Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Autonomic Nerve Development Contributes to Prostate Cancer Progression
2013 StandoutScience
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
2003 Standout
Role of Calcitonin Gene-Related Peptide in Light-Aversive Behavior: Implications for Migraine
2009
Orexin-induced food intake involves neuropeptide Y pathway
2000
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
2006 StandoutNobel
Delayed Upregulation of ATP P2X3 Receptors of Trigeminal Sensory Neurons by Calcitonin Gene-Related Peptide
2006
Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism
2010
The Nonpeptide Calcitonin Gene-Related Peptide Receptor Antagonist BIBN4096BS Lowers the Activity of Neurons with Meningeal Input in the Rat Spinal Trigeminal Nucleus
2005
Inhibitory effect of BIBN4096BS on cephalic vasodilatation induced by CGRP or transcranial electrical stimulation in the rat
2004
Management of acute organophosphorus pesticide poisoning
2007 Standout
Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor
1998
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Central nervous system control of food intake and body weight
2006 StandoutNature
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Blockade and reversal of spinal morphine tolerance by peptide and non‐peptide calcitonin gene‐related peptide receptor antagonists
2000
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function
2004
Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery
2002 Standout
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Regulation of Neuropeptide Y Release by Neuropeptide Y Receptor Ligands and Calcium Channel Antagonists in Hypothalamic Slices
1999
A receptor subtype involved in neuropeptide-Y-induced food intake
1996 Nature
Modulation of nocioceptive transmission with calcitonin gene-related peptide receptor antagonists in the thalamus
2010
The NPY system in stress, anxiety and depression
2004
A Pair-Feeding Study Reveals That a Y5 Antagonist Causes Weight Loss in Diet-Induced Obese Mice by Modulating Food Intake and Energy Expenditure
2006
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine
2004 Standout
Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment
2002
G Protein-coupled Receptors
1998 StandoutNobel
Peptidomimetic design
1998
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
CH/π Attraction: The Origin of Enantioselectivity in Transfer Hydrogenation of Aromatic Carbonyl Compounds Catalyzed by Chiralη6-Arene-Ruthenium(II) Complexes
2001 StandoutNobel
Calcitonin gene‐related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat
2004
Migraine — Current Understanding and Treatment
2002 Standout
A role for ghrelin in the central regulation of feeding
2001 StandoutNature
Role of hypothalamic neuropeptide Y in feeding and obesity
1999
The receptor activity modifying protein family of G protein coupled receptor accessory proteins
2004
GPCR modulation by RAMPs
2005
NPY receptors as potential targets for anti‐obesity drug development
2011
Cholinergic innervation and function in the prostate gland
2002
The pharmacology of CGRP-responsive receptors in cultured and transfected cells
2004
Obesity and the Regulation of Energy Balance
2001 Standout
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage
2009 Standout
Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones
1991
Diencephalic and brainstem mechanisms in migraine
2011
Receptor Activity-modifying Proteins 2 and 3 Have Distinct Physiological Functions from Embryogenesis to Old Age
2007 StandoutNobel
Site-directed mutagenesis of the putative human muscarinic M2 receptor binding site
1999
The molecular pharmacology of CGRP and related peptide receptor subtypes
2000
Adrenomedullin signaling is necessary for murine lymphatic vascular development
2007
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
2004
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Immunohistochemical Localization of Calcitonin Receptor–Like Receptor and Receptor Activity–Modifying Proteins in the Human Cerebral Vasculature
2002
Structural Changes Accompanying Intramolecular Electron Transfer: Focus on Twisted Intramolecular Charge-Transfer States and Structures
2003 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS, the First Selective Small Molecule Calcitonin Gene-Related Peptide Receptor Antagonist, Following Single Intravenous Administration in Healthy Volunteers
2004
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Reinterpretation of the anomalous fluorescense of -n,n-dimethylamino-benzonitrile
1973
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
Ground- and excited-state dipole moments of some nitroaromatics: Evidence for extensive charge transfer in twisted nitrobenzene systems
1990
Regioselective Synthesis of 3-Benzazepinones and Unexpected 5-Bromo-3-benzazepinones
2010
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
2006 StandoutNobel
Absorption and electroabsorption on amorphous films of polyvinylcarbazole and trinitrofluorenone
1973
interaction in the conformation of organic compounds. A database study
1999
Regioselective synthesis of the 1-bromo-4-phenyl-tetrahydro-7-amino-benzocyclohepten-6-one, a subnanomolar aminopeptidase-N/CD13 inhibitor
