZH2 and H3K27me3 serves as poor prognostic biomarker for esophageal squamous cell carcinoma patients
2015
Oral Administration of Nano-Emulsion Curcumin in Mice Suppresses Inflammatory-Induced NFκB Signaling and Macrophage Migration
2014
Biomimetic Synthesis: Discovery of Xanthanolide Dimers
2014
An Immunosuppressive Antibody–Drug Conjugate
2015
A Short Nur77-Derived Peptide Converts Bcl-2 from a Protector to a Killer
2008
Redirection of Genetically Engineered CAR-T Cells Using Bifunctional Small Molecules
2015
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies
2016
Versatile strategy for controlling the specificity and activity of engineered T cells
2016