Citation Impact
Citing Papers
Phase II Trial of Sorafenib in Advanced Thyroid Cancer
2008
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
TOR Signaling in Growth and Metabolism
2006 Standout
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
EGFR Antagonists in Cancer Treatment
2008 Standout
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
Inflammation and cancer
2002 StandoutNature
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis
2005 StandoutNobel
Inflammation and metabolic disorders
2006 StandoutNature
E2Fs Regulate Adipocyte Differentiation
2002
PPARγ: a Nuclear Regulator of Metabolism, Differentiation, and Cell Growth
2001
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Hic-5 regulates an epithelial program mediated by PPARγ
2005
Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung Cancer
2003 Standout
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Reduced Expression of PTEN Protein and Its Prognostic Implications in Invasive Ductal Carcinoma of the Breast
2005
Endometriosis
2009 Standout
The human homologue of unc-93 maps to chromosome 6q27 – characterisation and analysis in sporadic epithelial ovarian cancer
2002
Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner
2011
Tenets of PTEN Tumor Suppression
2008
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network
2008 Nature
From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family
2003
Activation of AKT Kinases in Cancer: Implications for Therapeutic Targeting
2005
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
2003 Standout
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
PTEN: One Gene, Many Syndromes
2003
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 ( SMAD4)
2004 Standout
Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis
2008 Standout
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
2010 Standout
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
2011
The Akt-mTOR tango and its relevance to cancer
2005
Colorectal cancer
2019 Standout
Molecular Classification of Patients With Unexplained Hamartomatous and Hyperplastic Polyposis
2005
The role of PTEN signaling perturbations in cancer and in targeted therapy
2008
PTEN expression in non–small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration
2005
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
2006
Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression
2007
Graves' Ophthalmopathy
2010 Standout
Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN
2001
Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy
2009
Increased activated Akt expression in renal cell carcinomas and prognosis
2008
αv integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells
2003
Malignant Gliomas in Adults
2008 Standout
Carotenoids and transcription
2004
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Genetic basis of Cowden syndrome and its implications for clinical practice and risk management
2016
Endometriosis
2010 Standout
TGFβ in Cancer
2008 Standout
Inflammation and the development of pancreatic cancer
2002
The search for genes contributing to endometriosis risk
2008
Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
2010
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The functions and regulation of the PTEN tumour suppressor
2012 Standout
Idiopathic pulmonary fibrosis
2011 Standout
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
The PI3K Pathway in Human Disease
2017 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
2010 Standout
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer
2006
Motesanib Diphosphate in Progressive Differentiated Thyroid Cancer
2008
Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
2010 StandoutScience
PTEN Modulates Vascular Endothelial Growth Factor-Mediated Signaling and Angiogenic Effects
2002
Genetic Causes of Brain Tumors: Neurofibromatosis, Tuberous Sclerosis, von Hippel-Lindau, and Other Syndromes
2007
ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes
2015
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
2009
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.
2002
Oxidative Dehydrogenation of Ethane to Ethene over BaO- and BaBr2-Modified Ho2O3Catalysts
1998
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
2008
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
2001
APC-dependent suppression of colon carcinogenesis by PPARγ
2002
The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway
2004
Emerging Insights into the Molecular Pathogenesis of Uveal Melanoma
2008
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
PTENGene Targeting Reveals a Radiation-Induced Size Checkpoint in Human Cancer Cells
2004
Peroxisome Proliferator-Activated Receptor-γ Calls for Activation in Moderation: Lessons from Genetics and Pharmacology
2004
PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors
2010
Chemical Structures and Performance of Perovskite Oxides
2001 Standout
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
2007 StandoutNobel
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Molecular and Pathologic Aspects of Endometrial Carcinogenesis
2006
Works of Xiao-Ping Zhou being referenced
Frequent Loss of PTEN Expression Is Linked to Elevated Phosphorylated Akt Levels, but Not Associated with p27 and Cyclin D1 Expression, in Primary Epithelial Ovarian Carcinomas
2001
Gi Polyposis and Glycogenic Acanthosis of The Esophagus Associated With Pten Mutation Positive Cowden Syndrome in The Absence of Cutaneous Manifestations
2003
Mutation-Positive and Mutation-Negative Patients with Cowden and Bannayan-Riley-Ruvalcaba Syndromes Associated with Distinct 10q Haplotypes
2006
Distinct Expression Profiles for PTEN Transcript and Its Splice Variants in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome
2006
PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers
2002
Germline PTEN Promoter Mutations and Deletions in Cowden/Bannayan-Riley-Ruvalcaba Syndrome Result in Aberrant PTEN Protein and Dysregulation of the Phosphoinositol-3-Kinase/Akt Pathway
2003
Germline Inactivation of PTEN and Dysregulation of the Phosphoinositol-3-Kinase/Akt Pathway Cause Human Lhermitte-Duclos Disease in Adults
2003
High Frequency of Submicroscopic Hemizygous Deletion Is a Major Mechanism of Loss of Expression ofPTENin Uveal Melanoma
2005
Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer
2000
Biallelic inactivating mutations and an occult germline mutation ofPTEN in primary cervical carcinomas
2000
EPR characterization of O? and trapped electrons in 20% SrF2/SmOF
1996
Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial carcinoma cases and underrepresentation of P12A in renal cell carcinoma cases
2001