Citation Impact
Citing Papers
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
2015 StandoutNobel
Self‐organized developmental patterning and differentiation in cerebral organoids
2017
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size
2016
Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions
2020 StandoutNobel
Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase
2016 StandoutNobel
Down syndrome and the complexity of genome dosage imbalance
2016
A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
2015
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
2019 Standout
A guide to genome engineering with programmable nucleases
2014 Standout
Induced Pluripotent Stem Cells for Traumatic Spinal Cord Injury
2017
Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development
2013
The emerging role of lncRNAs in cancer
2015 Standout
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Organotypic Neurovascular Models: Past Results and Future Directions
2019
Oxidative stress and the amyloid beta peptide in Alzheimer’s disease
2017 Standout
SnapShot: Directed Differentiation of Pluripotent Stem Cells
2012
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells
2015
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo
2020
Gut microbiome alterations in Alzheimer’s disease
2017 Standout
Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
2014 Standout
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21
2018
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies
2013
Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
2013
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease
2012
Stem cell models of Alzheimer’s disease: progress and challenges
2017
Opportunities and challenges of pluripotent stem cell neurodegenerative disease models
2013
Managing the care of adults with Down's syndrome
2014
Translating dosage compensation to trisomy 21
2013 Nature
Traumatic spinal cord injury
2017 Standout
Reactive Astrocytes: Production, Function, and Therapeutic Potential
2017 Standout
Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
2016 Nature
The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
2014
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
2019
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons
2015
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy
2020 Standout
Down syndrome
2020 Standout
Panax notoginsenoside Rb1 ameliorates Alzheimer’s disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression
2013
Generation of cerebral organoids from human pluripotent stem cells
2014
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Down Syndrome
2020 Standout
Alzheimer's disease
2017 Standout
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
2019 StandoutNobel
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
2022 StandoutNobel
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Modeling human cortical development in vitro using induced pluripotent stem cells
2012
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
2019 Standout
Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
2013
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
2014 Standout
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
2016 StandoutNobel
Human in vitro models for understanding mechanisms of autism spectrum disorder
2020
Works of Yichen Shi being referenced
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
2012
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
2012
A Human Stem Cell Model of Early Alzheimer’s Disease Pathology in Down Syndrome
2012