Standout Papers
Citation Impact
Citing Papers
Temporal calcium profiling of specific circadian neurons in freely moving flies
2017 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
CRY, a Drosophila Clock and Light-Regulated Cryptochrome, Is a Major Contributor to Circadian Rhythm Resetting and Photosensitivity
1998 StandoutNobel
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Direct and continuous assessment by cells of their position in a morphogen gradient
1995 StandoutNatureNobel
Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1)
2004
The role of chemoattraction in cancer metastases
2001
Genetic and Molecular Bases of Neurogenesis in Drosophila Melanogaster
1991
Inflammation and cancer
2002 StandoutNature
Common mechanisms of nerve and blood vessel wiring
2005 Nature
Molecular Cloning and Characterization of an Insect Aquaporin
1996
Inhibition of activin receptor signaling promotes neuralization in Xenopus
1994
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Evolution of the MIP family of integral membrane transport proteins
1991
Dendrites of Distinct Classes of Drosophila Sensory Neurons Show Different Capacities for Homotypic Repulsion
2003
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Phylogenetic Characterization of the MIP Family of Transmembrane Channel Proteins
1996
Alternative RNA splicing in the nervous system
2001
Outer membrane protein folding from an energy landscape perspective
2017
Root-specific genes from tobacco andArabidopsishomologous to an evolutionarily conserved gene family of membrane channel proteins
1990
The three-dimensional structure of aquaporin-1
1997 StandoutNatureNobel
The T-box gene family
1998
Early ventral expression of the Drosophila neurogenic locus mastermind
1991
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
A transcriptional reporter of intracellular Ca2+ in Drosophila
2015
Structural determinants of water permeation through aquaporin-1
2000 StandoutNatureNobel
Tandem sequence repeats in transmembrane channel proteins
1991
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila
1991 StandoutNobel
Genes required for specifying cell fates in Drosophila embryonic sensory nervous system
1990
A role for the Drosophila neurogenic genes in mesoderm differentiation
1991 StandoutNobel
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Control of cell lineage-specific development and transcription by bHLH-PAS proteins
1998
Mutations in the founder of the MIP gene family underlie cataract development in the mouse
1996
Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation
1999
Defective Urinary Concentrating Ability Due to a Complete Deficiency of Aquaporin-1
2001 StandoutNobel
Sequence identification of 2,375 human brain genes
1992 Nature
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
1992 StandoutNatureNobel
Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen
1993
Progress on the Structure and Function of Aquaporin 1
1998 StandoutNobel
A role for axon guidance receptors and ligands in blood vessel development and tumor angiogenesis
2005
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
2006 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Genomic cloning, complete nucleotide sequence, and structure of the human gene encoding the major intrinsic protein (MIP) of the lens
1991
Aquaporin water channels – from atomic structure to clinical medicine
2002 StandoutNobel
Fringe modulates Notch–ligand interactions
1997 Nature
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Angiogenic Signalling Pathways
2008
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
Gap junctions: New tools, new answers, new questions
1991
A brain-specific activator of cyclin-dependent kinase 5
1994 StandoutNatureNobel
T-box genes: what they do and how they do it
1999
The MIP Family of Integral Membrane Channel Proteins: Sequence Comparisons, Evolutionary Relationships, Reconstructed Pathway of Evolution, and Proposed Functional Differentiation of the Two Repeated Halves of the Proteins
1993
Angiogenesis as a therapeutic target
2005 StandoutNature
Predictive evidence for a porin-type β-barrel fold in CHIP28 and other members of the MIP family. A restricted-pore model common to water channels and facilitators
1995
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Markers of vertebrate mesoderm induction
1997 StandoutNobel
GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal Polarity
2005
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products
2010 Standout
Regulation of the Escherichia coli water channel gene aqpZ
1998 StandoutNobel
Mutations in aquaporin-1 in Phenotypically Normal Humans Without Functional CHIP Water Channels
1994 StandoutScienceNobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo
1993
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
The future of cloning
1999 StandoutNatureNobel
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Aquaporin null phenotypes: The importance of classical physiology
1998 StandoutNobel
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.
1994 StandoutNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation
1994
Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm
1996
The human aquaporin-CHIP gene. Structure, organization, and chromosomal localization
1993 StandoutNobel
Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein
1992 StandoutScienceNobel
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues.
1994
Involvement of Pre- and Postsynaptic Mechanisms in Posttetanic Potentiation at Aplysia Synapses
1997 StandoutScienceNobel
Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter.
1994
Cellular and Molecular Biology of the Aquaporin Water Channels
1999 StandoutNobel
Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins.
1991 StandoutNobel
Molecular cloning and expression of a member of the aquaporin family with permeability to glycerol and urea in addition to water expressed at the basolateral membrane of kidney collecting duct cells.
1994
Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress.
1995
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Circadian neuron feedback controls the Drosophila sleep–activity profile
2016 StandoutNatureNobel
Genes controlling cellular polarity in Drosophila
1993
The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers.
1990
Morphogen gradient interpretation
2001 StandoutNatureNobel
Works of Yi Rao being referenced
A subset of octopaminergic neurons are important for Drosophila aggression
2008
Directional guidance of neuronal migration in the olfactory system by the protein Slit
1999 Nature
Vertebrate Slit, a Secreted Ligand for the Transmembrane Protein Roundabout, Is a Repellent for Olfactory Bulb Axons
1999
Mapping Neural Circuits with Activity-Dependent Nuclear Import of a Transcription Factor
2012
Signal Transduction in Neuronal Migration
2001
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors
2001 Nature
Molecular control of neuronal migration
2002
Both the Establishment and the Maintenance of Neuronal Polarity Require Active Mechanisms
2005
Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
2013 Standout
Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins
1990 Nature
Robo4 is a vascular-specific receptor that inhibits endothelial migration
2003
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity
2003
Isolation of Amentoflavone from Selaginella rupestris and its Pharmacological Activity on Central Nervous System, Smooth Muscles and Isolated Frog Heart Preparations
1981
The Secreted Product of Xenopus Gene lunatic Fringe , a Vertebrate Signaling Molecule
1996 Science
Neuroectoderm in Drosophila embryos is dependent on the mesoderm for positioning but not for formation.
1991
A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate
1997
The big brain gene of Drosophila functions to control the number of neuronal precursors in the peripheral nervous system
1992
Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors
1998
Conversion of a mesodermalizing molecule, the Xenopus Brachyury gene, into a neuralizing factor.
1994