Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Critical Role of Cyclophilin A and Its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the Hepatitis C Virus Replication Complex
2009
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients
2007 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
Intracellular Innate Immune Cascades and Interferon Defenses That Control Hepatitis C Virus
2009
The Guanylate-Binding Proteins: Emerging Insights into the Biochemical Properties and Functions of This Family of Large Interferon-Induced Guanosine Triphosphatase
2010
Identification of interferon-stimulated genes that attenuate Ebola virus infection
2020 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication
2009
Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems
2017 StandoutNobel
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B
2009
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease
2012
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Regulation of hepatic innate immunity by hepatitis C virus
2013
Evasion of intracellular host defence by hepatitis C virus
2005 Nature
Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics
2009
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death
2008
Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir
2016 StandoutNobel
Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents
2011
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
2006 StandoutNobel
Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication
2012
Compensatory mutations in NS3 and NS5A proteins enhance the virus production capability of hepatitis C reporter virus
2009
Metazoan MicroRNAs
2018 Standout
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach
2010
Treating hepatitis C
2005 StandoutNobel
Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
2010
HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A–cyclophilin A interaction to cyclophilin inhibitors
2010
Cyclophilin inhibitors in hepatitis C viral infection
2007
The long and winding road leading to the identification of the hepatitis C virus
2009 StandoutNobel
Cyclophilin B Is a Functional Regulator of Hepatitis C Virus RNA Polymerase
2005
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Hepatitis C virus: How genetic variability affects pathobiology of disease
2011
DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A
2010
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
2017 StandoutNobel
Genetics of IL28B and HCV—response to infection and treatment
2012
Hepatitis C Virus NS5B and Host Cyclophilin A Share a Common Binding Site on NS5A
2012
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
2006
The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A
2010
2′,5′-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro
2010
Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B
2007
Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication?
2007
Measuring HCV Infectivity Produced in Cell Culture and In Vivo
2009
Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes
2009 StandoutNobel
A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication
2009
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Domain 3 of NS5A Protein from the Hepatitis C Virus Has Intrinsic α-Helical Propensity and Is a Substrate of Cyclophilin A
2011
Curing a viral infection by targeting the host: The example of cyclophilin inhibitors
2013
Interferon-stimulated genes and their antiviral effector functions
2011 StandoutNobel
Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8+ T Cell Immune Responses against West Nile Virus Infection
2011
Innate immune responses in hepatitis C virus infection
2012
Innate Immune Responses to Hepatitis C Virus
2013 StandoutNobel
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Calcineurin Inhibitors Stimulate and Mycophenolic Acid Inhibits Replication of Hepatitis E Virus
2014
Replication of hepatitis C virus
2007 StandoutNobel
Entry and replication of recombinant hepatitis C viruses in cell culture
2012
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro†
2006
Characterization of Hepatitis C Virus Subgenomic Replicon Resistance to Cyclosporine In Vitro
2007
Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication
2006
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Combinations of Cyclophilin Inhibitor NIM811 with Hepatitis C Virus NS3-4A Protease or NS5B Polymerase Inhibitors Enhance Antiviral Activity and Suppress the Emergence of Resistance
2008
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells
2006
Novel Mutations in a Tissue Culture-Adapted Hepatitis C Virus Strain Improve Infectious-Virus Stability and Markedly Enhance Infection Kinetics
2011
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
A Short Hairpin RNA Screen of Interferon-Stimulated Genes Identifies a Novel Negative Regulator of the Cellular Antiviral Response
2013
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Debio 025, a Cyclophilin Binding Molecule, Is Highly Efficient in Clearing Hepatitis C Virus (HCV) Replicon-Containing Cells When Used Alone or in Combination with Specifically Targeted Antiviral Therapy for HCV (STAT-C) Inhibitors
2008
NIM811, a Cyclophilin Inhibitor, Exhibits Potent In Vitro Activity against Hepatitis C Virus Alone or in Combination with Alpha Interferon
2006
Response of Hepatitis C Virus to Long-Term Passage in the Presence of Alpha Interferon: Multiple Mutations and a Common Phenotype
2013 StandoutNobel
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Development of a Cell-Based Hepatitis C Virus Infection Fluorescent Resonance Energy Transfer Assay for High-Throughput Antiviral Compound Screening
2009
Proteome Analysis of Liver Cells Expressing a Full-Length Hepatitis C Virus (HCV) Replicon and Biopsy Specimens of Posttransplantation Liver from HCV-Infected Patients
2005
Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro
2008
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naïve hepatitis C patients #
2009
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122
2010
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Safety, pharmacokinetics, and antiviral activity of the cyclophilin inhibitor NIM811 alone or in combination with pegylated interferon in HCV-infected patients receiving 14 days of therapy
2011
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Yasuhiro Itsui being referenced
Association of IL28B variants with response to pegylated‐interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b
2011
Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity
2007
Antiviral effects of the interferon‐induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein†
2009
Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants
2010
Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection
2010
Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3
2006
Suppression of Hepatitis C Virus Replication by Cyclosporin A Is Mediated by Blockade of Cyclophilins
2005
Site‐specific mutation of the interferon sensitivity‐determining region (ISDR) modulates hepatitis C virus replication
2006
Specific inhibition of hepatitis C virus replication by cyclosporin A
2003
Studies on virus kinetics using infectious fluorescence‐tagged hepatitis C virus cell culture
2011
Expressional screening of interferon‐stimulated genes for antiviral activity against hepatitis C virus replication
2006
Hepatitis C virus non-structural proteins responsible for suppression of the RIG-I/Cardif-induced interferon response
2007
Analysis of Interferon Signaling by Infectious Hepatitis C Virus Clones with Substitutions of Core Amino Acids 70 and 91
2011
Regulation of Hepatitis C Virus Replication by Interferon Regulatory Factor 1
2004