Citation Impact
Citing Papers
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
2004 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
Morphology of sporadic colorectal cancer with DNA replication errors
1998
Hallmarks of Cancer: The Next Generation
2011 Standout
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
HIF‐1α and HIF‐2α have divergent roles in colon cancer
2008
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis
2012
Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
2000
BRAF alterations are associated with complex mutational profiles in malignant melanoma
2004
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Inflammation and metabolic disorders
2006 StandoutNature
Analysis of the genome to personalize therapy for melanoma
2010
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
2002 StandoutNature
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
Innate and adaptive immune cells in the tumor microenvironment
2013 Standout
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
1998
Reduced Expression of PTEN Protein and Its Prognostic Implications in Invasive Ductal Carcinoma of the Breast
2005
<i>p53</i> Gene Mutation, Microsatellite Instability and Adjuvant Chemotherapy: Impact on Survival of 388 Patients with Dukes’ C Colon Carcinoma
2000
Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function
2001 StandoutNobel
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Tenets of PTEN Tumor Suppression
2008
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network
2008 Nature
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
PTEN: One Gene, Many Syndromes
2003
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
1999
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
2001 StandoutNobel
Genetic Interaction Between NRAS and BRAF Mutations and PTEN/MMAC1 Inactivation in Melanoma
2004
PTEN: Life as a Tumor Suppressor
2001
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Hereditary Colorectal Cancer
2003 Standout
Inactivation of PKCθ leads to increased susceptibility to obesity and dietary insulin resistance in mice
2006
Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β2‐microglobulin inactivation in MSI‐positive tumors and LMP7/TAP2 downregulation in MSI‐negative tumors
2003
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers
2001
Mutations of the human PTEN gene
2000
Determination of microsatellite instability,p53 and K-RAS mutations in hepatic metastases from patients with colorectal cancer: Relationship with response to 5-fluorouracil and survival
2001
Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status
2000
Primary brain tumours in adults
2003
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Primary brain tumours in adults
2012 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Glioblastomas with an Oligodendroglial Component: A Pathological and Molecular Study
2001
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Transgenic mice with dominant negative PKC‐theta in skeletal muscle: A new model of insulin resistance and obesity
2003
PTEN function in mammalian cell size regulation
2002
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
Signaling pathways in insulin action: molecular targets of insulin resistance
2000
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
2004
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Testing tumors for microsatellite instability
1999
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Cancer-related inflammation
2008 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
PKC-θ knockout mice are protected from fat-induced insulin resistance
2004
External Regulation of Controlled Polymerizations
2012
IL-10 deficiency leads to somatic mutations in a model of IBD
2006
Molecular Epidemiology of Primary Brain Tumors
2009
ASCO 2006 Update of Recommendations for the Use of Tumor Markers in Gastrointestinal Cancer
2006
Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors
2002
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
2007
Sodium Channels in Normal and Pathological Pain
2010
Wnt signaling and cancer
2000 Standout
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
2008
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
2009
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Malonyl-CoA, fuel sensing, and insulin resistance
1999
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability.
2003
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells.
2003
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.
1998
Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression
2001
Myofibroblasts. II. Intestinal subepithelial myofibroblasts
1999
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Nanostraw–Electroporation System for Highly Efficient Intracellular Delivery and Transfection
2013
Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
2005
Neoantigens in cancer immunotherapy
2015 StandoutScience
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.
1998 Standout
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis
2008
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?
2011
Population-Based Molecular Detection of Hereditary Nonpolyposis Colorectal Cancer
2000
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice.
2000 StandoutNobel
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Xiaoping Zhou being referenced
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
2001
Mutation of the transforming growth factor-β type II receptor gene in right-sided colorectal cancer: relationship to clinicopathological features and genetic alterations
1998
Small interfering RNA-mediated selective knockdown of NaV1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats
2007
A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms
1997
Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites
1998
Epigenetic PTEN Silencing in Malignant Melanomas without PTEN Mutation
2000
Allelic profiles of mononucleotide repeat microsatellites in control individuals and in colorectal tumors with and without replication errors
1997
Germline mutations ofp53 but notp16/CDKN2 orPTEN/MMAC1 tumor suppressor genes predispose to gliomas
1999
Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis
2000
Mutational analysis of the PTEN gene in gliomas: Molecular and pathological correlations
1999
Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability.
1999
5‐Chloro‐7‐iodo‐8‐quinolinolatomanganese(III) with the Feature of pH‐Regulated Molecular Switches as a Highly Efficient Catalyst for Epoxidation of Olefins with Hydrogen Peroxide
2008
Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis
1996