Citation Impact
Citing Papers
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
2010 StandoutNobel
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
The HIV-1 Nef Protein and Phagocyte NADPH Oxidase Activation
2002
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
2017 StandoutNobel
Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways
2003 StandoutNobel
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
The yeast lysosome-like vacuole: Endpoint and crossroads
2008
Gene Therapy Progress and Prospects: Development of improved lentiviral and retroviral vectors – design, biosafety, and production
2005
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
Structure of PAK1 in an Autoinhibited Conformation Reveals a Multistage Activation Switch
2000
Current status of gene therapy strategies to treat HIV/AIDS
2005
Adoptive T cell therapy for cancer in the clinic
2007
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
2024 StandoutNobel
National Institutes of Health Center for Human Immunology Conference, September 2009
2010
Spinal-cord injury
2002 Standout
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
2002 StandoutNature
Genetic engineering of T cells for immunotherapy
2021
HIV Nef Increases T Cell ERK MAP Kinase Activity
2002
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
2010 Standout
Regulated portals of entry into the cell
2003 StandoutNature
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Gene delivery by lentivirus vectors
2007
Engineering lymphocyte subsets: tools, trials and tribulations
2009
Virus-mediated gene delivery for human gene therapy
2012
RNA interference against viruses: strike and counterstrike
2007
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Formation and Crystallization of Yeast RNA Polymerase II Elongation Complexes
1997 StandoutNobel
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
2011 Standout
Engineered T cells: the promise and challenges of cancer immunotherapy
2016
HIV-1 Nef-Induced Upregulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread
2002
HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots
2002 Standout
Transcriptional elongation by RNA polymerase II is stimulated by transactivators
1994
Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo
2009
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
1997 StandoutNature
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Real-Time Kinetics of Gene Activity in Individual Bacteria
2005 Standout
Manufacturing Validation of Biologically Functional T Cells Targeted to CD19 Antigen for Autologous Adoptive Cell Therapy
2009
Cancer immunotherapy comes of age
2011 StandoutNature
Differential effects of neurotrophins on neuronal survival and axonal regeneration after spinal cord injury in adult rats
2002
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Rho and Rac Take Center Stage
2004 Standout
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
1999
Inhibition of HIV replication: A powerful antiviral strategy by IFN-β gene delivery in CD4+ cells
2007 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
2011
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
2014 Standout
Nef-Induced CD4 Degradation
1999
Macrophages archive HIV‐1 virions for dissemination in trans
2005
Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex
1999 StandoutNobel
CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection
2014
Nef Triggers a Transcriptional Program in T Cells Imitating Single-Signal T Cell Activation and Inducing HIV Virulence Mediators
2001
Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells
2009
Adoptive Immunotherapy for Cancer or Viruses
2014
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix
1997
Promoter-proximal pausing of RNA polymerase II defines a general rate-limiting step after transcription initiation.
1995
Supramolecular Polymerization
2009 Standout
Biology of the p21-Activated Kinases
2003
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia
2011 Standout
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts.
1994
BASIC MECHANISMS OF TRANSCRIPT ELONGATION AND ITS REGULATION
1997
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
2015
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
2008 StandoutNobel
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
2009
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
2002 StandoutNobel
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Cytokine Storm
2020 Standout
The Critical Role of p38 MAP Kinase in T Cell HIV-1 Replication
1997
Cdc42hs Facilitates Cytoskeletal Reorganization and Neurite Outgrowth by Localizing the 58-Kd Insulin Receptor Substrate to Filamentous Actin
2001
Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
2018 Standout
Emerging from the Pak: the p21-activated protein kinase family
1997
Chimeric Antigen Receptor Therapy
2018 Standout
The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments
2000 StandoutNobel
Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody
2010
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
1995
Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells
2012
Effects of the simian virus 40 origin of replication on transcription from the human immunodeficiency virus type 1 promoter
1995
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Viral Subversion of the Immune System
2000
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
The Engagement of Activating FcγRs Inhibits Primate Lentivirus Replication in Human Macrophages
2006 StandoutNobel
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
2001
Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles
2001
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Endogenously Expressed nef Uncouples Cytokine and Chemokine Production from Membrane Phenotypic Maturation in Dendritic Cells
2002 StandoutNobel
Distinct activated and non-activated RNA polymerase II complexes in yeast.
1996
Works of Xiaobin Lü being referenced
FDA Approval Summary: Tisagenlecleucel for Treatment of Patients with Relapsed or Refractory B-cell Precursor Acute Lymphoblastic Leukemia
2018
Interactions between HIV1 Nef and Vacuolar ATPase Facilitate the Internalization of CD4
1998
CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1
1996
Safe two‐plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one‐step protocol
2004
Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load
2004
Regulatory Considerations for Novel Gene Therapy Products: A Review of the Process Leading to the First Clinical Lentiviral Vector
2005
Neurotrophins BDNF and NT‐3 promote axonal re‐entry into the distal host spinal cord through Schwann cell‐seeded mini‐channels
2001
The human immunodeficiency virus type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by Tat
1993
Antisense-Mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-Based Vector Results in Severely Attenuated Mutants Incapable of Developing Resistance
2004
Gene transfer in humans using a conditionally replicating lentiviral vector
2006
p21-Activated Kinase 1 Plays a Critical Role in Cellular Activation by Nef
2000
Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels
2001