Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease
2019
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Polycystin-1 Activates and Stabilizes the Polycystin-2 Channel
2003
The trp ion channel family
2001
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Permeation and Gating Properties of the Novel Epithelial Ca2+ Channel
2000
Polycystins: polymodal receptor/ion-channel cellular sensors
2005
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
2000
Polycystin‐2 associates with the polycystin‐1 homolog, suREJ3, and localizes to the acrosomal region of sea urchin spermatozoa
2004
Cation–π interactions in ligand recognition and catalysis
2002
Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein
2014 Standout
Subcellular localization and trafficking of polycystins
2005
The diversity in the vanilloid (TRPV) receptor family of ion channels
2002
TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression
2004
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Localization and Regulation of the Epithelial Ca2+ Channel TRPV6 in the Kidney
2003
From worm to man: three subfamilies of TRP channels
2000
Probing cellular protein complexes using single-molecule pull-down
2011 Nature
TRP channels and lipids: from Drosophila to mammalian physiology
2006
Physiology of Cell Volume Regulation in Vertebrates
2009
Expression of CaT-like, a Novel Calcium-selective Channel, Correlates with the Malignancy of Prostate Cancer
2001
2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3
2004
The Recombinant Human TRPV6 Channel Functions as Ca2+Sensor in Human Embryonic Kidney and Rat Basophilic Leukemia Cells
2002
Calcium Absorption Across Epithelia
2004
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Polycystin-1 and -2 Dosage Regulates Pressure Sensing
2009
The A563T variation of the renal epithelial calcium channel TRPV5 among African Americans enhances calcium influx
2009
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
2003 Standout
Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2
2018
Insights into the molecular nature of magnesium homeostasis
2004
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Store-Operated Calcium Channels
2005 Standout
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Identification and characterization of the single channel function of human mucolipin‐1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway
2002
(Patho)physiological implications of the novel epithelial Ca2+ channels TRPV5 and TRPV6
2003
Structural Conservation of the Genes Encoding CaT1, CaT2, and Related Cation Channels
2001
Permeation through store-operated CRAC channels in divalent-free solution: potential problems and implications for putative CRAC channel genes
2002
The Position of the Polycystic Kidney Disease 1 (PKD1) Gene Mutation Correlates with the Severity of Renal Disease
2002
Age-dependent alterations in Ca2+homeostasis: role of TRPV5 and TRPV6
2006
Functional links between mucolipin-1 and Ca2+-dependent membrane trafficking in mucolipidosis IV
2004
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Role of polycystins in renal tubulogenesis
2003
Transport Function of the Naturally Occurring Pathogenic Polycystin-2 Mutant, R742X
2001
Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily
2005
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
CaT1 Expression Correlates with Tumor Grade in Prostate Cancer
2001
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Constitutive Activation of G-proteins by Polycystin-1 Is Antagonized by Polycystin-2
2002
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Calcium-Selective Ion Channel, CaT1, Is Apically Localized in Gastrointestinal Tract Epithelia and Is Aberrantly Expressed in Human Malignancies
2002
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
A tale of two tails: ciliary mechanotransduction in ADPKD
2003
Polycystin 2 Interacts with Type I Inositol 1,4,5-Trisphosphate Receptor to Modulate Intracellular Ca2+ Signaling
2005
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Polycystin-2 is an intracellular calcium release channel
2002
Store Depletion-activated CaT1 Currents in Rat Basophilic Leukemia Mast Cells Are Inhibited by 2-Aminoethoxydiphenyl Borate
2002
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Epithelial Ca2+ and Mg2+ Channels in Health and Disease
2004
The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation
2003
The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway
2001
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Opening of the human epithelial calcium channel TRPV6
2017 Nature
Hepatic expression and cellular distribution of the glucose transporter family
2012
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6
2003
Molecular Architecture and Subunit Organization of TRPA1 Ion Channel Revealed by Electron Microscopy
2011
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
2003
Polycystins, calcium signaling, and human diseases
2004
Structural and Functional Similarities of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel with Connexins, Pannexins, and Innexins*
2013
Cellular and molecular function of mucolipins (TRPML) and polycystin 2 (TRPP2)
2005
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Whole‐cell and single channel monovalent cation currents through the novel rabbit epithelial Ca2+ channel ECaC
2000
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
2004
Function and expression of the epithelial Ca2+ channel family: comparison of mammalian ECaC1 and 2
2001
Epithelial calcium channel: gate-keeper of active calcium reabsorption
2000
Transient Receptor Potential Cation Channels in Disease
2007 Standout
CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties
2001
CaT1 Contributes to the Stores-operated Calcium Current in Jurkat T-lymphocytes
2002
TRPV6 potentiates calcium-dependent cell proliferation
2005
Warm Temperatures Activate TRPV4 in Mouse 308 Keratinocytes
2003
TRPV5 and TRPV6 in Ca2+ (re)absorption: regulating Ca2+ entry at the gate
2005
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Polycystin-1 and polycystin-2 regulate the cell cycle through the helix–loop–helix inhibitor Id2
2005
The epithelial calcium channels TRPV5 and TRPV6: regulation and implications for disease
2005
Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2+
2001
Extended Life-Span Conferred by Cotransporter Gene Mutations in Drosophila
2000 Science
Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.
