Citation Impact
Citing Papers
Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World
2006 Standout
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
Algorithm 887
2008
Translocations of the RARα gene in acute promyelocytic leukemia
2001
ROS stress in cancer cells and therapeutic implications
2004 Standout
CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing
2011
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
Use of arsenic trioxide (As2O3) in the treatment of patients with acute promyelocytic leukemia
2003 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
1998
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
2008
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide
1998
The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine
2011 Standout
Signal transduction pathways and transcription factors triggered by arsenic trioxide in leukemia cells
2010
Chronic inflammation and oxidative stress in human carcinogenesis
2007
Arsenite Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore
1999
A New Protein Conjugation System in Human
1998 StandoutNobel
Promoting apoptosis as a strategy for cancer drug discovery
2005
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
1998 Standout
Pharmacokinetics, Metabolism, and Carcinogenicity of Arsenic
2001
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)
1999
Effect of arsenic trioxide on viability, proliferation, and apoptosis in human megakaryocytic leukemia cell lines
1999
Role of autophagy in cancer
2007 Standout
Topoisomerase I-DNA Complexes Contribute to Arsenic Trioxide-induced Apoptosis
2004
Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3
2004
The Bcl2 family: regulators of the cellular life-or-death switch
2002 Standout
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia
2000
Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study.
1997
SUMO
2005 Standout
Retinoids in cancer therapy.
1992
Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines
2003
The molecular biology of cancer
2000
Characterization of molecular events in a series of bladder urothelial carcinoma cell lines with progressive resistance to arsenic trioxide
2004
Molecular genetics of acute promyelocytic leukemia
1999
Molecular Heterogeneity of the PML Gene Rearrangement in Acute Promyelocytic Leukemia: Prevalence and Clinical Significance
1993
Pathways of retinoic acid- or arsenic trioxide-induced PML/RARα catabolism, role of oncogene degradation in disease remission
2001
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Polyoxometalate clusters, nanostructures and materials: From self assembly to designer materials and devices
2006 Standout
Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro
1999
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Death and anti-death: tumour resistance to apoptosis
2002 Standout
Head and Neck Cancer
1993 Standout
Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all‐trans retinoic acid
2000
Autophagy in cell death: an innocent convict?
2005 Standout
Acute promyelocytic leukaemia: novel insights into the mechanisms of cure
2010
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
The Nuclear Dot Protein Sp100, Characterization of Domains Necessary for Dimerization, Subcellular Localization, and Modification by Small Ubiquitin-like Modifiers
1999
The BCL-2 protein family: opposing activities that mediate cell death
2007 Standout
Quantitative real-time RT-PCR analysis of PML-RARalpha mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129
2002
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
2012 Standout
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
Arsenic Trioxide: Acute Promyelocytic Leukemia and Beyond
2002
Inhibition of Mitochondrial Respiration
2003
The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects
2002
Association of PML-RAR alpha fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: an intergroup molecular study.
1997
Oxidative stress and apoptosis: a new treatment paradigm in cancer
2006
Revised Recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
2003 Standout
Molecular Targets of Arsenic Trioxide in Malignant Cells
2002
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
2005
United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia
2001 Standout
Combined Arsenic and Retinoic Acid Treatment Enhances Differentiation and Apoptosis in Arsenic-Resistant NB4 Cells
1998
Genetic Diagnosis and Molecular Monitoring in the Management of Acute Promyelocytic Leukemia
1999
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Acute Promyelocytic Leukemia
1993
Arsenic Trioxide and Melarsoprol Induce Programmed Cell Death in Myeloid Leukemia Cell Lines and Function in a PML and PML-RAR Independent Manner
1998
Histone deacetylases (HDACs): characterization of the classical HDAC family
2003 Standout
Trivalent Antimonials Induce Degradation of the PML-RAR Oncoprotein and Reorganization of the Promyelocytic Leukemia Nuclear Bodies in Acute Promyelocytic Leukemia NB4 Cells
1998
Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway.
1999
Early Detection of Relapse by Prospective Reverse Transcriptase-Polymerase Chain Reaction Analysis of the PML/RARα Fusion Gene in Patients With Acute Promyelocytic Leukemia Enrolled in the GIMEMA-AIEOP Multicenter “AIDA” Trial
1998
Cell Apoptosis Induced by Carcinogenic Metals
2001
Interstitial insertion of retinoic acid receptor-alpha gene in acute promyelocytic leukemia with normal chromosomes 15 and 17
1994
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Three-dimensional organization of promyelocytic leukemia nuclear bodies
2010 StandoutNobel
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
2009 Standout
Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis
2001
Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients.
1999
Ascorbic acid enhances arsenic trioxide–induced cytotoxicity in multiple myeloma cells
2001
Acute Myeloid Leukemia and Acute Promyelocytic Leukemia
2003
Malignant Cells Can Be Sensitized to Undergo Growth Inhibition and Apoptosis by Arsenic Trioxide Through Modulation of the Glutathione Redox System
1999
Therapy of Molecular Relapse in Acute Promyelocytic Leukemia
1999
Common Properties of Nuclear Body Protein SP100 and TIF1α Chromatin Factor: Role of SUMO Modification
2001
Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.
2003
Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents
2003
Arsenic Trioxide Selectively Induces Acute Promyelocytic Leukemia Cell Apoptosis Via a Hydrogen Peroxide-Dependent Pathway
1999
Early mortality and the retinoic acid syndrome in acute promyelocytic leukemia: impact of leukocytosis, low-dose chemotherapy, PMN/RAR-alpha isoform, and CD13 expression in patients treated with all-trans retinoic acid
1994
Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins
1999 StandoutNobel
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
2007
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
The Ecology of Arsenic
2003 StandoutScience
Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia
2001 Nobel
Leukocytosis and the Retinoic Acid Syndrome in Patients With Acute Promyelocytic Leukemia Treated With Arsenic Trioxide
2000
Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
2001
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
Inhibition of Macroautophagy Triggers Apoptosis
2005 Standout
Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines.
2000
Protein Modification by SUMO
2004 Standout
The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial
1998 Standout
Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy
1999 StandoutNobel
Prognostic significance of minimal residual disease detection and PML/RAR-α isoform type: long-term follow-up in acute promyelocytic leukemia
2001
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Creatine Kinase Gene Mutation in a Patient with Muscle Creatine Kinase Deficiency
2001 StandoutNobel
Fitting Linear Mixed-Effects Models Usinglme4
2015 Standout
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Cell apoptosis induced by carcinogenic metals
2001
Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia
1999
Mechanisms of action of arsenic trioxide.
2002
Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients
1997 Standout
Works of XS Li being referenced
Studies on the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia: a comparison with conventional dosage
2001
Acute promyelocytic leukemia: clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse
1993
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
1996
Acute promyelocytic leukemia: clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse
1993
Computing Row and Column Counts for Sparse QR and LU Factorization
2001
Rearrangements in the second intron of the RARA gene are present in a large majority of patients with acute promyelocytic leukemia and are used as molecular marker for retinoic acid-induced leukemic cell differentiation
1991
Rearrangements in the second intron of the RARA gene are present in a large majority of patients with acute promyelocytic leukemia and are used as molecular marker for retinoic acid-induced leukemic cell differentiation
1991
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
1996