Standout Papers
Citation Impact
Citing Papers
Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
2010
Genomic Analysis of a Spontaneous Model of Breast Cancer Metastasis to Bone Reveals a Role for the Extracellular Matrix
2005
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Nuclear factor-κB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells
2010
Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton
2008
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
First-in-Human Pharmacokinetic and Pharmacodynamic Study of the Dual m-TORC 1/2 Inhibitor AZD2014
2015
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
2008 StandoutScience
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
2008
Treatment of kidney cancer
2009 StandoutNobel
Triple-Negative Breast Cancer
2010 Standout
Endogenous human microRNAs that suppress breast cancer metastasis
2008 StandoutNature
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan
2022
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
mTOR Signaling in Growth Control and Disease
2012 Standout
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
Breast cancer
2016 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Targeting hypoxia cell signaling for cancer therapy
2007
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers
2012
Rapid apoptosis in the pulmonary vasculature distinguishes non-metastatic from metastatic melanoma cells
2004
Cancer Metastasis: Building a Framework
2006 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
2010 Standout
Podocalyxin variants and risk of prostate cancer and tumor aggressiveness
2006
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Linking L1CAM-mediated signaling to NF-κB activation
2010
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Isolation of rare circulating tumour cells in cancer patients by microchip technology
2007 StandoutNature
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
2014 StandoutNature
Genetic determinants of cancer metastasis
2007
Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
2009
Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling
2011
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Malignant Gliomas in Adults
2008 Standout
Emerging Biological Principles of Metastasis
2017 Standout
Inhibiting kinases in malignant gliomas
2007
Development of HIF‐1 inhibitors for cancer therapy
2009
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
Methods in Mammalian Autophagy Research
2010 Standout
TGFβ in Cancer
2008 Standout
Molecular Basis of Metastasis
2008
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
2017 Standout
Defining the Role of mTOR in Cancer
2007 Standout
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2
2014
The functions and regulation of the PTEN tumour suppressor
2012 Standout
The PI3K Pathway in Human Disease
2017 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
A Hypoxia-Controlled Cap-Dependent to Cap-Independent Translation Switch in Breast Cancer
2007
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells
2013
An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells
2011
The Type 1 Insulin-Like Growth Factor Receptor Pathway
2008
The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
2011 Science
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Moesin orchestrates cortical polarity of melanoma tumour cells to initiate 3D invasion
2009
Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin
2008
Recent Advances in Polyoxometalate-Catalyzed Reactions
2015 Standout
Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors
2011
Context-Specific Function of S6K2 in Th Cell Differentiation
2016
Oxidation of adamantane with 1 atm molecular oxygen by vanadium-substituted polyoxometalates
2005
CXCR4 Regulates Growth of Both Primary and Metastatic Breast Cancer
2004
The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression
2013
Podocalyxin Increases the Aggressive Phenotype of Breast and Prostate Cancer Cells In vitro through Its Interaction with Ezrin
2007
A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma
2016
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Polymer-supported Schiff base complexes in oxidation reactions
2009
Phase I Dose Escalation Study of the Anti–Insulin-Like Growth Factor-I Receptor Monoclonal Antibody CP-751,871 in Patients with Refractory Solid Tumors
2007
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The Catalytic Valorization of Lignin for the Production of Renewable Chemicals
2010 Standout
Works of Xiaolin Wan being referenced
Phosphoprotein Pathway Mapping: Akt/Mammalian Target of Rapamycin Activation Is Negatively Associated with Childhood Rhabdomyosarcoma Survival
2007
CCI-779 Inhibits Rhabdomyosarcoma Xenograft Growth by an Antiangiogenic Mechanism Linked to the Targeting of mTOR/Hif-1α/VEGF Signaling
2006
Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism
2006
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
2004 Standout
Identification of FoxM1/Bub1b Signaling Pathway as a Required Component for Growth and Survival of Rhabdomyosarcoma
2012
Effect of Insulin-Like Growth Factor II on Protecting Myoblast Cells Against Cisplatin-Induced Apoptosis Through p70 S6 Kinase Pathway
2002
Synthetic retinoid CD437 induces apoptosis of esophageal squamous HET-1A cells through the caspase-3-dependent pathway.
2001
Rapamycin Inhibits Ezrin-Mediated Metastatic Behavior in a Murine Model of Osteosarcoma
2005