Citation Impact
Citing Papers
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
2006
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Tracking of Quantum Dot-labeled CFTR Shows Near Immobilization by C-Terminal PDZ Interactions
2006
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Ubiquitin-binding domains
2006
Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study
2009
The Leucine-rich Repeat Protein LRIG1 Is a Negative Regulator of ErbB Family Receptor Tyrosine Kinases
2004
Hallmarks of Cancer: The Next Generation
2011 Standout
Synergistic Inhibition with a Dual Epidermal Growth Factor Receptor/HER-2/neu Tyrosine Kinase Inhibitor and a Disintegrin and Metalloprotease Inhibitor
2008
Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells
2010 Nature
Endosomal Trafficking During Mitosis and Notch-Dependent Asymmetric Division
2018
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding
2004
Systems Biology of Growth Factor‐Induced Receptor Endocytosis
2008
Specificity in Signal Transduction
2004
A view on drug resistance in cancer
2019 StandoutNature
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Heparin‐binding epidermal growth factor‐like growth factor as a novel targeting molecule for cancer therapy
2006
Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules
2006
Auxiliary‐Mediated Site‐Specific Peptide Ubiquitylation
2007
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Oncogenic kinase signalling
2001 StandoutNature
Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
2004
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance
2004 StandoutNobel
Cell signalling: growth factors and tyrosine kinase receptors
2006
Cysteine Promoted C‐Terminal Hydrazinolysis of Native Peptides and Proteins
2013 StandoutNobel
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
The Presynaptic Active Zone
2012 StandoutNobel
Autophagy-deficient mice develop multiple liver tumors
2011
Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation
2007 StandoutNobel
EGF–ERBB signalling: towards the systems level
2006 Standout
Autophagy: Renovation of Cells and Tissues
2011 Standout
Distinct monoubiquitin signals in receptor endocytosis
2003
Role of the Microbiota in Immunity and Inflammation
2014 Standout
When ubiquitin meets ubiquitin receptors: a signalling connection
2003
Network organization of the human autophagy system
2010 StandoutNature
ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling
2008
STAM and Hrs Are Subunits of a Multivalent Ubiquitin-binding Complex on Early Endosomes
2003
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Role of ubiquitin- and Ubl-binding proteins in cell signaling
2007
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
A Proteomic Analysis of Lysosomal Integral Membrane Proteins Reveals the Diverse Composition of the Organelle
2004
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
2004
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Suppressors of Cytokine Signaling 4 and 5 Regulate Epidermal Growth Factor Receptor Signaling
2004
Endocytosis and intracellular trafficking of ErbBs
2008
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Differential Regulation of EGF Receptor Internalization and Degradation by Multiubiquitination within the Kinase Domain
2006
β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
2007 StandoutNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
Clonal evolution in cancer
2012 StandoutNature
The Hallmarks of Aging
2013 Standout
Metabolism, Cell Surface Organization, and Disease
2009
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site
2012 StandoutNobel
Auxiliary‐Mediated Site‐Specific Peptide Ubiquitylation
2007
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Role of Rab GTPases in Membrane Traffic and Cell Physiology
2011
Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling
2007 Science
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
2008 StandoutScience
Design and Synthesis of 5-Aryl-pyridone-carboxamides as Inhibitors of Anaplastic Lymphoma Kinase
2006
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
Synthetic Analogues of Glycosylphosphatidylinositol-Anchored Proteins and Their Behavior in Supported Lipid Bilayers
2007 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
ADAPTORS FOR CLATHRIN COATS: Structure and Function
2004
Regulating the dynamics of EGF receptor signaling in space and time
2005
A Tale of Two Cbls: Interplay of c-Cbl and Cbl-b in Epidermal Growth Factor Receptor Downregulation
2008
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network
2006
Cancer Genome Landscapes
2013 StandoutScience
Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking
2007
Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane
2004
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
Neurotransmitter release regulated by a MALS–liprin-α presynaptic complex
2005
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
Vps27 recruits ESCRT machinery to endosomes during MVB sorting
2003
Works of Yaron Mosesson being referenced
Hsp90 restrains ErbB‐2/HER2 signalling by limiting heterodimer formation
2004
Polar Expression of ErbB-2/HER2 in Epithelia
2003
Conjugation to Nedd8 Instigates Ubiquitylation and Down-regulation of Activated Receptor Tyrosine Kinases
2006
Derailed endocytosis: an emerging feature of cancer
2008
Oncogenic growth factor receptors: implications for signal transduction therapy
2004
Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation
2003
Ligand‐Independent Degradation of Epidermal Growth Factor Receptor Involves Receptor Ubiquitylation and Hgs, an Adaptor Whose Ubiquitin‐Interacting Motif Targets Ubiquitylation by Nedd4
2002