Citation Impact
Citing Papers
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
2009 StandoutScience
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAs in Vitro and in VivoIndependently of Its Ability to Inhibit the dsRNA-dependent Kinase PKR
2003
The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I
2005
IFN-λ: Novel Antiviral Cytokines
2006
To Interfere and to Anti-interfere: The Interplay Between Hepatitis C Virus and Interferon
2002
PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator
2014
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
1997 StandoutNature
PACT, a protein activator of the interferon-induced protein kinase, PKR
1998
Protein–Nucleic Acid Interactions and Cellular Responses to Interferon
1998
Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene
2004
Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR
1997
Inflammation and metabolic disorders
2006 StandoutNature
Interferon-induced Mx proteins in antiviral host defense
2007
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
2002 StandoutNature
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β induction
2003
Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway
1997
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
1998
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β
2002 Nature
Cell Type-Specific Involvement of RIG-I in Antiviral Response
2005
Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways
1997
Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L
1997
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
2003
The Emerging Role of the Interferon-Induced PKR Protein Kinase as an Apoptotic Effector: A New Face of Death?
1999
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Vaccinia Virus E3L Protein Is an Inhibitor of the Interferon (IFN)-Induced 2-5A Synthetase Enzyme
1998
Regulation of IFN‐α/β genes: evidence for a dual function of the transcription factor complex ISGF3 in the production and action of IFN‐α/β
1996
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors
2006
Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR
1999
Molecular Mechanisms of Interferon Resistance Mediated by Viral-Directed Inhibition of PKR, the Interferon-Induced Protein Kinase
1998
Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis
2001
Reoviruses and the Interferon System
1998
Translational control in cancer
2010
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Regulatable Expression of the Interferon-Induced Double-Stranded RNA Dependent Protein Kinase PKR Induces Apoptosis and Fas Receptor Expression
1999
Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis
2010
The growing family of interferon regulatory factors
1997
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1999 StandoutNature
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300
1998
Osteoclast differentiation and activation
2003 StandoutNature
Activation of the interferon system by short-interfering RNAs
2003
Regulation of Antiviral Innate Immune Responses by RIG-I Family of RNA Helicases
2007
Protein Kinase R (PKR) Interacts with and Activates Mitogen-activated Protein Kinase Kinase 6 (MKK6) in Response to Double-stranded RNA Stimulation
2004
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
2003 Nature
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Structure and Function of the Protein Kinase R
2007
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappa B
1997
Revealing the world of RNA interference
2004 StandoutNatureNobel
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
PKR Transduces MDA5-Dependent Signals for Type I IFN Induction
2016
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
2006 StandoutNature
Induction of IRF‐3/‐7 kinase and NF‐κB in response to double‐stranded RNA and virus infection: common and unique pathways
2001
Essential Role for the dsRNA-Dependent Protein Kinase PKR in Innate Immunity to Viral Infection
2000
Reading the viral signature by Toll-like receptors and other pattern recognition receptors
2005
A Model for the Double-stranded RNA (dsRNA)-dependent Dimerization and Activation of the dsRNA-activated Protein Kinase PKR
1997
Nasal Immunization with Anthrax Protective Antigen Protein Adjuvanted with Polyriboinosinic–Polyribocytidylic Acid Induced Strong Mucosal and Systemic Immunities
2006
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling
1998
Cell Growth Regulatory and Antiviral Effects of the P69 Isozyme of 2−5 (A) Synthetase
2000
Type I Interferon Induction Pathway, but Not Released Interferon, Participates in the Maturation of Dendritic Cells Induced by Negative‐Strand RNA Viruses
2003
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages
2002
Endoplasmic Reticulum Stress Signaling in Disease
2006
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Activation of the IFN-Inducible Enzyme RNase L Causes Apoptosis of Animal Cells
1997
Autophagy in immunity and inflammation
2011 StandoutNature
Pathogen Recognition and Innate Immunity
2006 Standout
Interferon-inducible antiviral effectors
2008 Standout
Interferon Action in Triply Deficient Mice Reveals the Existence of Alternative Antiviral Pathways
1999
Toll-Like Receptors
2003 Standout
Regulation of PKR and IRF-1 during hepatitis C virus RNA replication
2002
Influenza Virus NS1 Protein Counteracts PKR-Mediated Inhibition of Replication
2000
The dsRNA binding protein family: critical roles, diverse cellular functions
2003
Functional classification of interferon-stimulated genes identified using microarrays
2001
Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 Are Subunits of Double-Stranded RNA-Activated Transcription Factor DRAF1
1998
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
1997
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Human Immunodeficiency Virus Type 1 Tat Protein Activates Transcription Factor NF-κB through the Cellular Interferon-Inducible, Double-Stranded RNA-Dependent Protein Kinase, PKR
1999
Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection
1996
Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA
1999
Biologic consequences of Stat1-independent IFN signaling
2001
Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene
2000
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
RNA-Dependent Protein Kinase PKR Is Required for Activation of NF-κB by IFN-γ in a STAT1-Independent Pathway
2001
Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase
1999
Antiviral Actions of Interferons
2001 Standout
Translational Control of Viral Gene Expression in Eukaryotes
2000
Global Gene Expression Profiling Reveals Widespread yet Distinctive Translational Responses to Different Eukaryotic Translation Initiation Factor 2B-Targeting Stress Pathways
2005
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
CELLULAR RESPONSES TO INTERFERON-γ
1997 Standout
Inhibition of Replication of Reactivated Human Immunodeficiency Virus Type 1 (HIV-1) in Latently Infected U1 Cells Transduced with an HIV-1 Long Terminal Repeat-Driven PKR cDNA Construct
1999
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
NF-κB Activation by Double-Stranded-RNA-Activated Protein Kinase (PKR) Is Mediated through NF-κB-Inducing Kinase and IκB Kinase
2000
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes
2004 StandoutScience
Increased Susceptibility to DNA Virus Infection in Mice with a GCN2 Mutation
2011 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Sendai Virus C Proteins Must Interact Directly with Cellular Components To Interfere with Interferon Action
2000
Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
2003
Impact of Protein Kinase PKR in Cell Biology: from Antiviral to Antiproliferative Action
2006
PKR-Dependent and -Independent Mechanisms Are Involved in Translational Shutoff during Sindbis Virus Infection
2004 StandoutNobel
Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control
1998
The Murine Double-Stranded RNA-Dependent Protein Kinase PKR Is Required for Resistance to Vesicular Stomatitis Virus
2000
TLR3 Is Essential for the Induction of Protective Immunity against Punta Toro Virus Infection by the Double-Stranded RNA (dsRNA), Poly(I:C12U), but not Poly(I:C): Differential Recognition of Synthetic dsRNA Molecules
2007
Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection
2003
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
When Translation Meets Metabolism: Multiple Links to Diabetes
2003
The Apoptosis Pathway Triggered by the Interferon-Induced Protein Kinase PKR Requires the Third Basic Domain, Initiates Upstream of Bcl-2, and Involves ICE-like Proteases1
1997
Sendai Virus C Proteins Counteract the Interferon-Mediated Induction of an Antiviral State
1999
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Y. Yang being referenced
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.
1995