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Citing Papers
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Kinetic and spectroscopic studies of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II
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Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with l-histidine as a platform for the design of stronger activators
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Structure and mechanism of carbonic anhydrase
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Positions of His‐64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors
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“Designer Acids”: Combined Acid Catalysis for Asymmetric Synthesis
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Is cyanate a carbonic anhydrase substracte?
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1991
Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds
2006
Multiple roles of cysteine in biocatalysis
2003
Fine tuning of the catalytic properties of carbonic anhydrase
1990
At the Crossroads of Chemistry and Immunology: Catalytic Antibodies
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A DNA metalloenzyme with DNA ligase activity
1995 StandoutNatureNobel
Dynamics and mechanism of repair of ultraviolet-induced (6–4) photoproduct by photolyase
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Ligand selectivity and competition between enzymes in silico
2004
Crystallographic studies of inhibitor binding sites in human carbonic anhydrase II: A pentacoordinated binding of the SCN− ion to the zinc at high pH
1988
Dynamics of biochemical and biophysical reactions: insight from computer simulations
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Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Refined structure of human carbonic anhydrase II at 2.0 Å resolution
1988
Hydroxyurea is a carbonic anhydrase inhibitor
2003
Hydration of carbon dioxide by carbonic anhydrase: internal protein transfer of zinc(2+)-bound bicarbonate
1987 Nobel
Catalytic promiscuity and the evolution of new enzymatic activities
1999
Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions
1992
Inactivation of Interleukin-1.beta. Converting Enzyme by Peptide (Acyloxy)methyl Ketones
1994
Changing the efficiency and specificity of the esterase activity of human carbonic anhydrase II by site‐specific mutagenesis
1999
Substrate proton of the pyruvate kinase reaction
1989 StandoutNobel
Increasing Binding Constants of Ligands to Carbonic Anhydrase by Using "Greasy Tails"
1995
Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) Isozymes
2000
Inhibition of Human Erythrocyte Carbonic Anhydrase B by Chloroacetyl Sulfonamides with Labeling of the Active Site
1967
Reply to Karplus: Conformational dynamics have no role in the chemical step
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The Catalytic Mechanism of Carbonic Anhydrase. Hydrogen-Isotope Effects on the Kinetic Parameters of the Human C Isoenzyme
1975
Exploring 12‘-Apo-β-carotenoic-12‘-acid as an Ultrafast Polarity Probe for Ionic Liquids
2008
Binding of substrate CO2 to the active site of human carbonic anhydrase II: a molecular dynamics study.
1990 Nobel
Catalysis of the Hydrolysis of 1-Fluoro-2,4-dinitrobenzene by Carbonic Anhydrase
1968
Molar Scale Synthesis of Enantiopure Stilbene Oxide
1996 StandoutNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
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Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
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Density functional study of symmetric proton transfers
1994
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Supramolecular Chemistry: Receptors, Catalysts, and Carriers
1985 StandoutScienceNobel
Determinants of catalytic activity and stability of carbonic anhydrase II as revealed by random mutagenesis.
1993
Bone Resorption by Osteoclasts
2000 StandoutScience
Molecular Recognition in Anion Coordination Chemistry. Structure, Binding Constants and Receptor‐Substrate Complementarity of a Series of Anion Cryptates of a Macrobicyclic Receptor Molecule
1984
Ultrafast solvation dynamics at binding and active sites of photolyases
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Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study
2008
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121.
