Standout Papers
Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Regulation of Blood and Lymphatic Vascular Separation by Signaling Proteins SLP-76 and Syk
2003 Science
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green
2018 StandoutNobel
Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis
2008
Vascular Endothelial Growth Factor-A Promotes Peritumoral Lymphangiogenesis and Lymphatic Metastasis
2005
Tumor-Secreted Vascular Endothelial Growth Factor-C Is Necessary for Prostate Cancer Lymphangiogenesis, but Lymphangiogenesis Is Unnecessary for Lymph Node Metastasis
2005
The Lymphatic System in Health and Disease
2008
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization
2010
Developmental and pathological lymphangiogenesis: from models to human disease
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche
2012
Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand
2002 Standout
Pathways mediating VEGF-independent tumor angiogenesis
2009
Tumor-targeting peptides from combinatorial libraries
2016
Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity
2006
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
2013 Nature
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
2005 Standout
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
2010
B Cell-Driven Lymphangiogenesis in Inflamed Lymph Nodes Enhances Dendritic Cell Mobilization
2006
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Robo4 Cooperates with Cxcr4 to Specify Hematopoietic Stem Cell Localization to Bone Marrow Niches
2011
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
Regulation of angiogenesis by the aging suppressor gene klotho
2002
Tumor metastasis and the lymphatic vasculature
2009
Lymphatic endothelium in health and disease
2008
Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1
2009
Increased skeletal VEGF enhances β‐catenin activity and results in excessively ossified bones
2009
Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: Contrasting, overlapping and compensatory functions
2009
Endogenous LXA4 Circuits Are Determinants of Pathological Angiogenesis in Response to Chronic Injury
2009
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells
2009
Glioblastoma stem-like cells give rise to tumour endothelium
2010 Nature
The role of myeloid cells in the promotion of tumour angiogenesis
2008
Involvement of endothelial progenitor cells in tumor vascularization
2010
Integrins in angiogenesis and lymphangiogenesis
2008
Systems Biology of Vascular Endothelial Growth Factors
2008
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
2005
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
2012 StandoutNobel
Antiangiogenic Therapy for Cancer: An Update
2007
ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading
2010
Cellular abnormalities of blood vessels as targets in cancer
2004
The biology of VEGF and its receptors
2003 Standout
Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche
2004 Standout
Id proteins in development, cell cycle and cancer
2003
A New Weapon for Attacking Tumor Blood Vessels
2008 StandoutNobel
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
2006
Angiogenesis in health and disease
2003 Standout
Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels
2007
Lymphangiogenic Growth Factor Responsiveness Is Modulated by Postnatal Lymphatic Vessel Maturation
2006
Mechanisms of resistance to antiangiogenesis therapy
2010
Follicular B helper T cells in antibody responses and autoimmunity
2005
VEGF receptor signalling ? in control of vascular function
2006 Standout
Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases
2006
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
2010 Nature
Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development
2010
Endothelial Progenitor Cells
2004
TGF-β1is a negative regulator of lymphatic regeneration during wound repair
2008
Lymphangiogenic growth factors, receptors and therapies
2003
VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells
2006
The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
2011
PDGF and Vessel Maturation
2009
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Myeloid Cells Contribute to Tumor Lymphangiogenesis
2009
Emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis
2005
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
2010
Comparative biology of mouse versus human cells: modelling human cancer in mice
2003
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
2006
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Identification of a clonally expanding haematopoietic compartment in bone marrow
2012
The multifaceted circulating endothelial cell in cancer: towards marker and target identification
2006
Stem cells in tumor angiogenesis
2010
Can tumor angiogenesis be inhibited without resistance?
