Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
Accelerated telomere shortening in response to life stress
2004 StandoutNobel
Involvement of Brca1 in S-Phase and G 2 -Phase Checkpoints after Ionizing Irradiation
2001
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases
2004
Telomeric Protein Pin2/TRF1 as an Important ATM Target in Response to Double Strand DNA Breaks
2001
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a process similar to, but distinct from, cellular DSB repair
2008
The many substrates and functions of ATM
2000
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Interaction of FANCD2 and NBS1 in the DNA damage response
2002
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
2003
Sensing and repairing DNA double-strand breaks
2002
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9‐1‐1 and Rad17‐RFC
2002
Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) Chromatin Association Is an Early Checkpoint Signaling Event
2002
Cell cycle checkpoint signaling through the ATM and ATR kinases
2001 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Mdc1 couples DNA double‐strand break recognition by Nbs1 with its H2AX‐dependent chromatin retention
2004
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Lcd1p Recruits Mec1p to DNA Lesions In Vitro and In Vivo
2002
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest
2002
DNA Damage-dependent and -independent Phosphorylation of the hRad9 Checkpoint Protein
2001
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Checkpoint Arrest Signaling in Response to UV Damage Is Independent of Nucleotide Excision Repair in Saccharomyces cerevisiae
2003
ATM, a central controller of cellular responses to DNA damage
2001
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
2001 StandoutNobel
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
Chromosomal stability and the DNA double-stranded break connection
2001
DNA damage: a trigger of innate immunity but a requirement for adaptive immune homeostasis
2006
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Telomerase and ATM/Tel1p Protect Telomeres from Nonhomologous End Joining
2003 StandoutNobel
The mismatch repair system is required for S-phase checkpoint activation
2002
The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction
2008
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
2001
A unified view of the DNA-damage checkpoint
2002
The DNA damage-dependent intra–S phase checkpoint is regulated by parallel pathways
2002
MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes
2004
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin
2002 StandoutNobel
DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein
2002
Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
2000 StandoutNobel
Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break
2008 StandoutNobel
Functional Link between BLM Defective in Bloom's Syndrome and the Ataxia-telangiectasia-mutated Protein, ATM
2002
MDC1 is required for the intra-S-phase DNA damage checkpoint
2003 Nature
ATM: Genome stability, neuronal development, and cancer cross paths
2001
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
2002
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways
2002
The Rad9–Hus1–Rad1 (9–1–1) clamp activates checkpoint signaling via TopBP1
2007
Recombinational DNA repair and human disease
2002
Human Claspin Is a Ring-shaped DNA-binding Protein with High Affinity to Branched DNA Structures
2004 StandoutNobel
DNA double-strand breaks: signaling, repair and the cancer connection
2001 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Checking on the fork: the DNA-replication stress-response pathway
2002
Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint
2000
Nuclear Retention of ATM at Sites of DNA Double Strand Breaks
2001
DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells11Edited by J. Karn
2001
Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability
2002
Switching and Signaling at the Telomere
2001 StandoutNobel
NFBD1/KIAA0170 Is a Chromatin-associated Protein Involved in DNA Damage Signaling Pathways
2003
A Critical Role for Pin2/TRF1 in ATM-dependent Regulation
2002
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
2009 StandoutNobel
Structures of the Human Rad17-Replication Factor C and Checkpoint Rad 9-1-1 Complexes Visualized by Glycerol Spray/Low Voltage Microscopy
2002 StandoutNobel
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling
2002
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
The Mre11 complex is required for ATM activation and the G2/M checkpoint
2003
The DNA crosslink‐induced S‐phase checkpoint depends on ATR–CHK1 and ATR–NBS1–FANCD2 pathways
2004
Mammalian G1- and S-phase checkpoints in response to DNA damage
2001
Caretaker tumour suppressor genes that defend genome integrity
2002
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
2002
Requirement of the MRN complex for ATM activation by DNA damage
2003
ATP Activates Ataxia-Telangiectasia Mutated (ATM) in Vitro
2003
ATM and ATR: networking cellular responses to DNA damage
2001
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks
2008
Direct DNA binding by Brca1
2001
Direct Activation of the ATM Protein Kinase by the Mre11/Rad50/Nbs1 Complex
2004 Science
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest
2002
Phosphorylation of FANCD2 on Two Novel Sites Is Required for Mitomycin C Resistance
2006
An ATR- and Chk1-Dependent S Checkpoint Inhibits Replicon Initiation following UVC-Induced DNA Damage
2002
ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1
2001
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Apoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2
2004
Chk2 Activation Dependence on Nbs1 after DNA Damage
2001
DNA Damage Processing Defects and Disease
2001
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
2003
Two Molecularly Distinct G2/M Checkpoints Are Induced by Ionizing Irradiation
2002
Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways
2000
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
A DNA Damage-Regulated BRCT-Containing Protein, TopBP1, Is Required for Cell Survival
2002
P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks
2000
Toward Maintaining the Genome: DNA Damage and Replication Checkpoints
2002
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation.
2000
Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
2004
Human DNA Repair Genes
2001 StandoutScienceNobel
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G 1 /S checkpoint activation in response to DNA damage
2001
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Oligomerization of MDC1 Protein Is Important for Proper DNA Damage Response
2011
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Works of Yi-Tzu Lin being referenced
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway
2021
Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest
2000
Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
2000 Nature
ATM-dependent Phosphorylation of Human Rad9 Is Required for Ionizing Radiation-induced Checkpoint Activation
2001