Citation Impact
Citing Papers
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
Insulin-Like Growth Factor-I Receptor Signaling and Resistance to Trastuzumab (Herceptin)
2001
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
IGFBP3mRNA expression in benign and malignant breast tumors
2007
Insulin-Like Growth Factor 2 in Development and Disease: A Mini-Review
2012
IGFBP-3 in epithelial ovarian carcinoma and its association with clinico-pathological features and patient survival
2001
Antiproliferative Action of Vitamin D-Related Compounds and Insulin-Like Growth Factor-Binding Protein 5 Accumulation
1997
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Senescence-messaging secretome: SMS-ing cellular stress
2009
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
The activin axis in liver biology and disease
2006
Prevention by l-arginine and polyamines of delayed development and embryotoxicity caused by chemically-induced diabetes in rats
1999
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer
2003 Standout
The insulin‐like growth factor I system in the rat cerebellum: Developmental regulation and role in neuronal survival and differentiation
1994
Extrinsic regulators of epithelial tumor progression: metalloproteinases
2000
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation.
1994
Hallmarks of aging: An expanding universe
2023 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjects.
1993
The Role of Tubular Epithelial-Mesenchymal Transition in Progressive Kidney Disease
2007
Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases
1995
The Hallmarks of Cancer
2000 Standout
Heterogeneity of Endothelial Cells
1999
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 StandoutNature
The Epigenomics of Cancer
2007 Standout
Insulin-Like Growth Factors (IGFs), IGF Receptors, and IGF-Binding Proteins in Primary Cultures of Prostate Epithelial Cells*
1991
Ischemic renal diseases: New insights into old entities
1998
Analyzing real-time PCR data by the comparative CT method
2008 Standout
The Role of Insulin, Insulin Growth Factor, and Insulin‐Degrading Enzyme in Brain Aging and Alzheimer′s Disease
2005
Serum Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, and Prostate-Specific Antigen as Predictors of Clinical Prostate Cancer
2000
Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF-Binding Protein-3
1999
Role of the Microbiota in Immunity and Inflammation
2014 Standout
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Uterine Insulin-Like Growth Factor-1: Regulation of Expression and Its Role in Estrogen-Induced Uterine Proliferation*
1990
Plasma Insulin-Like Growth Factor-I, Insulin-Like Growth Factor-Binding Proteins, and Prostate Cancer Risk: a Prospective Study
2000
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Insulin-like Growth Factor (IGF)-binding Protein-3 Induces Apoptosis and Mediates the Effects of Transforming Growth Factor-β1 on Programmed Cell Death through a p53- and IGF-independent Mechanism
1997
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
A New Perspective on Therapeutic Inhibition of Advanced Glycation in Diabetic Microvascular Complications: Common Downstream Endpoints Achieved Through Disparate Therapeutic Approaches?
2009
Estradiol and Antiestrogens Regulate a Growth Inhibitory Insulin-like Growth Factor Binding Protein 3 Autocrine Loop in Human Breast Cancer Cells
1996
The microenvironment of the tumour–host interface
2001 StandoutNature
Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis
2001
Mechanisms of Glucocorticoid Action in Bone
2002
Clinical Applications of Research on Angiogenesis
1995 Standout
Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma.
1994
Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders
1994 Standout
Inhibition of Histone Deacetylase Activity by Butyrate
2003
Cell Migration: A Physically Integrated Molecular Process
1996 Standout
TGFβ in Cancer
2008 Standout
Insulin-like growth factor I increases brain growth and central nervous system myelination in tTransgenic mice
1993
Alzheimer's Disease
2010 Standout
PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2
2005
Pancreatic Cancer
2010 Standout
Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria
2010
Mannose 6-phosphate receptors: new twists in the tale
2003
The role of senescent cells in ageing
2014 StandoutNature
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
2000
Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7
2008
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation
2010
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Retinoids: present role and future potential
1999
Enhanced atherosclerosis and kidney dysfunction in eNOS–/–Apoe–/– mice are ameliorated by enalapril treatment
2000 StandoutNobel
Insulin-Like Growth Factor 1 Receptor Targeted Therapeutics: Novel Compounds and Novel Treatment Strategies for Cancer Medicine
2008
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β
2002
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
1993 StandoutNobel
Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus
1991
Cellular Actions of the Insulin-Like Growth Factor Binding Proteins
2002
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt
1997 StandoutScience
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
2010 Standout
Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos.
