Citation Impact
Citing Papers
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
Immunoblotting analysis of protein‐protein crosslinks within the 50S ribosomal subunit of Escherichia coli
1989
Automated electron microscope tomography using robust prediction of specimen movements
2005 Standout
Acromegaly
2006 Standout
An improved strategy for automated electron microscopic tomography
2004
mTOR Signaling in Growth Control and Disease
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Electron tomography of molecules and cells
1999
Correction of autofocusing errors due to specimen tilt for automated electron tomography
2003
Electron Tomography of Ice-Embedded Prokaryotic Cells
1998
Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy
2011
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Ovarian cancer
2014 Standout
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
2001 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
Molecular defects in the pathogenesis of pituitary tumours
2003
Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
2019 StandoutNobel
Automated most-probable loss tomography of thick selectively stained biological specimens with quantitative measurement of resolution improvement
2004
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Pattern Recognition Receptors and Inflammation
2010 Standout
Loading of Vesicles into Soft Amphiphilic Nanotubes using Osmosis
2015 StandoutNobel
Advances in the treatment of advanced oestrogen-receptor-positive breast cancer
2016
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
2000 StandoutNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Perspectives of Molecular and Cellular Electron Tomography
1997
Protein functions in pre-mRNA splicing
1997
Formation of the 3′ end of histone mRNA: Getting closer to the end
2007
Crystal Structures of Two Sm Protein Complexes and Their Implications for the Assembly of the Spliceosomal snRNPs
1999
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy
2003 StandoutNobel
Autonomous motors of a metal–organic framework powered by reorganization of self-assembled peptides at interfaces
2012 StandoutNobel
Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit
1999 StandoutNatureNobel
Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex
1999 StandoutNobel
Immunoelectron microscopic localization of ribosomal proteins BS8, BS9, BS20, BL3 and BL21 on the surface of 30S and 50S subunits from Bacillus stearothermophilus
1993
PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types
2013
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
2017
Automated high‐throughput electron tomography by pre‐calibration of image shifts
2002
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells
2011
CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors
2014
Low-Dose Automated Electron Tomography: A Recent Implementation
1997 StandoutNobel
Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials
2021
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Implications of a poroelastic cytoplasm for the dynamics of animal cell shape
2008
The PI3K Pathway in Human Disease
2017 Standout
Comparative cross-linking study on the 50S ribosomal subunit from Escherichia coli
1989
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae
2000 StandoutNature
A phase 1 study of the sachet formulation of the oral dual PI3K/mTOR inhibitor BEZ235 given twice daily (BID) in patients with advanced solid tumors
2015
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
A visual approach to proteomics
2006
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
2013
Emerging targeted agents in metastatic breast cancer
2013
The role and regulation of blebs in cell migration
2013
The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein
2004
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method
2002
The association of the U1-specific 70K and C proteins with U1 snRNPs is mediated in part by common U snRNP proteins.
1994
The Initial Stages of Template-Controlled CaCO 3 Formation Revealed by Cryo-TEM
2009 StandoutScience
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
2008 StandoutNobel
Labeling the peptidyltransferase center of the Escherichia coli ribosome with photoreactive tRNA(Phe) derivatives containing azidoadenosine at the 3' end of the acceptor arm: a model of the tRNA-ribosome complex.
1989
Microenvironment and Radiation Therapy
2012
A model for the spatial arrangement of the proteins in the large subunit of the Escherichia coli ribosome.
1988
Coupled Growth and Division of Model Protocell Membranes
2009 StandoutNobel
Cloning, sequencing, and overexpression of genes for ribosomal proteins from Bacillus stearothermophilus.
1991 StandoutNobel
Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors
2011
Robust excitons inhabit soft supramolecular nanotubes
2014 StandoutNobel
Activity of Transmembrane Proteins Induces Magnification of Shape Fluctuations of Lipid Membranes
1999
Configurations of fluid membranes and vesicles
1997
Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
2005
Properties of giant vesicles
2000
A Novel Genetic Screen for snRNP Assembly Factors in Yeast Identifies a Conserved Protein, Sad1p, Also Required for Pre-mRNA Splicing
1999
A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma
2016
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs.
1995
A Phase II Study of BEZ235 in Patients with Everolimus-resistant, Advanced Pancreatic Neuroendocrine Tumours.
2016
Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy
2016
Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
1993 StandoutNobel
Part 14: Pediatric Advanced Life Support
2010 Standout
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation
2004 StandoutNobel
Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
1994 StandoutNobel
Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance
1998 StandoutNobel
Protrusive growth from giant liposomes driven by actin polymerization
1999
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Works of Wolfgang Hackl being referenced
Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
2011
NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity
2012
Serum HER‐2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy
2005
CDKN2A/p16 inactivation is related to pituitary adenoma type and size
2001
Phase 1/1b dose escalation and expansion study of BEZ235, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumors including patients with advanced breast cancer
2018
Phase I safety, pharmacokinetic, and pharmacodynamic study of the oral phosphatidylinositol-3-kinase and mTOR inhibitor BGT226 in patients with advanced solid tumors
2012
Shape instability of a biomembrane driven by a local softening of the underlying actin cortex
2000
Three‐dimensional location of ribosomal protein BL2 from Bacillus stearothermophilus, a key component of the peptidyl transferase center
1988
Serum epidermal growth factor receptor/HER‐2 predicts poor survival in patients with metastatic breast cancer
2006
Energy filtered electron tomography of ice-embedded actin and vesicles
1997
Direct binding of small nuclear ribonucleoprotein G to the Sm site of small nuclear RNA
1992
Molecular Cloning and Subcellular Localisation of the snRNP-associated Protein 69KD, a Structural Homologue of the Proto-oncoproteins TLS and EWS, with RNA and DNA-binding Properties
1996
Immunoelectron microscopic localisation of ribosomal proteins from Bacillus stearothermophilus that are homologous to Escherichia coli L1, L6, L23 and L29
1988
Prevalence of cervical spine injuries in patients with facial trauma
2001
Assemble, nuclear import and function of U7 snRNPs studied by microinjection of synthetic U7 RNA intoXenopusoocytes
1995
Multi-Level Targeting of the Phosphatidylinositol-3-Kinase Pathway in Non-Small Cell Lung Cancer Cells
2012
Shape Changes of Self-Assembled Actin Bilayer Composite Membranes
1998
Effects of Fully and Partially Solubilized Amphiphiles on Bilayer Bending Stiffness and Temperature Dependence of the Effective Tension of Giant Vesicles
1997
A 69-kD protein that associates reversibly with the Sm core domain of several spliceosomal snRNP species
1994
A phase I/IB dose-escalation study of BEZ235 in combination with trastuzumab in patients with PI3-kinase or PTEN altered HER2+ metastatic breast cancer.
2012
First-in-human phase I study of the oral PI3K inhibitor BEZ235 in patients (pts) with advanced solid tumors.
2010