2012
Synthesis of 3,4-dihydroisoquinolines, 2-alkyl(Acyl)-1(2H)-3,4-dihydroisoquinolinones, 2-alkyl-1(2H)-isoquinolinones and 1-alkyl-2(2H)-quinolinones by oxidation with potassium permanganate
1996
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothelial cells and induce its desensitisation by different mechanisms
2006
Electric field-dependent nonphotorefractive gratings in a nonlinear photoconducting polymer
1994 StandoutNobel
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Involvement of Neuropeptide Y Y1 Receptors in the Regulation of Neuroendocrine Corticotropin-Releasing Hormone Neuronal Activity
2007
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
The CGRP-Antagonist, BIBN4096BS Does not Affect Cerebral or Systemic Haemodynamics in Healthy Volunteers
2005
Artificial Molecular Machines
2000 StandoutNobel
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
2000
A Field Guide to Foldamers
2001 Standout
Octreotide is not Effective in the Acute Treatment of Migraine
2004
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Intramolecular Radiative and Radiationless Charge Recombination Processes in Donor−Acceptor Carbazole Derivatives
1997
Structural characterization and binding sites of G-protein-coupled receptors
1996
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Vascular Actions of Calcitonin Gene-Related Peptide and Adrenomedullin
2004
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
Muscarinic Receptor Agonists and Antagonists
2001
Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions
2011 Standout
Quantum Mechanical Continuum Solvation Models
2005 Standout
Syntheses of piperidine and perhydroazepine derivatives, precursors of two selective antagonists of muscarinic M2 receptors: AF-DX 384 and its perhydroazepine isomer
1996
Quenching Processes in Hydrogen-Bonded Pairs: Interactions of Excited Fluorenone with Alcohols and Phenols
1997
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
Enhanced Vascular Responses to Adrenomedullin in Mice Overexpressing Receptor-Activity–Modifying Protein 2
2005
Deviations from Kleinman symmetry of the second-order polarizability tensor in molecules with low-lying perpendicular electronic bands
1993
Receptor Activity-Modifying Proteins: RAMPing up Adrenomedullin Signaling
2006
Proton-Coupled Electron Transfer
2012 Standout
Calcitonin Gene-Related Peptide: Physiology and Pathophysiology
2014
Cgrp May Play A Causative Role in Migraine
2002 Standout
Peptide Receptors as Molecular Targets for Cancer Diagnosis and Therapy
2003
Works of Wolfgang Eberlein being referenced
Neuropeptide Y and the nonpeptide antagonist BIBP 3226 share an overlapping binding site at the human Y1 receptor.
1996
BIIE0246: A selective and high affinity neuropeptide Y Y2 receptor antagonist
1999
Specific bradycardic agents. 1. Chemistry, pharmacology, and structure-activity relationships of substituted benzazepinones, a new class of compounds exerting antiischemic properties
1990
The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226
1994
Tricyclic compounds as selective muscarinic receptor antagonists. 3. Structure-selectivity relationships in a series of cardioselective (M2) antimuscarinics
1989
BIBP 3226, the first selective neuropeptide Y1 receptor antagonist: A review of its pharmacological properties
1996
Characterisation of calcitonin gene-related peptide receptors in rat atrium and vas deferens: evidence for a [Cys(Et)2,7]hCGRP-preferring receptor
2000
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
2000
Labeling of neuropeptide Y receptors in SK-N-MC cells using the novel, nonpeptide Y1 receptor-selective antagonist [3H]BIBP3226
1995
Subtype selectivity of the novel nonpeptide neuropeptide Y Y1 receptor antagonist BIBO 3304 and its effect on feeding in rodents
1998
Tricyclic compounds as selective antimuscarinics. 2. Structure-activity relationships of M1-selective antimuscarinics related to pirenzepine
1988
Therapeutic potential of CNS-active M2 antagonists: Novel structures and pharmacology
1993
Die Beeinflussung der optischen Absorption von Molekülen durch ein äußeres elektrisches Feld. V. Übergangsmomentrichtungen und Dipolmomente der niedrigen Elektronenzustände in 4‐Nitranilin, 1‐Nitro‐3,5‐diaminobenzol, 3,5‐Dinitroanilin, Carbazol und 3,6‐Dinitrocarbazol
1967
Über das Elektronenspektrum von Fluorenon Beobachtung einer durch ein elektrisches Feld induzierten Absorptionsbande
1968
Development of Human Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonists. 1. Potent and Selective Small Molecule CGRP Antagonists. 1-[N2-[3,5-Dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1- piperidinyl]carbonyl]-d -tyrosyl]-l -lysyl]-4-(4-pyridinyl)piperazine: The First CGRP Antagonist for Clinical Trials in Acute Migraine
2005
Subtype selectivity and antagonistic profile of the nonpeptide Y1 receptor antagonist BIBP 3226.
1995
Tricyclic compounds as selective antimuscarinics. 1. Structural requirements for selectivity towards the muscarinic acetylcholine receptor in a series of pirenzepine and imipramine analogs
1987
[Anti-ulcer agent pirenzepine (LS 519)--a tricyclic compound with particular physico-chemical properties (author's transl)].
1977