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Citing Papers
Synergistic and tunable human gene activation by combinations of synthetic transcription factors
2013
Direct and continuous assessment by cells of their position in a morphogen gradient
1995 StandoutNatureNobel
Transcriptional activators direct histone acetyltransferase complexes to nucleosomes
1998 Nature
Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE
1991 Nature
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor
1991
The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain
1989
Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.
1993
Mechanism of transcriptional activation by Sp1: Evidence for coactivators
1990
A single glutamic acid residue plays a key role in the transcriptional activation function of lambda repressor
1989
The Role of Human TFIIB in Transcription Start Site Selection in Vitro and in Vivo
1999
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Eukaryotic activators function during multiple steps of preinitiation complex assembly
1993 Nature
DNA topoisomerase I is involved in both repression and activation of transcription
1993 Nature
Cloning of a human gene encoding the general transcription initiation factor IIB
1991 Nature
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID
1992
Isolation and nucleotide sequence of a murine cDNA homologous to human activating transcription factor 4
1991
Family of proteins that interact with TFIID and regulate promoter activity
1991
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian Cells
2016
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
GAL4-VP16 is an unusually potent transcriptional activator
1988 Nature
Histone H1 is located in the interior of the chromatin 30-nm filament
1994 StandoutNatureNobel
Robust, synergistic regulation of human gene expression using TALE activators
2013
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Reduced binding of TFIID to transcriptionally compromised mutants of VP16
1991 Nature
Functional dissection of TFIIB domains required for TFIIB–TFIID–promoter complex formation and basal transcription activity
1993 Nature
Analysis of structure-function relationships of yeast TATA box binding factor TFIID
1990
Mediator and the mechanism of transcriptional activation
2005 StandoutNobel
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo
1992
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein
1988 Nature
DNA recognition by GAL4: structure of a protein-DNA complex
1992 Nature
Mechanism of action of a yeast activator: Direct effect of GAL4 derivatives on mammalian TFIID-promoter interactions
1988
GAL11P: A yeast mutation that potentiates the effect of weak GAL4-derived activators
1990
Transcriptional regulation by the immediate early protein of pseudorabies virus during in vitro nucleosome assembly
1988
Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID
1990 Nature
The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly
1991
Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex
1988
Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor
1991 Nature
Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation
1993 Nature
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains
1992
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB
1993
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
1994 StandoutNobel
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen
1993
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
1994 StandoutNatureNobel
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
1994 StandoutNobel
The fission yeast cdc18+ gene product couples S phase to START and mitosis
1993 StandoutNobel
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB
1994
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors
1990
A novel mediator between activator proteins and the RNA polymerase II transcription apparatus
1990 StandoutNobel
How eukaryotic transcriptional activators work
1988 StandoutNature
Mechanisms of transactivation by retinoic acid receptors
1993
Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID
1990
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
1994 StandoutNatureNobel
Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.
1991
GAL4 Protein: Purification, Association with GAL80 Protein, and Conserved Domain Structure
1990 StandoutNobel
Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.
1990
Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein
1991 Science
An ATP-dependent inhibitor of TBP binding to DNA.
1993
Delineation of two functional regions of transcription factor TFIIB.
1993
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID.
1992
Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.
1990
TFIIB or not TFIIB?
1991 Nature
The transition of RNA polymerase II from initiation to elongation is associated with phosphorylation of the carboxyl-terminal domain of subunit IIa
1989
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.
1993
Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription
1991 Science
Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation.
1993
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection
1994 StandoutScienceNobel
The role of general initiation factors in transcription by RNA polymerase II
1996
Structure and function of the Zn(II) binding site within the DNA-binding domain of the GAL4 transcription factor.
1989
The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.
1991
Differentiation requires continuous regulation.
1991 Nobel
Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.
1988
Transcription initiated by RNA polymerase II and purified transcription factors from liver. Cooperative action of transcription factors tau and epsilon in initial complex formation.
1990
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
1996
Initiation by Yeast RNA Polymerase II at the Adenoviral Major Late Promoter in Vitro
1989 StandoutScienceNobel
Transcription Factor TFIIB Sites Important for Interaction with Promoter-Bound TFIID
1993 Science
Yeast GCN4 transcriptional activator protein interacts with RNA polymerase II in vitro.
1989
Core Promoter-Dependent TFIIB Conformation and a Role for TFIIB Conformation in Transcription Start Site Selection
2002
Yeast Gal11 protein mediates the transcriptional activation signal of two different transacting factors, Gal4 and general regulatory factor I/repressor/activator site binding protein 1/translation upstream factor.
1990
Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein
1990 Science
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.
1991
Cloning and characterization of PSF, a novel pre-mRNA splicing factor.
1993
Purification and characterization of the yeast transcriptional activator GAL4.
1990
Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase
1992 StandoutScienceNobel
Conserved Structures of Mediator and RNA Polymerase II Holoenzyme
1999 StandoutScienceNobel
Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex
1994 Science
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro.
1989 StandoutNobel
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
TFIIA induces conformational changes in TFIID via interactions with the basic repeat.
1992
Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter.
1992
Activation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro
1989 StandoutNobel
The mammalian TFIID protein is present in two functionally distinct complexes.
1991
Transcriptional activation in yeast by the proline-rich activation domain of human CTF1.
1993
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
A Highly Conserved Domain of RNA Polymerase II Shares a Functional Element with Acidic Activation Domains of Upstream Transcription Factors
1994
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
The Mating of a Fly
1994 StandoutScienceNobel
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection.
1991
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Transcriptional regulation of a pair-rule stripe in Drosophila.
1991
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
1994 Nature
Functional domains of transcription factor TFIIB.
1993
Works of Young-Sun Lin being referenced
GAL4 derivatives function alone and synergistically with mammalian activators in vitro
1988
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex
1988
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives
1990 Nature
Mechanism of action of an acidic transcriptional activator in vitro
1991
How different eukaryotic transcriptional activators can cooperate promiscuously
1990 Nature
A Common trans-Acting Factor Is Involved in Transcriptional Regulation of Neurotransmitter Genes by Cyclic AMP
1988