Citation Impact
Citing Papers
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
N-peptidyl, O-acyl hydroxamates: comparison of the selective inhibition of serine and cysteine proteinases
1996
Structural Analysis of the Active Site of Porcine Pancreatic Elastase Based on the X-ray Crystal Structures of Complexes with Trifluoroacetyl-Dipeptide-Anilide Inhibitors
1995
Understanding organofluorine chemistry. An introduction to the C–F bond
2007 Standout
Assessment of the optimization of affinity and specificity at protein–DNA interfaces
2009 StandoutNobel
Freeze trapping of reaction intermediates
1995 StandoutNobel
The Protein Data Bank
2000 Standout
Anatomy of protein pockets and cavities: Measurement of binding site geometry and implications for ligand design
1998
Three-dimensional Structure of MecI
2003
Testing Electrostatic Complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole
2006
Electrostatic Origin of the Catalytic Power of Enzymes and the Role of Preorganized Active Sites
1998 StandoutNobel
Improving enzymes by using them in organic solvents
2001 StandoutNature
The Geometry of the Ribosomal Polypeptide Exit Tunnel
2006 StandoutNobel
Inhibition of dipeptidyl peptidase IV (DPP IV) by 2-(2-amino-1-fluoro-propylidene)-cyclopentanecarbonitrile, a fluoroolefin containing peptidomimetic
2003
Nickel homeostasis in Escherichia coli– the rcnR‐rcnA efflux pathway and its linkage to NikR function
2006
A Simple Physical Model for the Prediction and Design of Protein–DNA Interactions
2004 StandoutNobel
Prediction of binding constants of protein ligands: A fast method for the prioritization of hits obtained from de novo design or 3D database search programs
1998
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Novel Mechanism of Inhibition of Elastase by β-Lactams Is Defined by Two Inhibitor Crystal Complexes
1999
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
2004 StandoutNature
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Improved Modeling of Side-Chain–Base Interactions and Plasticity in Protein–DNA Interface Design
2012 StandoutNobel
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Geometric analysis and comparison of protein-DNA interfaces: why is there no simple code for recognition? 1 1Edited by R. Ebright
2000
Solvent mobility and the protein 'glass' transition.
2000
Proteins in organic solvents
2001
Locating and characterizing binding sites on proteins
1996
Convergent Mechanisms for Recognition of Divergent Cytokines by the Shared Signaling Receptor gp130
2003 StandoutNobel
Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage
2009 Standout
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
What makes a binding site a binding site?
1995
The Hydrogen Bond in the Solid State
2002 Standout
Temperature Dependence of Protein Dynamics: Computer Simulation Analysis of Neutron Scattering Properties
2002
Nmr in drug discovery
2002 StandoutNobel
X-ray studies on two forms of bovine β-trypsin crystals in neat cyclohexane
1998
Binding Site Detection and Druggability Index from First Principles
2009
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles
2001 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Energetics of the Catalytic Reaction of Ribonuclease A: A Computational Study of Alternative Mechanisms
1998 StandoutNobel
Phenyl−Perfluorophenyl Stacking Interactions: Topochemical [2+2] Photodimerization and Photopolymerization of Olefinic Compounds
1998 StandoutNobel
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
Metalle in der Medizin
1999
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Water as an Active Constituent in Cell Biology
2007 Standout
Orbital Steering in the Catalytic Power of Enzymes: Small Structural Changes with Large Catalytic Consequences
1997 Science
Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization
2010 StandoutNobel
The crystal structure of subtilisin Carlsberg in anhydrous dioxane and its comparison with those in water and acetonitrile
1997
Structural Aspects of Nucleic Acid Analogs and Antisense Oligonucleotides
1996
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy
2004 Standout
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Fragment-guided design of subnanomolar β-lactamase inhibitors active in vivo
2012
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
Protein Pockets: Inventory, Shape, and Comparison
2010
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
2006
Solvent dependence of dynamic transitions in protein solutions
2000
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Stereoselective Cyclopropanation Reactions
2003 Standout
Synthesis, reactions and structural features of monofluorinated cyclopropanecarboxylates
2002
Simulations of RNA base pairs in a nanodroplet reveal solvation-dependent stability
2007 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Structure-Based Approach for Binding Site Identification on AmpC β-Lactamase
2002
Iron Metabolism in Pathogenic Bacteria
2000
What Can We Learn from Molecular Recognition in Protein–Ligand Complexes for the Design of New Drugs?
1996
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Role of organic fluorine in crystal engineering
2011
Crystal structure of triosephosphate isomerase from Trypanosoma cruzi in hexane
1999
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Organic Fluorine Hardly Ever Accepts Hydrogen Bonds
1997
The Halogen Bond
2016 Standout
Discovering High-Affinity Ligands for Proteins: SAR by NMR
1996 StandoutScience
NMR Assignment and Secondary Structure Determination of an Octameric 110 kDa Protein Using TROSY in Triple Resonance Experiments
2000 StandoutNobel
The role of the allosteric B site in the fumarase reaction
2004 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
The Coordination Chemistry of the CF Unit in Fluorocarbons
1997
Was läßt sich aus der molekularen Erkennung in Protein‐Ligand‐Komplexen für das Design neuer Wirkstoffe lernen?
1996
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Works of Xiaochun Ding being referenced
Analogous inhibitors of elastase do not always bind analogously
1994
Structure of the metal-ion-activated diphtheria toxin repressor/ tox operator complex
1998 Nature
NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH
1995
Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH
1995
An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins
1996
Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
1994
Direct Structural Observation of an Acyl-Enzyme Intermediate in the Hydrolysis of an Ester Substrate by Elastase
1994