1991
A Mild and Efficient Method for the Stereoselective Formation of C−O Bonds: Palladium-Catalyzed Allylic Etherification Using Zinc(II) Alkoxides
2002
Apparent NAC Effect in Chorismate Mutase Reflects Electrostatic Transition State Stabilization
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Design of a new selective cysteine protease inactivator and its mechanistic implications
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Dynamic determination of the functional state in photolyase and the implication for cryptochrome
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Helix−Coil Kinetics: Folding Time Scales for Helical Peptides from a Sequential Kinetic Model
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Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Development and Applications of Disulfonimides in Enantioselective Organocatalysis
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Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
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Purification and Properties of Human Erythrocyte Carbonic Anhydrases
1966
Toward reliable density functional methods without adjustable parameters: The PBE0 model
1999 Standout
Organic Carbonates
1996 Standout
Carbon capture and conversion using metal–organic frameworks and MOF-based materials
2019 StandoutNobel
An Electronic Mechanism for the Catalysis of Carbonic Anhydrasea
1984
Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin
2002 Nobel
Converting Carbon Dioxide into Carbamato Derivatives
2003
Crystal structure of human carbonic anhydrase II at 1.95 Å resolution in complex with 667-coumate, a novel anti-cancer agent
2005
MULTIPLE MOLECULAR FORMS OF CARBONIC ANHYDRASE IN ERYTHROCYTES*
1968
A simple method for displaying the hydropathic character of a protein
1982 Standout
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
2010 Standout
Simulations of the Large Kinetic Isotope Effect and the Temperature Dependence of the Hydrogen Atom Transfer in Lipoxygenase
2004 StandoutNobel
Crystal Structure of Human Carbonic Anhydrase C
1972
How Important Are Quantum Mechanical Nuclear Motions in Enzyme Catalysis?
1996 StandoutNobel
Solvatochromism, thermochromism, piezochromism, halochromism, and chiro-solvatochromism of pyridinium N-phenoxide betaine dyes
1992
Enzymatic construction of highly strained carbocycles
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The inhibition of human carbonic anhydrase II by some organic compounds
1985
Dynamics of Water in Biological Recognition
2004 Nobel
The Carboxymethylation of Human Carbonic Anhydrase B
1969
Phenol, a competitive inhibitor of CO2 hydration catalyzed by carbonic anhydrase
1982
Facilitated Proton Transfer in Enzyme Catalysis
1968 Science
Monte Carlo simulations of proton pumps: On the working principles of the biological valve that controls proton pumping in cytochrome c oxidase
2006 StandoutNobel
Infrared Studies on the Mechanism of Action of Carbonic Anhydrase
1968
Purification and Properties of Horse Erythrocyte Carbonic Anhydrases
1968
The role of metal ions in the mechanism of action of hydrolytic metalloenzymes: Carbonic anhydrase
1976
The catalytic mechanism of carbonic anhydrase: implications of a rate-limiting protolysis of water
1988
Carbon dioxide hydration activity of carbonic anhydrase in mixtures of water and deuterium oxide
1980
Formation of Stable Carbocations or Zwitterions by a Specific Interaction with Alkali Metal or Alkaline-Earth Metal Ions in Acetonitrile
1998
Carbonic anhydrase inhibitors - Part 49: Synthesis of substituted ureido and thioureido derivatives of aromatic/heterocyclic sulfonamides with increased affinities for isozyme I
1998
Esterase Activities of Human Carbonic Anhydrases B and C
1967 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
DNA-Based Asymmetric Catalysis: Sequence-Dependent Rate Acceleration and Enantioselectivity
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Mechanism of Action of Carbonic Anhydrase
1967
Organocatalytic Asymmetric Transferhydrogenation of β-Nitroacrylates: Accessing β2-Amino Acids
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Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification.
