Xavier Bernard

ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

Head and neck squamous cell carcinoma

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

R-Loops as Cellular Regulators and Genomic Threats

PROTAC targeted protein degraders: the past is prologue

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

ROS and the DNA damage response in cancer

Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

Alkylating Agent–Induced NRF2 Blocks Endoplasmic Reticulum Stress–Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis

Proteasomal Degradation of p53 by Human Papillomavirus E6 Oncoprotein Relies on the Structural Integrity of p53 Core Domain

EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

E6 Proteins from Diverse Papillomaviruses Self-Associate Both In Vitro and In Vivo