Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
2013
Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
2013
CRISPR/Cas9 in Genome Editing and Beyond
2016
Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance
2014 StandoutNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Precision cancer mouse models through genome editing with CRISPR-Cas9
2015
Differential expression analysis for sequence count data
2010 Standout
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
2010
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
TCC: an R package for comparing tag count data with robust normalization strategies
2013
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
2014 Standout
Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex
2014
Catalytically Active Cas9 Mediates Transcriptional Interference to Facilitate Bacterial Virulence
2019 StandoutNobel
Differential analysis of gene regulation at transcript resolution with RNA-seq
2012 Standout
Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference
2015
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
2012 Standout
Editing the epigenome: technologies for programmable transcription and epigenetic modulation
2016
Pro-senescence therapy for cancer treatment
2011
Geriatric muscle stem cells switch reversible quiescence into senescence
2014 Nature
The genomic landscape of Neanderthal ancestry in present-day humans
2014 StandoutNatureNobel
Expanding the CRISPR imaging toolset withStaphylococcus aureusCas9 for simultaneous imaging of multiple genomic loci
2016
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
sgRNAcas9: A Software Package for Designing CRISPR sgRNA and Evaluating Potential Off-Target Cleavage Sites
2014
Exploiting CRISPR–Cas immune systems for genome editing in bacteria
2015
A decade of discovery: CRISPR functions and applications
2017
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation
2015
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
The essence of senescence: Figure 1.
2010 Standout
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells
2015
High-throughput functional genomics using CRISPR–Cas9
2015
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Cellular senescence and its effector programs
2014
The next generation of CRISPR–Cas technologies and applications
2019
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
2013 Nobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
2012
From RNA-seq reads to differential expression results
2010
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Evaluation of sgRNA Target Sites for CRISPR-Mediated Repression of TP53
2014
Cell fusion induced by ERVWE1 or measles virus causes cellular senescence
2013
Cellular senescence: from physiology to pathology
2014 Standout
CRISPR/Cas9-Mediated Genome Editing of Epigenetic Factors for Cancer Therapy
2015
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Aging, Cellular Senescence, and Cancer
2012 Standout
A powerful and flexible approach to the analysis of RNA sequence count data
2011
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
CRISPR-Cas9 nuclear dynamics and target recognition in living cells
2016
Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals
2016 StandoutScienceNobel
CRISPR-Cas: biology, mechanisms and relevance
2016 StandoutNobel
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Computational methods for transcriptome annotation and quantification using RNA-seq
2011
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
GFOLD: a generalized fold change for ranking differentially expressed genes from RNA-seq data
2012
Finding consistent patterns: A nonparametric approach for identifying differential expression in RNA-Seq data
2011
Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview
2019
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Design and Analysis of Bar-seq Experiments
2013
PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures
2018
Target specificity of the CRISPR‐Cas9 system
2014
A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data
2012
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
MicroRNA-128 Governs Neuronal Excitability and Motor Behavior in Mice
2013 Science
Jumonji C Demethylases in Cellular Senescence
2019
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Xiaowo Wang being referenced
CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation: Fig. 1.
2015
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
2013
Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence
2010
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
2012
Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity
2011
Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain
2012
The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence
2012
DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
2009 Standout
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
2012