Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
In Vitro Selection of Highly Modified Cyclic Peptides That Act as Tight Binding Inhibitors
2012 Nobel
Pancreatic Phospholipase A 2 : Isolation of the Human Gene and cDNAs from Porcine Pancreas and Human Lung
1986
HIV Envelope Suppresses CD4+ T Cell Activation Independent of T Regulatory Cells
2008 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation
2005
Peptide inhibitor of pancreatic lipase selected by phage display using different elution strategies
2005
The MyD88-Dependent, but Not the MyD88-Independent, Pathway of TLR4 Signaling Is Important in Clearing Nontypeable Haemophilus influenzae from the Mouse Lung
2005 StandoutNobel
Characterizing sequence variation in the VP1 capsid proteins of foot and mouth disease virus (serotype 0) with respect to virion structure
1998
START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins
1999
Structural characterization of human monoclonal cold agglutinins: Evidence for a distinct primary sequence‐defined VH4 idiotype
1990
Synthesis of Foot-and-mouth Disease Virus Capsid Proteins in Insect Cells Using Baculovirus Expression vectors
1990
Biology of Secretory Phospholipase A2
2008
Amino acid changes outside the G-H loop of capsid protein VP1 of type O foot-and-mouth disease virus confer resistance to neutralization by antipeptide G-H serum
1993
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Inference of Macromolecular Assemblies from Crystalline State
2007 Standout
The effect of peptides containing the arginine-glycine-aspartic acid sequence on the adsorption of foot-and-mouth disease virus to tissue culture cells
1990
Peptide Ligands Stabilized by Small Molecules
2014
The role of Asp‐49 and other conserved amino acids in phospholipases A2 and their importance for enzymatic activity
1989
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Mouse protection test as a predictor of the protective capacity of synthetic foot-and-mouth disease vaccines
1991
Guillain-Barré syndrome
2016 Standout
Encoded libraries of chemically modified peptides
2015 StandoutNobel
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1998 StandoutNature
Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67
1995
Survey of the year 2004 commercial optical biosensor literature
2005
Structure and receptor binding
2003
Guillain–Barré Syndrome
2012 Standout
Antibody recognition of picornaviruses and escape from neutralization: a structural view
1995
Identification of a fifth neutralizable site on type O foot-and-mouth disease virus following characterization of single and quintuple monoclonal antibody escape mutants
1993
Extensive antigenic diversification of foot-and-mouth disease virus by amino acid substitutions outside the major antigenic site
1992
Translocation of phospholipase A2 from cytosol to membranes in rat brain induced by calcium ions
1990
Phage-encoded combinatorial chemical libraries based on bicyclic peptides
2009 StandoutNobel
Structurally Diverse Cyclisation Linkers Impose Different Backbone Conformations in Bicyclic Peptides
2012
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host
1995
Conformational Restriction of Peptides Using Dithiol Bis-Alkylation
2016
Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa
2018
Phospholipase A2 Biochemistry
2008
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Evolution of foot-and-mouth disease virus
2003
Identification of new tag sequences with differential and selective recognition properties for the anti-FLAG monoclonal antibodies M1, M2 and M5
1997
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices
1994
Sequence analysis of monoclonal antibody resistant mutants of type O foot and mouth disease virus: Evidence for the involvement of the three surface exposed capsid proteins in four antigenic sites
1990
Neutralization antigenic sites on type Asia-1 foot-and-mouth disease virus defined by monoclonal antibody-resistant variants
1997
Anti-ganglioside antibody-mediated neuronal cytotoxicity and its protection by intravenous immunoglobulin: implications for immune neuropathies
2004
Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.