1992
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
2003
Stromal Expression of Connective Tissue Growth Factor Promotes Angiogenesis and Prostate Cancer Tumorigenesis
2005
A Breaker of Advanced Glycation End Products Attenuates Diabetes-Induced Myocardial Structural Changes
2003
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
A role for insulin-like growth factor binding protein 5 in the antiproliferative action of the antiestrogen ICI 182780.
1996
Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and Management
2004 Standout
The breakdown of pre‐existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
2003
Angiogenesis: role of calcium-mediated signal transduction.
1995
Growth factor involvement in progression of prostate cancer.
1998
Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study
1998 StandoutScience
Tumor cell senescence in cancer treatment.
2003
From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines
2004
Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway
2004
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.
2003
Spermidine in health and disease
2018 StandoutScience
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway
2007
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Renal Connective Tissue Growth Factor Induction in Experimental Diabetes Is Prevented by Aminoguanidine
2002
Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults
2020
Mechanisms of Diabetic Complications
2013 Standout
Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer.
2002
Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma.
1992
Genes Expressed in Human Tumor Endothelium
2000 StandoutScience
Prevention of Accelerated Atherosclerosis by Angiotensin-Converting Enzyme Inhibition in Diabetic Apolipoprotein E–Deficient Mice
2002
WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
1998
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
The IGF axis and programmed cell death
1999
Proliferin Induces Endothelial Cell Chemotaxis through a G Protein-Coupled, Mitogen-Activated Protein Kinase-Dependent Pathway*
1997
The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
2007
Works of Youngman Oh being referenced
Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure.
1994
Characterization of insulin-like growth factor binding proteins of cultured rat astroglial and neuronal cells
1989
Insulinlike Growth Factor-Binding Proteins
1990
IGFBPs and neoplastic models
1997
Synthesis and Characterization of Insulin-like Growth Factor-binding Protein (IGFBP)-7
1996
Insulin and IGF Binding by IGFBP-3 Fragments Derived From Proteolysis, Baculovirus Expression and Normal Human Urine
1998
[Leu27] INSULIN-LIKE GROWTH FACTOR II IS HIGHLY SELECTIVE FOR THE TYPE-II IGF RECEPTOR IN BINDING, CROSS-LINKING AND THYMIDINE INCORPORATION EXPERIMENTS
1991
Enhanced expression of insulin-like growth factor binding protein-3 sensitizes the growth inhibitory effect of anticancer drugs in gastric cancer cells
2002
Igf-independent regulation of breast cancer growth by IGF binding proteins
1998
Expression of the BRL-3A Insulin-like Growth Factor Binding Protein (rBP-30) in the Rat Central Nervous System
1989
Expression of Two Insulin-Like Growth Factor-Binding Proteins in a Human Endometrial Cancer Cell Line: Structural, Immunological, and Genetic Characterization*
1989
Identification of Glycosylated 38-kDa Connective Tissue Growth Factor (IGFBP-Related Protein 2) and Proteolytic Fragments in Human Biological Fluids, and Up-Regulation of IGFBP-rP2 Expression by TGF-β in Hs578T Human Breast Cancer Cells
1998
Ontogeny of Serum Insulin-Like Growth Factor Binding Proteins in the Rat*
1989
Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics
1996
Insulin‐like growth factor binding proteins and their regulation
1994
