Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Acidic Extracellular pH Induces Vascular Endothelial Growth Factor (VEGF) in Human Glioblastoma Cells via ERK1/2 MAPK Signaling Pathway
2002
Hallmarks of Cancer: The Next Generation
2011 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
2000 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Use of Reporter Genes for Optical Measurements of Neoplastic Disease In Vivo
2000
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Role of Carcinoma-Associated Fibroblasts and Hypoxia in Tumor Progression
2010
Dominant-Negative Hypoxia-Inducible Factor-1α Reduces Tumorigenicity of Pancreatic Cancer Cells through the Suppression of Glucose Metabolism
2003
Shedding light onto live molecular targets
2003 Standout
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
2004
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
Suppression of tumor growth through disruption of hypoxia-inducible transcription
2000 StandoutNobel
On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
2001 StandoutNobel
MicroRNAs
2004 Standout
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Clinical translation of angiogenesis inhibitors
2002 Standout
Host tissue determinants of tumour immunity
2019
Host cyclooxygenase-2 modulates carcinoma growth
2000
T Cells and Cancer: How Metabolism Shapes Immunity
2016
Tumor angiogenesis: past, present and the near future
2000
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
2004 Standout
Spying on cancer
2005
The biology and function of fibroblasts in cancer
2016 Standout
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
The biology of VEGF and its receptors
2003 Standout
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo
2005 StandoutNobel
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
2006
Hallmarks of cancer: Interactions with the tumor stroma
2010
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
2006
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
Herceptin acts as an anti-angiogenic cocktail
2002 Nature
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
VEGF as a Key Mediator of Angiogenesis in Cancer
2005
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
2002
Molecular Imaging
2001
Angiogenesis and Lymphangiogenesis in Tumors: Insights from Intravital Microscopy
2002
Dissecting tumour pathophysiology using intravital microscopy
2002
In Vivo Detection of Human Vascular Endothelial Growth Factor Promoter Activity in Transgenic Mouse Skin
2000
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Fibroblasts as architects of cancer pathogenesis
2012
Functional Anatomy of a dsRNA Trigger
2000 StandoutNobel
Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression
2009
Molecular regulation of vessel maturation
2003 Standout
Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis
2014
Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting
2008
Hypoxia: A key regulator of angiogenesis in cancer
2007
Clinical applications of angiogenic growth factors and their inhibitors
1999
In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy
2001
Cellular Activation of the Self-Quenched Fluorescent Reporter Probe in Tumor Microenvironment
2002
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
2002 Standout
Fibroblasts in cancer
2006 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF
2005
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Tumor Angiogenesis
2008 Standout
VEGFs, receptors and angiogenesis
1999
Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke
2001
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.
2000
Transport of Molecules, Particles, and Cells in Solid Tumors
1999
Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
2001
Local imbalance of proangiogenic and antiangiogenic factors: a potential mechanism of focal necrosis and dormancy in tumors.
2000
Life with Oxygen
2007 StandoutScienceNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
2004 Standout
Novel Virulence Gene and Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Multilocus Sequence Typing Scheme for Subtyping of the Major Serovars ofSalmonella entericasubsp.enterica
2011
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors.
2000
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Therapeutic Targeting of the Tumor Microenvironment
2021
Fractals and cancer.
2000
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
2002
Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia.
2001
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Regulation of the anti-tumour immune response by cancer-associated fibroblasts
2014
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor.
2000
Imaging the glycome
2008 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
Angiogenesis in Endocrine Tumors
2003
Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts.
2001
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Chemical Glycoproteomics
2016 StandoutNobel
Works of Yi Chen being referenced
Tumor Induction of VEGF Promoter Activity in Stromal Cells
1998
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.
2001
Multi-Virulence-Locus Sequence Typing Identifies Single Nucleotide Polymorphisms Which Differentiate Epidemic Clones and Outbreak Strains ofListeria monocytogenes
2007