Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Requirements for DNA hairpin formation by RAG1/2
2007
The DDE Motif in RAG-1 Is Contributed in trans to a Single Active Site That Catalyzes the Nicking and Transesterification Steps of V(D)J Recombination
2001
CRISPR/Cas9 in Genome Editing and Beyond
2016
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Determinants of HMGB Proteins Required To Promote RAG1/2-Recombination Signal Sequence Complex Assembly and Catalysis during V(D)J Recombination
2005
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Both High Mobility Group (HMG)-boxes and the Acidic Tail of HMGB1 Regulate Recombination-activating Gene (RAG)-mediated Recombination Signal Synapsis and Cleavage in Vitro
2005
Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis
2009 StandoutNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference
2015
A view on drug resistance in cancer
2019 StandoutNature
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
The bounty of RAGs: recombination signal complexes and reaction outcomes
2004
RAG1-DNA Binding in V(D)J Recombination
2003
Epigenetic regulation of aging stem cells
2011
Multivariate analysis of clinicopathological and prognostic significance of miRNA 106b~25 cluster in gastric cancer
2019
Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment
2015
The DSIF Subunits Spt4 and Spt5 Have Distinct Roles at Various Phases of Immunoglobulin Class Switch Recombination
2012 StandoutNobel
The genetics of ageing
2010 StandoutNature
Harnessing the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated Cas9 system to disrupt the hepatitis B virus
2015
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
The Mediator complex: a central integrator of transcription
2015
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Genome scale screening identification of SaCas9/gRNAs for targeting HIV-1 provirus and suppression of HIV-1 infection
2018
Genome-Wide Occupancy Profile of Mediator and the Srb8-11 Module Reveals Interactions with Coding Regions
2006
Analyzing real-time PCR data by the comparative CT method
2008 Standout
A decade of discovery: CRISPR functions and applications
2017
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Therapeutic genome editing: prospects and challenges
2015
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease
2014
A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
2016
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Ordered assembly of the V(D)J synaptic complex ensures accurate recombination
2002
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells
2015
Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication
2015
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Transcription — guarding the genome by sensing DNA damage
2004
Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase
2006
Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression
2009
The Hallmarks of Aging
2013 Standout
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Chapter 2 DNA-PK
2008
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
2015
STAGA Recruits Mediator to the MYC Oncoprotein To Stimulate Transcription and Cell Proliferation
2007
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
2016 Science
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1
2004
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9
2015
Mutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase
2002
The Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire
2000
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development
2008
CRISPR-Cas: biology, mechanisms and relevance
2016 StandoutNobel
Genomic Engineering and the Future of Medicine
2015 StandoutNobel
A RAG-1/RAG-2 Tetramer Supports 12/23-Regulated Synapsis, Cleavage, and Transposition of V(D)J Recombination Signals
2002
Genetics of Longevity in Model Organisms: Debates and Paradigm Shifts
2012
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Disease Tolerance as a Defense Strategy
2012 StandoutScience
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Functional Organization of Single and Paired V(D)J Cleavage Complexes
2001
Cancer Genome Landscapes
2013 StandoutScience
Prospective Estimation of Recombination Signal Efficiency and Identification of Functional Cryptic Signals in the Genome by Statistical Modeling
2003
Alternative RNA Splicing Produces Multiple Forms of c-Myb with Unique Transcriptional Activities
2008
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Mitochondrial HEP27 Is a c-Myb Target Gene That Inhibits Mdm2 and Stabilizes p53
2010
Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study
2009
Fine Structure and Activity of Discrete RAG-HMG Complexes on V(D)J Recombination Signals
2002
The RAG Proteins and V(D)J Recombination: Complexes, Ends, and Transposition
2000
Assembly of the RAG1/RAG2 Synaptic Complex
2002
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Xianming Mo being referenced
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
2014
Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain
2005
In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
2017
RAG1 and RAG2 Cooperate in Specific Binding to the Recombination Signal Sequence in Vitro
1999
Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins
2003
A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1
2000
Correlation between serum CA724 and gastric cancer: multiple analyses based on Chinese population
2012
Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations
2009
A tumor hypoxic niche protects human colon cancer stem cells from chemotherapy
2012
Ras Induces Mediator Complex Exchange on C/EBPβ
2004
A C-Terminal Region of RAG1 Contacts the Coding DNA during V(D)J Recombination
2001
Subnuclear Localization of Ku Protein: Functional Association with RNA Polymerase II Elongation Sites
2002
A RAG1 and RAG2 Tetramer Complex Is Active in Cleavage in V(D)J Recombination
1999