Standout Papers

Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Ac... 2000 2026 2008 2017 301
  1. Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase (2000)
    Pankaj Kapahi, Takayuki Takahashi et al. Journal of Biological Chemistry

Citation Impact

Citing Papers

Acute postnatal ablation of Hif-2 α results in anemia
2007
Hallmarks of Cancer: The Next Generation
2011 Standout
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
2001 Standout
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
A view on drug resistance in cancer
2019 StandoutNature
Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness
2000
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Imaging in the era of molecular oncology
2008 StandoutNature
Tumor angiogenesis: past, present and the near future
2000
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancer
2006 Standout
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
2001 Standout
Imaging angiogenesis of genitourinary tumors
2010
Angiogenesis in cancer and other diseases
2000 StandoutNature
Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1
2006 StandoutNobel
Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia
2014
NF-κB activation by reactive oxygen species: Fifteen years later
2006
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo
2005 StandoutNobel
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
2007
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
2006
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
2005 Standout
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Angiogenesis in life, disease and medicine
2005 StandoutNature
The microenvironment of the tumour–host interface
2001 StandoutNature
Angiogenesis and Lymphangiogenesis in Tumors: Insights from Intravital Microscopy
2002
Dissecting tumour pathophysiology using intravital microscopy
2002
‘Accidental’ anti-angiogenic drugs
2000
Malignant Gliomas in Adults
2008 Standout
Angiogenesis in brain tumours
2007
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
2008 Standout
Imaging angiogenesis and the microenvironment
2008
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre-Clinical Models
2010
Molecular regulation of vessel maturation
2003 Standout
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Coordinated Interaction of Neurogenesis and Angiogenesis in the Adult Songbird Brain
2002
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Symptomatic Intracerebral Hemorrhage following Thrombolytic Therapy for Acute Ischemic Stroke: A Review of the Risk Factors
2007
Mechanisms of angiogenesis and arteriogenesis
2000 Standout
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Imaging of angiogenesis: from microscope to clinic
2003
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
2000
NF-κB as a therapeutic target in cancer
2002
Carboplatin selectively induces the VEGF stress response in endothelial cells: Potentiation of antitumor activity by combination treatment with antibody to VEGF
2004
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
2004 Standout
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
2011
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
1999
Angiogenesis as a therapeutic target
2005 StandoutNature
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects
2002
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.
2000
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
2018 Standout
Transport of Molecules, Particles, and Cells in Solid Tumors
1999
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Hypoxia, Clonal Selection, and the Role of HIF-1 in Tumor Progression
2000 StandoutNobel
Normalization of the Vasculature for Treatment of Cancer and Other Diseases
2011
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis.
2001
Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors.
2000
Fractals and cancer.
2000
Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF
1999 StandoutScience
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
2002
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
Regulation of hypoxia-induced angiogenesis: a chaperone escorts VEGF to the dance
2001 StandoutNobel
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
The Ecology of Arsenic
2003 StandoutScience
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood
2000
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Two-Photon Absorbing Nanocrystal Sensors for Ratiometric Detection of Oxygen
2009 StandoutNobel
Reactive Oxygen Species (ROS), Troublemakers between Nuclear Factor-κB (NF-κB) and c-Jun NH2-terminal Kinase (JNK)
2004
Regulation of angiogenesis via vascular endothelial growth factor receptors.
2000
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Angiogenesis in Endocrine Tumors
2003
Genes Expressed in Human Tumor Endothelium
2000 StandoutScience
Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts.
2001
Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy.
2000
Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers
2013
NF-κB in cancer—a friend turned foe
2004
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
2004 Standout

Works of Yi Chen being referenced

Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase
2000 StandoutNobel
Predictors of Hemorrhagic Transformation After Intravenous Recombinant Tissue Plasminogen Activator
2002
Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: Role of vascular endothelial growth factor
1998
Rankless by CCL
2026