Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
2009
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Extracellular vesicles and particles impact the systemic landscape of cancer
2022
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor
2015
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Switchable Cas9
2017 StandoutNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
The EF-hand Ca2+ Binding Domain Is Not Required for Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor
2015
Germline development from human pluripotent stem cells toward disease modeling of infertility
2012 StandoutNobel
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
2017 Standout
Mass spectrometry guided structural biology
2016
NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus
2018 StandoutNobel
The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy
2019 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Gating machinery of InsP3R channels revealed by electron cryomicroscopy
2015 Nature
Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel
2019
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Molecular Dynamics Simulation for All
2018 Standout
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
New insights into apoptosome structure and function
2018
Mechanism of anti-angiogenic property of gold nanoparticles: role of nanoparticle size and surface charge
2011
Electron cryo-microscopy structure of the mechanotransduction channel NOMPC
2017 Nature
The Novel Activity of Carbamazepine as an Activation Modulator Extends from NaV1.7 Mutations to the NaV1.8-S242T Mutant Channel from a Patient with Painful Diabetic Neuropathy
2018
Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
2018 Nature
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel
2020
Prognostic significance of nemo-like kinase in nasopharyngeal carcinoma
2014
Single-Particle Cryo-EM at Crystallographic Resolution
2015
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM
2017
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
Induced pluripotent stem cells and reprogramming: seeing the science through the hype
2009 StandoutNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Crystal structure of the epithelial calcium channel TRPV6
2016 Nature
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
2020 Standout
Building de novo cryo-electron microscopy structures collaboratively with citizen scientists
2019 StandoutNobel
Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling
2017
Mitochondria as multifaceted regulators of cell death
2019 Standout
In vitro cell migration and invasion assays
2012
Molecular tuning of electroreception in sharks and skates
2018 StandoutNatureNobel
Structural Prediction of Peptide–MHC Binding Modes
2022
Oxidative stress response and Nrf2 signaling in aging
2015
Epithelial-mesenchymal transition in glioblastoma progression
2016
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant
2015
Reassessment of Exosome Composition
2019 Standout
Gold nanoparticles in biomedical applications: recent advances and perspectives
2011 Standout
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
2016
Photoreceptor engineering
2015
Mechanisms guiding primordial germ cell migration: strategies from different organisms
2009
Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19
2020
Evolutionary Pressure against MHC Class II Binding Cancer Mutations
2018
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
SARS-CoV-2 vaccines in development
2020 StandoutNature
Exosomes
2019 Standout
Enhanced SARS-CoV-2 neutralization by dimeric IgA
2020 StandoutNobel
MHCAttnNet: predicting MHC-peptide bindings for MHC alleles classes I and II using an attention-based deep neural model
2020
Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy
2017
Improved Prediction of MHC II Antigen Presentation through Integration and Motif Deconvolution of Mass Spectrometry MHC Eluted Ligand Data
2020
Sodium Channels in Human Pain Disorders: Genetics and Pharmacogenomics
2019
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Cryo-Electron Microscopy and the Amazing Race to Atomic Resolution
2015
DeepLigand: accurate prediction of MHC class I ligands using peptide embedding
2019
The Role of Voltage-Gated Sodium Channels in Pain Signaling
2019
Mechanisms and functions of p38 MAPK signalling
2010
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
2023 StandoutNobel
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET
2017
NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand data
2020
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
The Cation−π Interaction
2012
Comparative sequence analysis suggests a conserved gating mechanism for TRP channels
2015
Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations
2019 StandoutNobel
Iterative Molecular Dynamics–Rosetta Membrane Protein Structure Refinement Guided by Cryo-EM Densities
2017
Crystal structures of claudins: insights into their intermolecular interactions
2017
Works of Yan Zhen being referenced
Structure of the voltage-gated calcium channel Ca v 1.1 complex
2015 Science
The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
2016
Structural basis of ultraviolet-B perception by UVR8
2012 Nature
ZEB2 Mediates Multiple Pathways Regulating Cell Proliferation, Migration, Invasion, and Apoptosis in Glioma
2012
Germ cell‐less expression in zebrafish embryos
2006
Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution
2014 Nature
Reduced CTGF Expression Promotes Cell Growth, Migration, and Invasion in Nasopharyngeal Carcinoma
2013
Structure of the Nav1.4-β1 Complex from Electric Eel
2017
Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma
2013
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
2016 Nature
Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
2007
Phosphorylation of Fibroblast Growth Factor (FGF) Receptor 1 at Ser777 by p38 Mitogen-Activated Protein Kinase Regulates Translocation of Exogenous FGF1 to the Cytosol and Nucleus
2008
Cellular functions of Rab GTPases at a glance
2015
Size Limitation in Translocation of Fibroblast Growth Factor 1 Fusion Proteins across the Endosomal Membrane
2009
IEDB-AR: immune epitope database—analysis resource in 2019
2019
An automated benchmarking platform for MHC class II binding prediction methods
2017
Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome
2014
Improved methods for predicting peptide binding affinity to MHC class II molecules
2018