1992 StandoutNobel
Assembly of foot-and-mouth disease virus empty capsids synthesized by a vaccinia virus expression system
1995
Developments in foot-and-mouth disease vaccines
1991
Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity
1996
Peptide therapeutics: current status and future directions
2014 Standout
Origin and physiological roles of inflammation
2008 StandoutNature
Molecular determinants of the pathogenesis of disease due to non-typableHaemophilus influenzae
1999
Survey of the year 2003 commercial optical biosensor literature
2004
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020 StandoutNature
Exploring sequence space: harnessing chemical and biological diversity towards new peptide leads
2017
The structure and antigenicity of a type C foot-and-mouth disease virus
1994
The expanding superfamily of phospholipase A2 enzymes: classification and characterization
2000 Standout
Structural Elements of Secretory Phospholipases A2 Involved in the Binding to M-type Receptors
1995
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
Potential for biomolecular imaging with femtosecond X-ray pulses
2000 StandoutNature
Structure-based design of peptide presentation on a viral surface: the crystal structure of a plant/animal virus chimera at 2.8 å resolution
1996
Bactericidal properties of murine intestinal phospholipase A2.
1995
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Acetone‐Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling
2015
Synthetic peptide vaccines: success at last
1995
Structure of human chorionic gonadotropin at 2.6 å resolution from MAD analysis of the selenomethionyl protein
1994
Parvovirus B19
2004 Standout
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Strain-specific Immune Response to Haemophilus influenzae in Chronic Obstructive Pulmonary Disease
2003
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Evidence for Positive Selection in Foot-and-Mouth Disease Virus Capsid Genes From Field Isolates
2001
Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites
1994
Detection of Antibodies in Blood Plasma Using Bioluminescent Sensor Proteins and a Smartphone
2016
Ribosomal Synthesis of N-Methyl Peptides
2008 StandoutNobel
In Vitro Selection of Functional Lantipeptides
2012 Nobel
Bacterial Infection in Chronic Obstructive Pulmonary Disease in 2000: a State-of-the-Art Review
2001
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
2012
Bicyclic Peptide Inhibitor Reveals Large Contact Interface with a Protease Target
2012 StandoutNobel
Ribosomal Synthesis of Peptidase-Resistant Peptides Closed by a Nonreducible Inter-Side-Chain Bond
2008
Phage display libraries of differently sized bicyclic peptides
2012
Postbinding events mediated by human immunodeficiency virus type 1 are sensitive to modifications in the D4-transmembrane linker region of CD4
1996
Foot-and-Mouth Disease
2004 Standout
Vaccines prepared from chimeras of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies and protective immunity to multiple serotypes of FMDV
1994
Structure and function of phospholiphase A2
1981
Evidence of recombination in the capsid-coding region of type A foot-and-mouth disease virus
2002
Fluorogenic Imines for Fluorescent Detection of Mannich-Type Reactions of Phenols in Water
2008
Molecular and Biological Characterization of Human Monoclonal Antibodies Binding to the Spike and Nucleocapsid Proteins of Severe Acute Respiratory Syndrome Coronavirus
2005
Human Parvovirus B19
2002 Standout
Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor
2005 StandoutScience
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Structure of porcine pancreatic phospholipase A2 at 2·6resolution and comparison with bovine phospholipase A2
1983 StandoutNobel
Amino-terminal processing of mutant forms of yeast iso-1-cytochrome c. The specificities of methionine aminopeptidase and acetyltransferase.
1985
Notes: Point Mutations in the Yeast Histone H4 Gene Prevent Silencing of the Silent Mating Type Locus HML
1990 StandoutNobel
Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4
1995
Interfacial Catalysis: the Mechanism of Phospholipase A 2
1990 StandoutScience
Circular dichroism of porcine, bovine, and equine pancreatic phospholipases A2 and their zymogens Unusual conformations simulating helix content
1977
Stapled Peptide Inhibitors of Autophagy Adapter LC3B
2020
Analysis of Loops that Mediate Protein–Protein Interactions and Translation into Submicromolar Inhibitors
2016
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Expression of porcine pancreatic phospholipase A2. Generation of active enzyme by sequence-specific cleavage of a hybrid protein fromEscherichia coli
1987
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Chimeric polioviruses that include sequences derived from two independent antigenic sites of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies against FMDV in guinea pigs
1991
Active site and catalytic mechanism of phospholipase A2
1981 Nature
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
RNA Display Methods for the Discovery of Bioactive Macrocycles
2018
Cloning and expression of a membrane receptor for secretory phospholipases A2.