1983
Role of triple ion formation in the acid–base reaction between tropolone and triethylamine in acetonitrile
1994
Carbonic anhydrase inhibitors — Part 53. Synthesis of substituted-pyridinium derivatives of aromatic sulfonamides: The first non-polymeric membrane-impermeable inhibitors with selectivity for isozyme IV
1998
De Novo Computational Design of Retro-Aldol Enzymes
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De Novo Asymmetric Bio- and Chemocatalytic Synthesis of Saccharides − Stereoselective Formal O-Glycoside Bond Formation Using Palladium Catalysis
2003 StandoutNobel
Simulation of enzyme reactions using valence bond force fields and other hybrid quantum/classical approaches
1993 StandoutNobel
Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
2008
Crystallographic studies of azide binding to human carbonic anhydrase II
1993
Kinetics and Mechanism of Carbonic Anhydrase Isoenzymesa
1984
Converting Carbon Dioxide into Carbamato Derivatives
2003
Inhibition and Chemical Modifications of Human Erythrocyte Carbonic Anhydrase B
1967
The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis
1969 Standout
CARBONIC ANHYDRASE: THEORETICAL STUDIES OF DIFFERENT HYPOTHESES
1981
Peptidyl epoxides as selective protease inactivators
2000
Determining complete electron flow in the cofactor photoreduction of oxidized photolyase
2013 StandoutNobel
Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase
2011 StandoutNobel
Carbonic anhydrase inhibitors. Part 37. Novel classes of isozyme I and II inhibitors and their mechanism of action. Kinetic and spectroscopic investigations on native and cobalt-substituted enzymes
1996
Proton Transfer in the Enzyme Carbonic Anhydrase: An ab Initio Study
1998
Carbonic Anhydrase from Parsley Leaves
1970
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II
2007
The Carbon Dioxide Hydration Activity of Carbonic Anhydrase
1971 Standout
Carbonic Anhydrase Inhibitors. Design of Selective, Membrane-Impermeant Inhibitors Targeting the Human Tumor-Associated Isozyme IX
2004
Energy considerations show that low-barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds
1996 StandoutNobel
Results and Problems of O‐Glycoside Synthesis
1974
Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis
1999 Standout
Carbonic anhydrase inhibitors — Part 29 1: Interaction of isozymes I, II and IV with benzolamide-like derivatives
1998
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Y. Pocker being referenced
Ternary complexes of liver alcohol dehydrogenase
2001
Water in enzyme reactions: biophysical aspects of hydration-dehydration processes
2000
Origin of viscosity effects in carbonic anhydrase catalysis. Kinetic studies with bulky buffers at limiting concentrations
1988
Catalytic versatility of erythrocyte carbonic anhydrase. VII. Kinetic studies of esterase activity and competitive inhibition by substrate analogs
1968
Kinetics of inactivation of erythrocyte carbonic anhydrase by sodium 2,6-pyridinedicarboxylate
1980
Epoxides in vicinal diol dehydration. 7. A mechanistic characterization of the spontaneous ring opening process of epoxides in aqueous solution: kinetic and product studies
1988
Oxonase and esterase activities of erythrocyte carbonic anhydrase
1978
Inactivation of bovine carbonic anhydrase by dipicolinate: kinetic studies and mechanistic implications
1983
The bicarbonate proton in carbonic anhydrase catalysis
1983
Electrostatic Modulation by Ionic Aggregates: Charge Transfer Transitions in Solutions of Lithium Perchlorate−Diethyl Ether
2002
Observation of a novel effect on the anionic inhibition of carbonic anhydrase: implications for enzymic catalysis
1981
Kinetics and mechanism of vic-diol dehydration. I. Origin of epoxide intermediates in certain pinacolic rearrangements
1970
Carbonic Anhydrase: Structure, Catalytic Versatility, and Inhibition
1979
The Catalytic Versatility of Erythrocyte Carbonic Anhydrase. I. Kinetic Studies of the Enzyme-Catalyzed Hydration of Acetaldehyde*
1965
Inhibition of Carbonic Anhydrase by Anions in the Carbon Dioxide-Bicarbonate System
1978 Science
The Catalytic Versatility of Carbonic Anhydrase from Erythrocytes. The Enzyme-Catalyzed Hydration of Acetaldehyde
1965
Electrophilic Catalysis in Nucleophilic Substitution and Elimination. III. Conductances of Some Silver and Tetraethylammonium Salts in Acetonitrile and the Kinetics of Reaction of 2-Octyl Bromide with Tetraethylammonium and Silver Nitrates in That Solvent1,2
1965
The Catalytic Versatility of Erythrocyte Carbonic Anhydrase. III. Kinetic Studies of the Enzyme-Catalyzed Hydrolysis of p-Nitrophenyl Acetate*
1967
The dehydration of glyoxalate hydrate: general-acid, general-base, metal ion and enzymic catalysis
1991
Kinetic studies of bovine carbonic anhydrase catalyzed hydrolyses of p-substituted phenyl esters
1972
Zinc-activated alcohols in ternary complexes of liver alcohol dehydrogenase.
