Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen
2008
Persistent epigenetic differences associated with prenatal exposure to famine in humans
2008 Standout
Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Hypertension
2007
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Mutant G-protein-coupled receptors as a cause of human diseases
2004
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Modulation of vascular development and injury by angiotensin II
1999
ApoE4 Accelerates Early Seeding of Amyloid Pathology
2017
Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
2009 StandoutNobel
Parkinson's disease
2021 Standout
β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation
2002 StandoutNobel
New uses for old drugs
2007 Nature
Localization and Functional Properties of Angiotensin II AT1 Receptors in the Kidney. Focus on Renomedullary Interstitial Cells.
1997
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
1998
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Many little things: one geneticist's view of complex diseases
2005 StandoutNobel
Innovative lead discovery strategies for tropical diseases
2006
Molecular Mechanisms of Human Hypertension
2001 Standout
PLIP: fully automated protein–ligand interaction profiler
2015 Standout
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies
2017
ChEMBL: a large-scale bioactivity database for drug discovery
2011 Standout
Understanding hypertension through genetic manipulation in mice
2000
Genetic deletion and overexpression of angiotensin II receptors
1998
Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight
2018
Old friends in new guise: repositioning of known drugs with structural bioinformatics
2011
Exploring type I angiotensin (AT1) receptor functions through gene targeting
2004
DrugBank: a knowledgebase for drugs, drug actions and drug targets
2007 Standout
Angiotensin induces the urinary peristaltic machinery during the perinatal period.
1998
Role of the Angiotensin Type 2 Receptor Gene in Congenital Anomalies of the Kidney and Urinary Tract, CAKUT, of Mice and Men
1999
Role of the N-terminal Catalytic Domain of Angiotensin-converting Enzyme Investigated by Targeted Inactivation in Mice
2004 StandoutNobel
Characterization and distribution of angiotensin II receptor subtypes in the mouse brain
1998
An early and late peak in microglial activation in Alzheimer’s disease trajectory
2017
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
The Rise and Fall of the Chemoattractant Receptor GPR33
2005 StandoutNobel
Parkinson's disease in the Western Pacific Region
2019
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
2005 StandoutNobel
Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways
2000
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
2009
Divergent functions of angiotensin II receptor isoforms in the brain
2000
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
New insights into the role of TREM2 in Alzheimer’s disease
2018
Renal Vascular Reactivity in Mice
1999
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
Physiology of Local Renin-Angiotensin Systems
2006 Standout
LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease
2019
Importance of quantitative genetic variations in the etiology of hypertension
2000 StandoutNobel
Angiotensin II Type 1–Receptor Activating Antibodies in Renal-Allograft Rejection
2005 Standout
Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 StandoutNobel
Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
2016
Angiotensin II signal transduction pathways
1998
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Transgenic Mice as a Tool to Study the Renin-Angiotensin System
2001
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
2006 Standout
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease
2019
Mammalian G-protein function in vivo: New insights through altered gene expression
2006
Transgenic mice for studies of the renin–angiotensin system in hypertension
2004
Control of Neglected Tropical Diseases
2007 Standout
Drug discovery and development for neglected parasitic diseases
2006
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
2020 Standout
Human genetics, animal models and computer simulations for studying hypertension☆
2004 StandoutNobel
Inflammation in Alzheimer’s disease: Lessons learned from microglia-depletion models
2016
Gene targeting in physiological investigations: studies of the renin-angiotensin system
1998
Hypercholesterolemia Stimulates Angiotensin Peptide Synthesis and Contributes to Atherosclerosis Through the AT 1A Receptor
2004
Protective role of angiotensin II type 2 receptor signaling in a mouse model of pancreatic fibrosis
2008
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)
2020 Standout
Angiotensin II–Induced Vascular Dysfunction Is Mediated by the AT 1A Receptor in Mice
2004
Tau Oligomers and Fibrils Induce Activation of Microglial Cells
2013
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
2001 StandoutNobel
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
β-Arrestins and Cell Signaling
2007 StandoutNobel
Angiotensin AT1BReceptor Mediates Calcium Signaling in Vascular Smooth Muscle Cells of AT1AReceptor–Deficient Mice
1998
New approaches to genetic manipulation of mice: tissue-specific expression of ACE
2003
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Neuroendocrine Effects of Dehydration in Mice Lacking the Angiotensin AT1a Receptor
1999
Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function
2016
A γGT-AT1Areceptor transgene protects renal cortical structure in AT1receptor-deficient mice
2004 StandoutNobel
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Inflammasomes as therapeutic targets for A lzheimer's disease
2016
Gene Targeting Approaches to Analyzing Hypertension
1999 StandoutNobel
The Cinchona Primary Amine-Catalyzed Asymmetric Epoxidation and Hydroperoxidation of α,β-Unsaturated Carbonyl Compounds with Hydrogen Peroxide
2013 StandoutNobel
Mice Lacking Endothelial Angiotensin-Converting Enzyme Have a Normal Blood Pressure
2002 StandoutNobel
Minireview: Overview of the Renin-Angiotensin System—An Endocrine and Paracrine System
2003
Regulation of Sodium Balance and Blood Pressure by the AT1AReceptor for Angiotensin II
2000 StandoutNobel
Synthesis and in vitro DMPK profiling of a 1,2-dioxolane-based library with activity against Plasmodium falciparum
2009
β-Arrestins Regulate Atherosclerosis and Neointimal Hyperplasia by Controlling Smooth Muscle Cell Proliferation and Migration
2008 StandoutNobel
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
2005 StandoutNobel
Reduced growth, abnormal kidney structure, and type 2 (AT 2 ) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT 1A and AT 1B receptors for angiotensin II
1998 StandoutNobel
Physiology of Microglia
2011 Standout
The Cerebellum-Specific Munc13 Isoform Munc13-3 Regulates Cerebellar Synaptic Transmission and Motor Learning in Mice
2001 StandoutNobel
Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol
2009
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Xiaochun Chen being referenced
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
2011
Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes
2015
Prevalence of wearing-off and dyskinesia among the patients with Parkinson’s disease on levodopa therapy: a multi-center registry survey in mainland China
2014
APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice
2015
APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice
2016
A clinical drug library screen identifies astemizole as an antimalarial agent
2006
Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia
2008
Tripchlorolide protects neuronal cells from microglia‐mediated β‐amyloid neurotoxicity through inhibiting NF‐κB and JNK signaling
2009
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
2018
Malaria-Infected Mice Are Cured by a Single Oral Dose of New Dimeric Trioxane Sulfones Which Are Also Selectively and Powerfully Cytotoxic to Cancer Cells
2009
Targeting deletion of angiotensin type 1B receptor gene in the mouse
1997