1994
In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue
1986 StandoutScience
Ca2+ion binding to porcine pancreatic phospholipase A2 and its function in enzyme-lipid interaction
1978
Modification of Carboxylate Groups in Bovine Pancreatic Phospholipase A2
1981
The Primary Structure of Bovine Pancreatic Phospholipase A2
1978
Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy
2017
Bicyclization and Tethering to Albumin Yields Long-Acting Peptide Antagonists
2012
Interfacial Enzymology: The Secreted Phospholipase A2-Paradigm
2001
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Rapid biocompatible macrocyclization of peptides with decafluoro-diphenylsulfone
2016
Two subunits of the canine signal peptidase complex are homologous to yeast SEC11 protein.
1990 StandoutNobel
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Three-dimensional structure and disulfide bond connections in bovine pancreatic phospholipase A2
1978
Prepro-alpha-factor has a cleavable signal sequence.
1988 StandoutNobel
Conversion of pig pancreas phospholipase A2 by protein engineering into enzyme active against Escherichia coli treated with the bactericidal/permeability-increasing protein
1991
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
RGD sequence of foot-and-mouth disease virus isessential for infecting cells via the natural receptor but can be bypassed by anantibody-dependent enhancement pathway.
1994
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
2004 StandoutScience
Antigenic stability of foot-and-mouth disease virus variants on serial passage in cell culture
1991
Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction
2012
Works of Wouter C. Puijk being referenced
Mimotopes: realization of an unlikely concept
2000
Manipulation of antipeptide immune response by varying the coupling of the peptide with the carrier protein
1989
Rapid and Quantitative Cyclization of Multiple Peptide Loops onto Synthetic Scaffolds for Structural Mimicry of Protein Surfaces
2005
Mapping of a discontinuous and highly conformational binding site on follicle stimulating hormone subunit-β (FSH-β) using domain Scan™ and Matrix Scan™ technology
2004
Effects of Monoclonal Antibodies to Specific Epitopes of Rat Interleukin‐1 Beta (IL‐Iβ) on IL‐1β‐Induced ACTH, Corticosterone and IL‐6 Responses in Rats
1995
Structural aspects of antibody-antigen interaction revealed through small random peptide libraries
1996
Identification of epitopes within beta lactoglobulin recognised by polyclonal antibodies using phage display and PEPSCAN
1998
Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS™ technology
2007
Identification of linear epitopes on Semliki Forest virus E2 membrane protein and their effectiveness as a synthetic peptide vaccine
1991
Comparative studies of tyrosine modification in pancreatic phospholipases. 2. Properties of the nitrotyrosyl, aminotyrosyl, and dansylaminotyrosyl derivatives of pig, horse, and ox phospholipases A2 and their zymogens
1979
First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs
1994
Effects of substitution of the absolutely invariant Gln-4 and Phe-5 in bovine pancreatic phospholipase A2 on enzymic activity and substrate binding properties
1982
Modification of Arginine Residues in Porcine Pancreatic Phospholipase A2
1981
High enzymatic activity of specifically iodinated bovine phospholipase A2
1978
The Primary Structure of the Phosphatidylcholine‐Exchange Protein from Bovine Liver
1980
Location of CD4 dimerization site explains critical role of CDR3-like region in HIV-1 infection and T-cell activation and implies a model for complex of coreceptor-MHC
1993
Antigenic sites on foot-and-mouth disease virus type A10
1988
The amino acid sequence of the phospholipase A2 isoenzyme from porcine pancreas
1979
Functional Reconstruction of Structurally Complex Epitopes using CLIPS™ Technology
2009
Fine mapping of outer membrane protein P2 antigenic sites which vary during persistent infection by Haemophilus influenzae
1996
Semisynthesis of phospholipase A2. Preparation and properties of arginine-6 bovine pancreatic phospholipase A2
1981
Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity
2016
Localization of an immunodominant domain on baculovirus-produced parvovirus B19 capsids: correlation to a major surface region on the native virus particle
1992
The primary structure of phospholipase A2 from porcine pancreas A reinvestigation
1977
Semisynthesis of Phospholipase A2
1983
Synthetic peptides based upon a three-dimensional model for the receptor recognition site of follicle-stimulating hormone exhibit antagonistic or agonistic activity at low concentrations.
1992