2005
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
VEGF-targeted therapy: mechanisms of anti-tumour activity
2008 Standout
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
2005
Elusive Identities and Overlapping Phenotypes of Proangiogenic Myeloid Cells in Tumors
2010
HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion
2008
The SDF-1–CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis
2007
Radial glia require PDGFD–PDGFRβ signalling in human but not mouse neocortex
2014 Nature
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
2005
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
2004
Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells
2010
The Link between Lymphatic Function and Adipose Biology
2008
The biology of vascular endothelial growth factors
2005
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells
2007
Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: Implications for tumor progression
2008
Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model
2008
Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
2010
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Ingression of primary mesenchyme cells of the sea urchin embryo: A precisely timed epithelial mesenchymal transition
2007
Endothelium-Microenvironment Interactions in the Developing Embryo and in the Adult
2007
PDGFRβ+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
2005
Lymphangiogenesis and lymphatic metastasis in breast cancer
2009
Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications
2007
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells
2010
Molecular and cellular biomarkers for angiogenesis in clinical oncology
2007
Cancer-related inflammation
2008 StandoutNature
Predicting the outcome of chemotherapy for lung cancer
2006
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Arteriolar niches maintain haematopoietic stem cell quiescence
2013 Nature
Id family of helix-loop-helix proteins in cancer
2005
Syk and Slp-76 Mutant Mice Reveal a Cell-Autonomous Hematopoietic Cell Contribution to Vascular Development
2006
Modes of resistance to anti-angiogenic therapy
2008 Standout
Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment
2013
Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
2012
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Angiogenesis as a therapeutic target
2005 StandoutNature
FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
2008
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
2007 Standout
Tumorigenesis and the angiogenic switch
2003 Standout
Impairment in Ischemia-Induced Neovascularization in Diabetes
2004
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
2003
Molecular Biology and Pathology of Lymphangiogenesis
2008 Standout
The journey of developing hematopoietic stem cells
2006
Preexisting Lymphatic Endothelium but not Endothelial Progenitor Cells Are Essential for Tumor Lymphangiogenesis and Lymphatic Metastasis
2004
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
2005
Bone and the hematopoietic niche: a tale of two stem cells
2011
Young Adult Bone Marrow–Derived Endothelial Precursor Cells Restore Aging-Impaired Cardiac Angiogenic Function
2002
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Inhibition of Natural Type I IFN-Producing and Dendritic Cell Development by a Small Molecule Receptor Tyrosine Kinase Inhibitor with Flt3 Affinity
2005
Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications
2011
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
2010 StandoutNobel
Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
2007
The relationship between bone, hemopoietic stem cells, and vasculature
2011
Vascular Endothelial Growth Factor Signaling Pathways: Therapeutic Perspective
2006
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Tumor Stromal-Derived Factor-1 Recruits Vascular Progenitors to Mitotic Neovasculature, where Microenvironment Influences Their Differentiated Phenotypes
2006
Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression
2010
VEGF-C–induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
2006
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-κB and Prox1
2009
Implications of B7-H1 Expression in Clear Cell Carcinoma of the Kidney for Prognostication and Therapy
2007
Tumor and lymph node lymphangiogenesis—impact on cancer metastasis
2006
Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells
2004
Lymphotoxin β receptor signaling is required for inflammatory lymphangiogenesis in the thyroid
2007
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
2005
Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
2006 Science
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Imaging Steps of Lymphatic Metastasis Reveals That Vascular Endothelial Growth Factor-C Increases Metastasis by Increasing Delivery of Cancer Cells to Lymph Nodes: Therapeutic Implications
2006
Angiogenesis
2006
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Regulation of Bone Marrow-Derived Vascular Progenitor Cell Mobilization and Maintenance
2010
Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease
2004
Endothelial Progenitor Cells
2004 Standout
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells
2012
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Roles for Growth Factors in Cancer Progression
2010
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Age Decreases Endothelial Progenitor Cell Recruitment Through Decreases in Hypoxia-Inducible Factor 1α Stabilization During Ischemia
2007
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
2007
Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease
2004
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
2004 Standout
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Works of Yan Wu being referenced
A fully human monoclonal antibody against VEGFR-1 inhibits growth of human breast cancers
2004
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment
2002
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
2001 Standout
Vascular endothelial growth factor receptor‐1 in human cancer
2010
Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells
2009
Complete and Specific Inhibition of Adult Lymphatic Regeneration by a Novel VEGFR-3 Neutralizing Antibody
2005
Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration
2000
The vascular endothelial growth factor receptor (VEGFR‐1) supports growth and survival of human breast carcinoma
2006
VEGF and VEGFR-2 (KDR) internalization is required for endothelial recovery during wound healing
2007
Monoclonal antibody strategies to block angiogenesis
2001
Vascular endothelial growth factor receptor‐1 promotes migration and invasion in pancreatic carcinoma cell lines
2005
VEGF signaling on hematopoietic precursors restricts B-lymphoid commitment in vitro and in vivo
2008
Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision
2006
Vascular Endothelial Growth Factor Receptor-1 Activation Mediates Epithelial to Mesenchymal Transition in Human Pancreatic Carcinoma Cells
2006
Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias
2001
Identification of high-affinity VEGFR3-binding peptides through a phage-displayed random peptide library
2015
Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo
2004
Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia
2004
Anti-Vascular Endothelial Growth Factor Receptor-1 Antagonist Antibody as a Therapeutic Agent for Cancer
2006
Platelet-Derived Growth Factor Receptor-β Constitutive Activity Promotes Angiogenesis In Vivo and In Vitro
2007
Inhibition of VEGFR-3 Activation with the Antagonistic Antibody More Potently Suppresses Lymph Node and Distant Metastases than Inactivation of VEGFR-2
2006
Vascular endothelial growth factor receptor 3 in hypoxia‐induced vascular development
2004
Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells
2005
Blockade of Vascular Endothelial Growth Factor Receptor I (VEGF-RI), but not VEGF-RII, Suppresses Joint Destruction in the K/BxN Model of Rheumatoid Arthritis
2003
VEGFR-1 (FLT-1) activation modulates acute lymphoblastic leukemia localization and survival within the bone marrow, determining the onset of extramedullary disease
2005