Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Gene essentiality and synthetic lethality in haploid human cells
2015 Science
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
In vivo aspects of protein folding and quality control
2016 Science
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
2016 Science
Machine learning predicts new anti-CRISPR proteins
2020 StandoutNobel
Systematic mapping of functional enhancer–promoter connections with CRISPR interference
2016 Science
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
2017
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level
2017
The BioGRID interaction database: 2017 update
2016
A view on drug resistance in cancer
2019 StandoutNature
Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
2017 Nature
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria
2016
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Induced Pluripotent Stem Cells Meet Genome Editing
2016
Post-translational Regulation of Cas9 during G1 Enhances Homology-Directed Repair
2016
Genome-Editing Technologies: Principles and Applications
2016
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
2018
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
A CRISPR toolbox to study virus–host interactions
2017
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes
2016
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
2016
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Genome-scale CRISPR pooled screens
2016
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020 StandoutNobel
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
2018
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Anti-CRISPRdb: a comprehensive online resource for anti-CRISPR proteins
2017
Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines
2018
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
2016
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library
2016
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Synthetic lethality: the road to novel therapies for breast cancer
2016
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
2019 StandoutNature
Synthetic lethality and cancer
2017
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
2017 Nature
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Comprehensive Integration of Single-Cell Data
2019 Standout
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
The U6 snRNA m 6 A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
2017
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors
2016
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
2016
Leveraging big data to transform target selection and drug discovery
2015
Next-Generation Sequencing of Genome-Wide CRISPR Screens
2017
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Prioritizing genes for systematic variant effect mapping
2020
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations
2017
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
2016
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Yorick Post being referenced
Identification and characterization of essential genes in the human genome
2015 Science