IDENTIFICATION OF INSULIN-UKE GROWTH FACTOR-BINDING PROTEIN-2 (IGF-BP-2) AND A LOW MOLECULAR WEIGHT IGF-BP IN HUMAN SEMINAL PLASMA
1990
Insulin‐Like Growth Factor Receptors
1991
Characterization of Insulin-Like Growth Factor-Binding Proteins in Cultured Rat Pituitary Cells*
1989
Transforming Growth Factor- β-induced Cell Growth Inhibition in Human Breast Cancer Cells Is Mediated through Insulin-like Growth Factor-binding Protein-3 Action
1995
Effects of sodium butyrate on expression of members of the IGF-binding protein superfamily in human mammary epithelial cells
2001
Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells
2005
Insulin‐like growth factor binding proteins: a proposed superfamily
1999
An important role of glomerular segmental lesions on progression of IgA nephropathy: a multivariate analysis
1995
Butyrate, a Histone Deacetylase Inhibitor, Activates the Human IGF Binding Protein-3 Promoter in Breast Cancer Cells: Molecular Mechanism Involves an Sp1/Sp3 Multiprotein Complex
2001
The Insulin-like Growth Factor Binding Protein Superfamily: New Perspectives
1999
Evidence for Insulin-Like Growth Factor (IGF)-Independent Transcriptional Regulation of IGF Binding Protein-3 by Growth Hormone in SKHEP-1 Human Hepatocarcinoma Cells*
1997
Connective Tissue Growth Factor (IGFBP-rP2) Expression and Regulation in Cultured Bovine Endothelial Cells*
1999
The insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor mediates IGF-II-induced motility in human rhabdomyosarcoma cells.
1992
Recommendations for Nomenclature of the Insulin-Like Growth Factor Binding Protein Superfamily
1998
Characterization of Insulin-Like Growth Factor-Binding Protein-Related Proteins (IGFBP-rPs) 1, 2, and 3 in Human Prostate Epithelial Cells: Potential Roles for IGFBP-rP1 and 2 in Senescence of the Prostatic Epithelium*
2000
The Insulin-Like Growth Factor-Binding Protein (IGFBP) Superfamily*
1999
Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
1997
Mutation of Three Critical Amino Acids of the N-Terminal Domain of IGF-Binding Protein-3 Essential for High Affinity IGF Binding
2001
Connective Tissue Growth Factor/IGF-Binding Protein-Related Protein-2 Is a Mediator in the Induction of Fibronectin by Advanced Glycosylation End-Products in Human Dermal Fibroblasts
2002
Concentrations of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3), IGF, and IGFBP-3 protease activity in cerebrospinal fluid of children with leukemia, central nervous system tumor, or meningitis.
1993
Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells.
1993
Characterization of Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) Binding to Human Breast Cancer Cells: Kinetics of IGFBP-3 Binding and Identification of Receptor Binding Domain on the IGFBP-3 Molecule*
1999
Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition
1993
Differential Effects of Insulin-Like Growth Factor (IGF)-Binding Protein-3 and Its Proteolytic Fragments on Ligand Binding, Cell Surface Association, and IGF-I Receptor Signaling**This research was supported by US Army Grants DAMD17-991-9522 (to G.R.D.) and DAMD17-96-1-6204 and DAMD17-96-1-7204 (to Y.O.H.) and by NIH Grants R01-DK-51513 (to R.G.R.) and CA-58110 (to R.G.R.).
2000
Advanced Glycosylation End Products Up-Regulate Connective Tissue Growth Factor (Insulin-Like Growth Factor-Binding Protein-Related Protein 2) in Human Fibroblasts: A Potential Mechanism for Expansion of Extracellular Matrix in Diabetes Mellitus*
2001
Unraveling Insulin-Like Growth Factor Binding Protein-3 Actions in Human Disease
2009
Generation and Characterization of an IGFBP-7 Antibody: Identification of 31kD IGFBP-7 in Human Biological Fluids and Hs578T Human Breast Cancer Conditioned Media
1997
Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.
1996