Citation Impact
Citing Papers
Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells
2014
Outcomes in refractory diffuse large B-cell lymphoma: results from the international SCHOLAR-1 study
2017 Standout
Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants
2017
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Phase I Hepatic Immunotherapy for Metastases Study of Intra-Arterial Chimeric Antigen Receptor–Modified T-cell Therapy for CEA+ Liver Metastases
2015
The Basic Principles of Chimeric Antigen Receptor Design
2013
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
CD19-targeted CAR T-cell therapeutics for hematologic malignancies: interpreting clinical outcomes to date
2016
Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells
2015
The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity
2014
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results
2012
Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells
2011
Adoptive T-Cell Therapy for Cancer
2016
Chimeric antigen receptor -T cell therapy: Applications and challenges in treatment of allergy and asthma
2019
Guidelines for the welfare and use of animals in cancer research
2010 Standout
Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
2010 Standout
Cancer treatment and survivorship statistics, 2022
2022 Standout
Control of Regulatory T Cells by Co-signal Molecules
2019 StandoutNobel
Effective Targeting of TAG72+ Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells
2018
In Vivo Cellular Imaging for Translational Medical Research
2009
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy
2014
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
2022 StandoutNobel
Guided by the light: visualizing biomolecular processes in living animals with bioluminescence
2009
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
Clinical lessons learned from the first leg of the CAR T cell journey
2019
Designing chimeric antigen receptors to effectively and safely target tumors
2015
Hallmarks of aging: An expanding universe
2023 Standout
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs
2021 StandoutNobel
Hepatocellular carcinoma
2021 Standout
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection
2013
Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo
2018
Seeing (and Using) the Light: Recent Developments in Bioluminescence Technology
2020
Delivery technologies for cancer immunotherapy
2019 Standout
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
2011 Standout
A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer
2015
Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method
2009
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
Biodistribution and function of extracellular miRNA-155 in mice
2015 StandoutNobel
Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy
2010 Standout
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo
2020
IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo
2015
Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo
2009
Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors
2013
CAR T‐cell immunotherapy: The path from the by‐road to the freeway?
2015
CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response
2019
Engineering CAR-T cells: Design concepts
2015
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo
2015
Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell–mediated Tumor Eradication
2009
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Manufacturing Validation of Biologically Functional T Cells Targeted to CD19 Antigen for Autologous Adoptive Cell Therapy
2009
The pharmacology of second-generation chimeric antigen receptors
2015
Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy
2016
Senolytic CAR T cells reverse senescence-associated pathologies
2020 Nature
Cancer immunotherapy comes of age
2011 StandoutNature
CAR-T cell therapy: current limitations and potential strategies
2021 Standout
A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects
2018
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
2016
Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy
2011
The promise and potential pitfalls of chimeric antigen receptors
2009
Driving CAR T-cells forward
2016
Engineering strategies to overcome the current roadblocks in CAR T cell therapy
2019
Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment
2017
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
2014 Standout
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
De novo design of tyrosine and serine kinase-driven protein switches
2021 StandoutNobel
Agonists of Co-stimulation in Cancer Immunotherapy Directed Against CD137, OX40, GITR, CD27, CD28, and ICOS
2015
Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells
2015
Driving gene-engineered T cell immunotherapy of cancer
2016
Chimeric antigen receptor T-cell therapy — assessment and management of toxicities
2017 Standout
The Emerging Role of In Vitro-Transcribed mRNA in Adoptive T Cell Immunotherapy
2019 StandoutNobel
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Construction and Preclinical Evaluation of an Anti-CD19 Chimeric Antigen Receptor
2009
Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response
2018 StandoutNobel
4-1BB and CD28 Signaling Plays a Synergistic Role in Redirecting Umbilical Cord Blood T Cells Against B-Cell Malignancies
2009
Regimen-Specific Effects of RNA-Modified Chimeric Antigen Receptor T Cells in Mice with Advanced Leukemia
2013
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity
2014
Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling
2011
PD-1– and CTLA-4–Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses
2013
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia
2011 Standout
Acute Myeloid Leukemia
2015 Standout
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
2011
Current concepts in the diagnosis and management of cytokine release syndrome
2014 Standout
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
2023 StandoutNobel
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Supercharging adoptive T cell therapy to overcome solid tumor–induced immunosuppression
2019
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
2012
Chimeric antigen receptors for T cell immunotherapy: current understanding and future directions
2012
Shining Light on the Secreted Luciferases of Marine Copepods: Current Knowledge and Applications
2018
Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
2018 Standout
Chimeric Antigen Receptor Therapy
2018 Standout
Cancer treatment and survivorship statistics, 2019
2019 Standout
Mechanogenetics for the remote and noninvasive control of cancer immunotherapy
2018
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
CD19-Targeted CAR T cells as novel cancer immunotherapy for relapsed or refractory B-cell acute lymphoblastic leukemia.
2016
The Future Is Now: Chimeric Antigen Receptors as New Targeted Therapies for Childhood Cancer
2012
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
2016
Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor
2008
Multimodality imaging of TGFβ signaling in breast cancer metastases
2009
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering
2023 StandoutNobel
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
In vivoInhibition of Human CD19-Targeted Effector T Cells by Natural T Regulatory Cells in a Xenotransplant Murine Model of B Cell Malignancy
2011
Works of Yan Nikhamin being referenced
Successful Eradication of Established Peritoneal Ovarian Tumors in SCID-Beige Mice following Adoptive Transfer of T Cells Genetically Targeted to the MUC16 Antigen
2010
Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression
2015
Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase
2009
Multifactorial Optimization of Gammaretroviral Gene Transfer into Human T Lymphocytes for Clinical Application
2007
Genetically Targeted T Cells Eradicate Systemic Acute Lymphoblastic Leukemia Xenografts
2007