1990
Stopped-flow studies of carbon dioxide hydration and bicarbonate dehydration in water and water-d2. Acid-base and metal ion catalysis
1977
Kinetics and mechanism of addition of acids to olefins. IV. Addition of hydrogen and deuterium chloride to 3-methyl-1-butene, 3,3-dimethyl-1-butene, 1-methylcyclopentene, and 1-methylcyclopentene-2,5,5-d3
1969
Electrostatic catalysis by ionic aggregates. 4. Rearrangement of 1-phenylallyl chloride in lithium perchlorate solutions in aprotic solvents
1977
Modulation of Tautomeric Equilibria by Ionic Clusters. Acetylacetone in Solutions of Lithium Perchlorate−Diethyl Ether
2002
Electrostatic catalysis by ionic aggregates. 7. Interactions of dipolar indicator molecules with ionic clusters
1989
Catalytic versatility of erythrocyte carbonic anhydrase. IV. Kinetic studies of enzyme-catalyzed hydrolyses of p-nitrophenyl esters
1968
Effects of pH on anionic inhibition of carbonic anhydrase activities
1982
Electrostatic catalysis by ionic aggregates. 6. Modulation of proton-transfer equilibria by lithium perchlorate-diethyl ether clusters
1988
Enzyme kinetics in solvents of increased viscosity. Dynamics aspects of carbonic anhydrase catalysis
1987
The Catalytic Versatility of Erythrocyte Carbonic Anhydrase. The Enzyme-Catalyzed Hydrolysis of p-Nitrophenyl Acetate
1965
Comparative studies of bovine carbonic anhydrase in H2O and D2O. Stopped-flow studies of the kinetics of interconversion of CO2 and HCO3-
1977
The catalytic versatility of erythrocyte carbonic anhydrase. VI. Kinetic studies of noncompetitive inhibition of enzyme-catalyzed hydrolysis of p-nitrophenyl acetate
1968
Electrostatic catalysis by ionic aggregates. 5. Aminolysis reaction of p-nitrophenyl acetate with imidazole and the proton transfer from p-nitrophenol in lithium perchlorate-diethyl ether solutions
1977
The Catalytic Versatility of Erythrocyte Carbonic Anhydrase. II. Kinetic Studies of the Enzyme-Catalyzed Hydration of Pyridine Aldehydes*
1967
Active‐Site Mechanisms of the Carbonic Anhydrasesa
1984
The inhibition of bovine carbonic anhydrase by saccharin and 2- and 4-carbobenzoxybenzene sulfonamide.
1998
Reversible hydration of pyruvic acid. II. Metal ion and enzymic catalysis
1970
The catalytic versatility of erythrocyte carbonic anhydrase. V. Kinetic studies of enzyme-catalyzed hydrations of aliphatic aldehydes
1968
Catalytic versatility of erythrocyte carbonic anhydrase. VIII. Deuterium solvent isotope effects and apparent activation parameters for the enzyme-catalyzed hydrolysis of p-nitrophenyl acetate
1968
Electrostatic catalysis of ionic aggregates. I. Ionization and dissociation of trityl chloride and hydrogen chloride in lithium perchlorate-diethyl ether solutions
1970
Kinetics and mechanism of addition of acids to olefins. III. Addition of hydrogen chloride to 2-methyl-1-butene, 2-methyl-2-butene, and isoprene in nitromethane
1969