1982 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
TRP Channel Proteins and Signal Transduction
2002
The ion selectivity filter is not an activation gate in TRPV1-3 channels
2019
Structure-based characterization of novel TRPV5 inhibitors
2019
Molecular mechanism of TRPV2 channel modulation by cannabidiol
2019
CaT1 manifests the pore properties of the calcium-release-activated calcium channel
2001 Nature
PERMEATION AND SELECTIVITY OF TRP CHANNELS
2005
Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy
2002
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Transient Receptor Potential Channels in Cardiovascular Function and Disease
2006
The TRP Superfamily of Cation Channels
2005
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif
2006
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
2003
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I
2001 StandoutNobel
TRPV4 calcium entry channel: a paradigm for gating diversity
2004
PKD2 Functions as an Epidermal Growth Factor-Activated Plasma Membrane Channel
2005
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4
2009 StandoutNobel
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
Gating of the polycystin ion channel signaling complex in neurons and kidney cells
2004
Ion channels in synaptic vesicles from Torpedo electric organ.
1988 StandoutNobel
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Molecular Mechanism of Active Ca2+ Reabsorption in the Distal Nephron
2002
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents
1986 StandoutNobel
Capacitative calcium entry in the nervous system
2003
Capsaicin Inhibits Jurkat T-Cell Activation by Blocking Calcium Entry Current ICRAC
2001
Voltage dependence of K + channels in guard-cell protoplasts
1987 StandoutNobel
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Polycystin channels and kidney disease
2001
Native Polycystin 2 Functions as a Plasma Membrane Ca2+-Permeable Cation Channel in Renal Epithelia
2003
TRP Channels
2007 Standout
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Vanilloid and TRP channels: a family of lipid-gated cation channels
2002
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting
2013
The epithelial Ca 2+ channel TRPV5 is essential for proper osteoclastic bone resorption
2005
Evidence that Ca2+-release-activated Ca2+ channels in rat hepatocytes are required for the maintenance of hormone-induced Ca2+ oscillations
2003
Intestinal absorption of water-soluble vitamins in health and disease
2011
Works of Xing‐Zhen Chen being referenced
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
2018
Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation
2016
Alpha-actinin associates with polycystin-2 and regulates its channel activity
2005
Permeation and inhibition of polycystin-l channel by monovalent organic cations
2006
The calcium‐binding EF‐hand in polycystin‐L is not a domain for channel activation and ensuing inactivation
2002
Characterization of a Rat Na+-Dicarboxylate Cotransporter
1998
Effect of hydro-osmotic pressure on polycystin-2 channel function in the human syncytiotrophoblast
2005
Yeast SMF1 Mediates H+-coupled Iron Uptake with Concomitant Uncoupled Cation Currents
1999
Polycystin-2 Is a Novel Cation Channel Implicated in Defective Intracellular Ca2+ Homeostasis in Polycystic Kidney Disease
2001
Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption
1999
Receptor for Activated C Kinase 1 (RACK1) Inhibits Function of Transient Receptor Potential (TRP)-type Channel Pkd2L1 through Physical Interaction
2011
Modulation of the human polycystin‐L channel by voltage and divalent cations
2002
The S4–S5 linker – gearbox of TRP channel gating
2017
Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton
2008
Functional Roles of Histidine and Tyrosine Residues in the H+-Peptide Transporter PepT1
2000
Identification and characterization of hydrophobic gate residues in TRP channels
2017
1999 Nature
Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine
2004
Troponin I Binds Polycystin-l and Inhibits Its Calcium-Induced Channel Activation
2003
Polycystin-2 Interacts with Troponin I, an Angiogenesis Inhibitor
2002
Structural and molecular basis of the assembly of the TRPP2/PKD1 complex
2009
Far Upstream Element-Binding Protein 1 Binds the 3′ Untranslated Region of PKD2 and Suppresses Its Translation
2016
A family of mammalian Na+-dependent L-ascorbic acid transporters
1999 Nature