Citation Impact
Citing Papers
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH
2012
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
Hepatic fibrosis 2006: Report of the third AASLD Single Topic Conference
2006
PTPN22: the archetypal non-HLA autoimmunity gene
2014
Psoriasis
2009 Standout
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
A Large-Scale Rheumatoid Arthritis Genetic Study Identifies Association at Chromosome 9q33.2
2008
Pathogenesis and clinical features of psoriasis
2007 Standout
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Autoinflammatory Disease Reloaded: A Clinical Perspective
2010 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
2008 Standout
Accelerated Recruitment of New Brain Development Genes into the Human Genome
2011
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
2016 Standout
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
2009 Standout
Host Genetic Factors and Antiviral Immune Responses to Hepatitis C Virus
2008
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
2008 Standout
Development, cytokine profile and function of human interleukin 17–producing helper T cells
2007 Standout
N-myc Downstream-regulated Gene 2, a Novel Estrogen-targeted Gene, Is Involved in the Regulation of Na+/K+-ATPase
2011
Psoriasis
2021 Standout
Inflammatory Bowel Disease
2009 Standout
A general framework for estimating the relative pathogenicity of human genetic variants
2014 Standout
Protein tyrosine phosphatases: from genes, to function, to disease
2006
Complement: a key system for immune surveillance and homeostasis
2010 Standout
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Psoriasis
2015 Standout
A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C†
2007
Functional evaluation of autism-associated mutations in NHE9
2013
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Non-alcoholic fatty liver disease
2021 Standout
Evolving challenges in hepatic fibrosis
2010
A new multipoint method for genome-wide association studies by imputation of genotypes
2007 Standout
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Genome-wide inference of natural selection on human transcription factor binding sites
2013
Polymorphisms in the PTPN22 region are associated with psoriasis of early onset
2008
Type 1 diabetes
2013 Standout
Translating Neurogenomics Into New Medicines
2015
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
2008 Standout
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
2016 StandoutNobel
A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes
2007
Pioneer factors: directing transcriptional regulators within the chromatin environment
2011
Efficiency and power in genetic association studies
2005
Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment
2011
The pancreatic stellate cell: a star on the rise in pancreatic diseases
2007
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
2006
Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis
2007
Relationship between serum urate concentration and clinically evident incident gout: an individual participant data analysis
2018
The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
2012 Standout
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Genetics of Alzheimer’s Disease
2014
A model-based approach to capture genetic variation for future association studies
2006
Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies
2014
PTPN22: Setting thresholds for autoimmunity
2006
COP1 is a tumour suppressor that causes degradation of ETS transcription factors
2011 Nature
The Human Condition—A Molecular Approach
2014 StandoutNobel
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Approximation to the Distribution of Fitness Effects across Functional Categories in Human Segregating Polymorphisms
2014
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
MicroRNA-Driven Developmental Remodeling in the Brain Distinguishes Humans from Other Primates
2011 StandoutNobel
CADD: predicting the deleteriousness of variants throughout the human genome
2018 Standout
Recent Advances in the Genetics of Autoimmune Disease
2008
Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virus
2014 StandoutNobel
Classic Selective Sweeps Were Rare in Recent Human Evolution
2011 Science
Tyrosine Phosphatase PTPN22: Multifunctional Regulator of Immune Signaling, Development, and Disease
2013
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
2016 StandoutNobel
IL-17 and Th17 Cells
2009 Standout
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Inflammatory Bowel Disease
2010 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
PTPN22 Trp620 Explains the Association of Chromosome 1p13 With Type 1 Diabetes and Shows a Statistical Interaction With HLA Class II Genotypes
2008
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Gout
2021 Standout
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function
2010 StandoutNobel
mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
2015
DEAD-box helicases: the Yin and Yang roles in viral infections
2018
Nonalcoholic Fatty Liver Disease
2015 Standout
Further Evidence of a Primary, Causal Association of the PTPN22 620W Variant With Type 1 Diabetes
2007
Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis
2020 StandoutNobel
Works of Xiaolan Hu being referenced
Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes
2009
Contribution of Common Genetic Variants to Antidepressant Response
2012
Functional Genomics Identifies ABCC3 as a Mediator of Taxane Resistance in HER2-Amplified Breast Cancer
2008
Hyperuricemia and the risk for coronary heart disease morbidity and mortality a systematic review and dose-response meta-analysis
2016
PTPN22 Genetic Variation: Evidence for Multiple Variants Associated with Rheumatoid Arthritis
2005
Evolutionary Processes Acting on Candidate cis-Regulatory Regions in Humans Inferred from Patterns of Polymorphism and Divergence
2009
Identification of Two Gene Variants Associated With Risk of Advanced Fibrosis in Patients With Chronic Hepatitis C
2006
Expression analysis of the NDRG2 gene in mouse embryonic and adult tissues
2006
Selecting Tagging SNPs for Association Studies Using Power Calculations from Genotype Data
2004
Family-Based Genome-Wide Association Scan of Attention-Deficit/Hyperactivity Disorder
2010
Meta-Analysis for Genome-Wide Association Study Identifies Multiple Variants at the BIN1 Locus Associated with Late-Onset Alzheimer's Disease
2011
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population
2006