Standout Papers
Citation Impact
Citing Papers
The Spatial Organization of the Human Genome
2013
Mouse B-Type Lamins Are Required for Proper Organogenesis But Not by Embryonic Stem Cells
2011 Science
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
2009 StandoutScience
CRISPR/Cas9 in Genome Editing and Beyond
2016
Nuclear lamins are not required for lamina‐associated domain organization in mouse embryonic stem cells
2015
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
The UK Biobank resource with deep phenotyping and genomic data
2018 StandoutNature
Chromatin architecture reorganization during stem cell differentiation
2015 Nature
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
The impact of rare and low-frequency genetic variants in common disease
2017
Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
2016
Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9
2017
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
An Expanded View of Complex Traits: From Polygenic to Omnigenic
2017 Standout
Benefits and limitations of genome-wide association studies
2019
The role of nuclear lamin B1 in cell proliferation and senescence
2011
Nuclear landscape of HIV-1 infection and integration
2016
Genetic effects on gene expression across human tissues
2017 StandoutNature
Intermediate filaments: primary determinants of cell architecture and plasticity
2009
N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
2016
DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina
2012
The nucleoskeleton as a genome-associated dynamic 'network of networks'
2011
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
2011
Three-dimensional genome architecture: players and mechanisms
2015
Multi-omics approaches to disease
2017
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
2011
Facile and General Synthesis of Photoactivatable Xanthene Dyes
2011 StandoutNobel
The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm
2011
Chromatin plasticity and genome organization in pluripotent embryonic stem cells
2010
Chromatin-Driven Behavior of Topologically Associating Domains
2014
The Human Transcription Factors
2018 Standout
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
H3K9 methyltransferase G9a and the related molecule GLP
2011
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING)
2017
Integrative annotation of chromatin elements from ENCODE data
2012
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape
2013
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Atlas of Subcellular RNA Localization Revealed by APEX-Seq
2019
The potential of 3D‐FISH and super‐resolution structured illumination microscopy for studies of 3D nuclear architecture
2012
Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution
2009
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Genome organization in and around the nucleolus
2011
The Hierarchy of the 3D Genome
2013
Cell-Type-Specific Profiling of Gene Expression and Chromatin Binding without Cell Isolation: Assaying RNA Pol II Occupancy in Neural Stem Cells
2013
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Probabilistic modeling of Hi-C contact maps eliminates systematic biases to characterize global chromosomal architecture
2011
Charting histone modifications and the functional organization of mammalian genomes
2010
Chromatin dynamics during cellular reprogramming
2013 Nature
10 Years of GWAS Discovery: Biology, Function, and Translation
2017 Standout
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
2016 Standout
Higher-order chromatin structure: bridging physics and biology
2012
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
The role of senescent cells in ageing
2014 StandoutNature
The Hallmarks of Aging
2013 Standout
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription
2008
Field-resolved infrared spectroscopy of biological systems
2020 StandoutNatureNobel
Topological domains in mammalian genomes identified by analysis of chromatin interactions
2012 StandoutNature
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Comprehensive Integration of Single-Cell Data
2019 Standout
ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing
2016 StandoutNobel
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate
2012
Spatial partitioning of the regulatory landscape of the X-inactivation centre
2012 StandoutNature
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
CTCF: Master Weaver of the Genome
2009 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Genome Architecture: Domain Organization of Interphase Chromosomes
2013
Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome
2012
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
2013 Nature
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
2010
CTCF, cohesin, and histone variants: connecting the genome
2011
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Cell Biology of theCaenorhabditis elegansNucleus
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
FIREWORKS: a bottom-up approach to integrative coessentiality network analysis
2020
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence
2013
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
2014 StandoutNobel
Discovery and Annotation of Functional Chromatin Signatures in the Human Genome
2009
Works of Wouter Meuleman being referenced
Mapping of lamin A- and progerin-interacting genome regions
2012
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes
2021
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
2008 StandoutNature
Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence
2012
Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation
2010
The Insulator Protein SU(HW) Fine-Tunes Nuclear Lamina Interactions of the Drosophila Genome
2010
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
2015