Citation Impact
Citing Papers
Systematic discovery of nonobvious human disease models through orthologous phenotypes
2010
An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
2014 Science
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
2009 Standout
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/β-catenin signaling
2011
Linking class-switch recombination with somatic hypermutation
2001 StandoutNobel
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal–mesenchymal interaction
2011
The complex world of WNT receptor signalling
2012
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
Focal adhesion kinase: in command and control of cell motility
2005 Standout
Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer
2012
CD300 molecule regulation of human dendritic cell functions
2012
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
2011 Standout
LGR6 Is a High Affinity Receptor of R-Spondins and Potentially Functions as a Tumor Suppressor
2012
Secreted and Transmembrane Wnt Inhibitors and Activators
2012
Regeneration of the endothelium as a novel therapeutic strategy for acute lung injury
2006
Forkhead Transcription Factors: Key Players in Development and Metabolism
2002
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Antibody Class Switching
1996
The cellular geography of Aurora kinases
2003
Assigning Function to Yeast Proteins by Integration of Technologies
2003 StandoutNobel
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
2004
Nucleases of the Metallo-β-lactamase Family and Their Role in DNA and RNA Metabolism
2007
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes
2016 StandoutNobel
Angiogenesis in health and disease
2003 Standout
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells
2005 StandoutNobel
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
2012 Nature
Structures of the Cancer-Related Aurora-A, FAK, and EphA2 Protein Kinases from Nanovolume Crystallography
2002
Functional Analysis of Sox10 Mutations Found in Human Waardenburg-Hirschsprung Patients
1998
Developmental regulation of the growth plate
2003 StandoutNature
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
DMY is a Y-specific DM-domain gene required for male development in the medaka fish
2002 StandoutNature
FoxM1 is required for execution of the mitotic programme and chromosome stability
2005 Standout
The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation
2015
Cloning and functional analysis of the Sry -related HMG box gene, Sox18
2001
Wnt/β-Catenin Signaling and Disease
2012 Standout
Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6
2011
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
2002 Standout
The Transcription Factors L-Sox5 and Sox6 Are Essential for Cartilage Formation
2001
Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies
2010
The emerging roles of forkhead box (Fox) proteins in cancer
2007
Wnt11 Promotes Osteoblast Maturation and Mineralization through R-spondin 2
2009
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
2011 Nature
R‐spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway
2010
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Activation‐Induced Cytidine Deaminase Links Class Switch Recombination and Somatic Hypermutation
2003 StandoutNobel
Ubiquitous Expression of the Forkhead Box M1B Transgene Accelerates Proliferation of Distinct Pulmonary Cell Types following Lung Injury
2003
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
2020 Standout
Wnt Antagonists Bind through a Short Peptide to the First β-Propeller Domain of LRP5/6
2011
Phylogeny of the SOX Family of Developmental Transcription Factors Based on Sequence and Structural Indicators
2000
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Expression of EphrinB2 Identifies a Stable Genetic Difference Between Arterial and Venous Vascular Smooth Muscle as Well as Endothelial Cells, and Marks Subsets of Microvessels at Sites of Adult Neovascularization
2001
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
AID mutant analyses indicate requirement for class-switch-specific cofactors
2003 StandoutNobel
SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter
2001
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
2012 Standout
Endothelial cell–restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury
2006
Spatial and temporal dynamics of the endothelium
2005
The Forkhead Box M1 Transcription Factor Is Essential for Embryonic Development of Pulmonary Vasculature
2005
Constitutive Phosphorylation Mutation in Fas-associated Death Domain (FADD) Results in Early Cell Cycle Defects
2007
From head to toes: the multiple facets of Sox proteins
1999 Standout
The prognostic landscape of genes and infiltrating immune cells across human cancers
2015 Standout
P2Y2 Nucleotide Receptors Enhance α-Secretase-dependent Amyloid Precursor Protein Processing
2005
Aurora-kinase inhibitors as anticancer agents
2004
Update on Wnt signaling in bone cell biology and bone disease
2011
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Modeling Development and Disease with Organoids
2016 Standout
A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease
2003
The spindle-assembly checkpoint in space and time
2007 Standout
LGR4 and LGR5 are R‐spondin receptors mediating Wnt/β‐catenin and Wnt/PCP signalling
2011
The role of Dickkopf-1 in bone development, homeostasis, and disease
2008
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Acute Myeloid Leukemia
2015 Standout
Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation
2002 StandoutNobel
Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals
1997
Premature Expression of the Winged Helix Transcription Factor HFH-11B in Regenerating Mouse Liver Accelerates Hepatocyte Entry into S Phase
1999
COPII-mediated vesicle formation at a glance
2010 StandoutNobel
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver
2001
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Antibody therapy for acute myeloid leukaemia
2013
New and unexpected: forkhead meets ARF
2004
COVID-19 and its implications for thrombosis and anticoagulation
2020 Standout
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells
2012
Essential Dosage-Dependent Functions of the Transcription Factor Yin Yang 1 in Late Embryonic Development and Cell Cycle Progression
2006
Covid-19 in Critically Ill Patients in the Seattle Region — Case Series
2020 Standout
Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase
2005
Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
2001 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
2002
Derivation of a robust mouse mammary organoid system for studying tissue dynamics
2016
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
2006 Standout
Works of Wouter Korver being referenced
The First Propeller Domain of LRP6 Regulates Sensitivity to DKK1
2009
Regulation of proteolytic processing of the amyloid β-protein precursor of Alzheimer’s disease in transfected cell lines and in brain slices
1994
In vivo and in vitro IgE isotype switching in human B lymphocytes: Evidence for a predominantly direct IgM to IgE class switch program
1994
High expression of the HMG box factor Sox-13 in arterial walls during embryonic development
1998
Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor Trident
1998
The Winged-Helix Transcription Factor Trident is Expressed in Actively Dividing Lymphocytes
1997
The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the γ‐tubulin complex
2003
TheSox-13Gene: Structure, Promoter Characterization, and Chromosomal Localization
1999
Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia
2009
The winged-helix transcription factor Trident is expressed in cycling cells
1997
Monoclonal antibodies against IREM-1: potential for targeted therapy of AML
2009
The HumanTRIDENT/HFH-11/FKHL16Gene: Structure, Localization, and Promoter Characterization
1997
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
2000
R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism
2008