Citation Impact
Citing Papers
The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation
2002 StandoutScienceNobel
CTLA-4-Mediated Inhibition of Early Events of T Cell Proliferation
1999 StandoutNobel
The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival
1998
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
1997 StandoutNature
Activation of the Hematopoietic Progenitor Kinase-1 (HPK1)-dependent, Stress-activated c-Jun N-terminal Kinase (JNK) Pathway by Transforming Growth Factor β (TGF-β)-activated Kinase (TAK1), a Kinase Mediator of TGF β Signal Transduction
1997
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
2005 Standout
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway
1997
Direct Activation of the Stress-activated Protein Kinase (SAPK) and Extracellular Signal-regulated Protein Kinase (ERK) Pathways by an Inducible Mitogen-activated Protein Kinase/ERK Kinase Kinase 3 (MEKK) Derivative
1997
The Role of c-Jun N-terminal Kinase (JNK) in Apoptosis Induced by Ultraviolet C and γ Radiation
1996
MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?
1997
Apoptosis by Death Factor
1997 Standout
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
The Rel Protein DIF Mediates the Antifungal but Not the Antibacterial Host Defense in Drosophila
2000 StandoutNobel
β2-Adrenergic Receptor-induced p38 MAPK Activation Is Mediated by Protein Kinase A Rather than by Gi or Gβγ in Adult Mouse Cardiomyocytes
2000 StandoutNobel
Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro
1997 StandoutNobel
The combination of silencing BAG3 and inhibition of the JNK pathway enhances hyperthermia sensitivity in human oral squamous cell carcinoma cells
2013
Enhancement of p38 Mitogen-activated Protein Kinase Activity by Phosphorylated Glia Maturation Factor
1996
Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb
2000
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Signal transduction through NF-κB
1998
Cellular response to oxidative stress: Signaling for suicide and survival*
2002 Standout
Ectopic Expression of Nonliganded Retinoic Acid Receptor β Abrogates AP-1 Activity by Selective Degradation of c-Jun in Cervical Carcinoma Cells
2004 StandoutNobel
Missing Pieces in the NF-κB Puzzle
2002 Standout
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor
2011 StandoutNobel
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
2001 StandoutNature
Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase
2000 StandoutNobel
Tumor necrosis factor alpha -induced activation of c-jun N-terminal kinase is mediated by TRAF2
1997
The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation
1997 Standout
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA
2004 StandoutNobel
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)
1999
Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain
2000 Standout
Functional Interactions of Transforming Growth Factor β-activated Kinase 1 with IκB Kinases to Stimulate NF-κB Activation
1999
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
1999 StandoutNature
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
Curcumin: From ancient medicine to current clinical trials
2008 Standout
The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor
1998 StandoutNobel
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Redox Regulation of NF-κB Activation: Distinct Redox Regulation Between the Cytoplasm and the Nucleus
2005
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.
1996
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins.
1997
TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor
1997 StandoutNobel
TGF-β SIGNAL TRANSDUCTION
1998 Standout
Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB and Steroid Receptor-Signaling Pathways
1999
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
MEK kinase 1 gene disruption alters cell migration and c-Jun NH 2 -terminal kinase regulation but does not cause a measurable defect in NF-κB activation
2000
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
2001 Standout
Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells
2016
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
1998 StandoutScience
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Death Receptors: Signaling and Modulation
1998 StandoutScience
Lineage-Restricted Function of Nuclear Factor κB–Inducing Kinase (Nik) in Transducing Signals via Cd40
2000 StandoutNobel
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
CD28 Mediates Transcriptional Upregulation of the Interleukin-2 (IL-2) Promoter through a Composite Element Containing the CD28RE and NF-IL-2B AP-1 Sites
1997
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
1998 Standout
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
JNK or IKK, AP-1 or NF-κB, which are the targets for MEK kinase 1 action?
1998
CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy
2001 StandoutNobel
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
2000
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways
1999
Works of Xiaoping Wang being referenced
The JNK inhibitor SP600125 enhances dihydroartemisinin‐induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells
2010
Interaction between c-Rel and the Mitogen-activated Protein Kinase Kinase Kinase 1 Signaling Cascade in Mediating B Enhancer Activation
1996
Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3
2013